Results 261 to 270 of about 160,266 (354)

The Role of Metacaspases and Other Proteins Involved in the Apoptosis of <i>Leishmania:</i> Review Article. [PDF]

Iran J Parasitol
Aghaei M, Aghaei S, Shahmoradi Z, Hejazi SH.   +3 more
europepmc   +1 more source

Identification of caspases that cleave presenilin‐1 and presenilin‐2 [PDF]

, 1999
Marc Van de Craen, Chris De Jonghe, Ilse Van den Brande, Wim Declercq, Geert Van Gassen, Wim Van Criekinge, Inge Vanderhoeven, Walter Fiers, Christine Van Broeckhoven, Lydia Hendriks, Peter Vandenabeele   +10 more
openalex   +1 more source

EccDNA‐Driven VPS41 Amplification Alleviates Genotoxic Stress via Lysosomal KAI1 Degradation

Advanced Science, EarlyView.
Following ionizing radiation, eccDNA‐mediated VPS41 amplification slightly increases its expression but fails to prevent apoptosis. Introducing exogenous eccDNA or VPS41 enhances VPS41‐KAI1 interaction, promoting lysosomal degradation of KAI1. This process inhibits apoptotic signaling, enhancing cell survival and resistance to radiation‐induced damage.
Bin Shi, Ping Yang, Huaijin Qiao, Jinchen He, Bin Song, Hao Bai, Fengdi Jiang, Yining Zhang, Qian Li, Tao Yan, Wenlin Tu, Daojiang Yu, Shuyu Zhang   +12 more
wiley   +1 more source

Caspase-8: Arbitrating Life and Death in the Innate Immune System. [PDF]

Cells
Gupta S, Lopez MA, Ektesabi AM, Tsoporis JN, Vaswani CM, Gandhi SY, Fairn GD, Dos Santos CC, Marshall JC.   +8 more
europepmc   +1 more source

Caspases are the main executioners of Fas-mediated apoptosis, irrespective of the ceramide signalling pathway [PDF]

, 1998
Susana Gamen, Alberto Díaz Añel, Andrés Piňeiro, Javier Naval   +3 more
openalex   +1 more source

Targeted Penetrating Motif Engineering of BH3 Mimetic: Harnessing Non‐Canonical Amino Acids for Coinhibition of MCL‐1 and BCL‐xL in Acute Myeloid Leukemia

Advanced Science, EarlyView.
A structure‐guided peptide derived from a non‐canonical amino acid library simultaneously targets MCL‐1 and BCL‐xL to overcome apoptotic resistance in acute myeloid leukemia. Fused with a CXCR4‐binding motif, the engineered peptide exhibits selective intracellular delivery and potent in vivo efficacy, offering a promising therapeutic strategy against ...
Zhe Wang, Ruizhi Lai, Xinpei Wang, Xu Chen, Youjian Zhou, Shengbin Li, Xiaohui Qiu, Zekai Zeng, Jianye Yuan, Jinghuan Mao, Zhidong Chen, Junqing Wang   +11 more
wiley   +1 more source

Immunohistochemical Analysis of Interleukin-1β–Converting Enzyme/Ced-3 Family Protease, CPP32/Yama/Caspase-3, in Hodgkin's Disease [PDF]

, 1997
Mukesh Chhanabhai, Stanisław Krajewski, Maryla Krajewska, Hong‐Gang Wang, John C. Reed, Randy D. Gascoyne   +5 more
openalex   +1 more source

Consequences of in vitro exposure of chicken spermatozoa to the fungicide tebuconazole. [PDF]

Poult Sci
Napierkowska S, Froment P, Dupont J, Płuciennik N, Babapour A, Krywko-Valencia S, Niżański W, Kowalczyk A, Partyka A.   +8 more
europepmc   +1 more source

Bax-α promotes apoptosis induced by cancer chemotherapy and accelerates the activation of caspase 3-like cysteine proteases in p53 double mutant B lymphoma Namalwa cells [PDF]

, 1998
Estelle Schmitt, Alain Steyaert, Guido Cimoli, Richard Bertrand   +3 more
openalex   +1 more source

Caspase-8, association with Alzheimer\u27s disease and functional analysis of rare variants [PDF]

, 2017
Cruchaga, Carlos, et al.,, Lord, Jenny
core   +1 more source