Results 91 to 100 of about 29,420 (294)

ESCMID‐EFISG Survey on Diagnostic and Therapeutic Capacity for Invasive Fungal Infections in Belgium, the Netherlands, and Luxembourg: A Focus on High Azole Resistance

Mycoses, Volume 68, Issue 7, July 2025.
ABSTRACT Introduction Invasive fungal infections (IFI) are a major clinical challenge, particularly in immunocompromised patients, and are associated with high morbidity and mortality. With the increasing prevalence of immunosuppressive conditions and ageing populations, the incidence of IFI is rising globally.
Robina Aerts, Lize Cuypers, Eelco F. J. Meijer, Michel Kohnen, Jacques F. Meis, Oliver A. Cornely, Katrien Lagrou, Jon Salmanton‐García, Alex Wagemakers, Stefan Vestjens, Peter Verbeeck, Geert Vanheule, Marc Vandevelde, Jens van Van Praet, Bruno van Van Herendael, Jaap van Doesum, Karin van Van Dijk, Alieke van der Van der Hoeven, Wendy W. J. van de Van de Sande, Marijke Reynders, Ann Packeu, Yarah Overmeire, Claudy Oliveira‐dos‐Santos, Eric Nulens, Alexandre Mzabi, Astrid Muyldermans, Isabel Montesinos, Willem Melchers, Johan Maertens, Karel Maelegheer, Sybren Lekkerkerk, Nathalie Layios, Eva Kolwijck, Stijn Jonckheere, Louis Ide, Marie‐Pierre Hayette, Ferry Hagen, Pieter‐Jan Haas, Truus Goegebuer, Peggy Godschalk, Anne‐Isabelle de Moreau, Emmanuel de Laere, Julien de Greef, Deborah de Geyter, Peter Croughs, Philippe Clevenbergh, Jolien Claessens, Ga‐Lai Chong, Reinoud Cartuyvels, Jochem Buil, Roger Bruggemann, Jerina Boelens, An Boel, Robbert Bentvelsen   +53 more
wiley   +1 more source

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 22: Suitability of taxonomic units notified to EFSA until March 2025

EFSA Journal, Volume 23, Issue 7, July 2025.
Abstract The qualified presumption of safety (QPS) process was developed to assess the safety of microorganisms used in food and feed chains. During the period covered by this Statement, no new information warranted changes to the status of previously recommended QPS taxonomic units.
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Marianne Chemaly, Ingvar Sundh, Fulvio Barizzone, Justine Dastouet, Nadya Doyle, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

Caspofungin for the treatment of candidaemia in patients with haematological malignancies [PDF]

Clinical Microbiology and Infection, 2008
Abstract Objective: To evaluate the efficacy of Caspofungin in patients with hematological malignancies (HM) and candidemia Design: The study was prospectively conducted in 11 Hematology Divisions in a tertiary care or university hospital setting.; neutropenic hematological patients with clinical evidence of infection and ...
Pagano, Livio, Fianchi, Luana, Fanci, R, Candoni, A, Caira, Morena, Posteraro, Brunella, Morselli, M, Valentini, Cg, Farina, Giuliana, Mitra, Me, Offidani, M, Sanguinetti, Maurizio, Tosti, Me, Nosari, A, Leone, Giuseppe, Viale, P.   +15 more
openaire   +6 more sources

Caspofungin Weight-Based Dosing Supported by a Population Pharmacokinetic Model in Critically Ill Patients

Antimicrobial Agents and Chemotherapy, 2020
The objective of this study was to develop a population pharmacokinetic model and to determine a dosing regimen for caspofungin in critically ill patients. Nine blood samples were drawn per dosing occasion.
A. Märtson, K. V. D. van der Elst, Anette Veringa, J. Zijlstra, A. Beishuizen, T. S. van der Werf, J. Kosterink, M. Neely, J. Alffenaar   +8 more
semanticscholar   +1 more source

Aneuploidy enables cross-tolerance to unrelated antifungal drugs in Candida parapsilosis

Frontiers in Microbiology, 2023
Candida parapsilosis is an emerging major human fungal pathogen. Echinocandins are first-line antifungal drugs for the treatment of invasive Candida infections.
Liu-liu Sun, Liu-liu Sun, Hao Li, Hao Li, Tian-hua Yan, Yong-bing Cao, Yuan-ying Jiang, Feng Yang   +7 more
doaj   +1 more source

Biosynthesis of the Fungal Cyclic Lipodepsipeptide Pleosporacin, a New Selective Inhibitor of the Phytopathogen Botrytis cinerea

ChemBioChem, Volume 26, Issue 12, June 16, 2025.
Bioactivity‐guided isolation led to the discovery of a potent and selective inhibitor of the phytopathogen Botrytis cinerea, pleosporacin (1), from mycelia extracts of the fungal strain Pleosporales sp. IBWF 020‐21. The biosynthesis of the nonribosomal cyclic lipodepsipeptide 1 was elucidated via heterologous reconstitution in Aspergillus oryzae ...
Carsten Wieder, Rainer Wiechert, Alexander Yemelin, Louis Pergaud Sandjo, Eckhard Thines, Till Opatz, Anja Schüffler   +6 more
wiley   +1 more source

Calcinosis cutis in epidermal necrolysis: role of caspofungin?

Journal of the European Academy of Dermatology and Venereology, 2021
No abstract ...
Hester Colboc, Hester Colboc, Vincent Frochot, Vincent Frochot, Dominique Bazin, Marine Badrignans, N. de Prost, Philippe Moguelet, Saskia Ingen-Housz-Oro, Nicolas Ortonne, Emmanuel Letavernier, Emmanuel Letavernier, A. Boury, Ellie Tang, T. Bettuzzi   +14 more
openaire   +4 more sources

Antifungal Caspofungin Sensitizes MRSA Isolates Towards Zabofloxacin, A Proteomic Study

Journal of Pure and Applied Microbiology, 2020
The incidence of methicillin-resistant Staphylococcus aureus (MRSA) having an increased rate of fluoroquinolone resistance is currently noted in Egypt necessitating the implication of new strategies to restrain the rapid spread of this resistance.
Nelly M. Mohamed, Azza S. Zakaria, Eva A. Edward   +2 more
doaj   +1 more source

Pitfalls associated with the use of molecular diagnostic panels in the diagnosis of cryptococcal meningitis [PDF]

, 2017
We report the case of a kidney transplantation patient on chronic immunosuppressive therapy presenting with subacute meningitis. The final diagnosis of cryptococcal meningitis was delayed due to 2 false-negative cryptococcal results on a molecular ...
Burnham, Carey-Ann, Dubberke, Erik, Franklin, Alexander, Lainhart, William, O\u27Halloran, Jane A, Powderly, William   +5 more
core   +2 more sources

Bioinspirierte Kationische Antimikrobielle Polymere

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
Dieser Übersichtsartikel behandelt Membran‐aktive kationische Polymere mit antimikrobiellen Eigenschaften. Im Fokus stehen Aspekte wie die Polymerarchitektur, Stimuli‐responsive antimikrobielle Polymere sowie Synergien von Polymeren und anderen Verbindungen.
Heliya Javadi, Anne‐Catherine Lehnen, Matthias Hartlieb   +2 more
wiley   +1 more source