Results 31 to 40 of about 25,252 (242)

Synergistic Interaction of Caspofungin Combined with Posaconazole against FKS Wild-Type and Mutant Candida auris Planktonic Cells and Biofilms

Antibiotics, 2022
Candida auris is a potential multidrug-resistant pathogen able to cause biofilm-associated outbreaks, where frequently indwelling devices are the source of infections.
Noémi Balla, Fruzsina Kovács, Bence Balázs, Andrew M. Borman, Aliz Bozó, Ágnes Jakab, Zoltán Tóth, Ola Kobaissi, László Majoros, Renátó Kovács   +9 more
doaj   +1 more source

Candida albicans Strains Adapted to Caspofungin Due to Aneuploidy Become Highly Tolerant under Continued Drug Pressure

Microorganisms, 2022
Candida albicans is a prevalent fungal pathogen of humans. Understanding the development of decreased susceptibility to ECN drugs of this microbe is of substantial interest, as it is viewed as an intermediate step allowing the formation of FKS1 ...
Farha Husain, Anshuman Yadav, Sudisht K. Sah, Jeffrey J. Hayes, Elena Rustchenko   +4 more
doaj   +1 more source

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]

, 2017
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N, Istel, F, Jenull, S, Lion, T, Nogueira, MF, Walker, L A   +5 more
core   +1 more source

Absent in vitro interaction between chloroquine and antifungals against Aspergillus fumigatus [PDF]

, 2017
This work was supported by Medical Mycology Section, Department of Medical Microbiology, Radboud University Medical Centre, Nijmegen, the Netherlands.
Seyedmousavi, Seyedmojtaba, van der Lee, Henrich, Verweij, Paul, Warris, Adilia   +3 more
core   +1 more source

A Linear 19-Mer Plant Defensin-Derived Peptide Acts Synergistically with Caspofungin against Candida albicans Biofilms

Frontiers in Microbiology, 2017
Public health problems are associated with device-associated biofilm infections, with Candida albicans being the major fungal pathogen. We previously identified potent antibiofilm combination treatment in which the antifungal plant defensin HsAFP1 is co ...
Tanne L. Cools, Caroline Struyfs, Caroline Struyfs, Jan W. Drijfhout, Soňa Kucharíková, Soňa Kucharíková, Celia Lobo Romero, Celia Lobo Romero, Patrick Van Dijck, Patrick Van Dijck, Marcelo H. S. Ramada, Marcelo H. S. Ramada, Carlos Bloch, Bruno P. A. Cammue, Bruno P. A. Cammue, Karin Thevissen   +15 more
doaj   +1 more source

Antifungal Susceptibility Profile of Aspergillus Strains Isolated From the Lower Respiratory Tract in Eastern Indian Patients: A Hospital-Based Study. [PDF]

Microbiologyopen
Treatment for chronic to invasive pulmonary aspergillosis typically involves azole antifungal drugs, although studies have shown varying minimum inhibitory concentrations (MIC) for these medications, with a growing concern over voriconazole resistance.
Nikhil A, Choudhury S, Bhatia M, Tiwari AK, Srivastava R, Prasad A, Tilak R, Gupta MK, Narayan RJ.   +8 more
europepmc   +2 more sources

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew, Johnson, Elizabeth M., Kean, Ryan, Ramage, Gordon, Rautemaa-Richardson, Riina, Richardson, Malcolm D., Sherry, Leighann   +6 more
core   +4 more sources

Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]

, 2016
Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core   +3 more sources

Susceptibility to caspofungin is regulated by temperature and is dependent on calcineurin in Candida albicans

Microbiology Spectrum, 2023
Candida albicans is a prevalent opportunistic human fungal pathogen. Echinocandins are first-line drugs for the treatment of invasive candidiasis. Molecular mechanisms of resistance to echinocandins have been extensively studied; however, the effect of ...
Lijun Zheng, Yi Xu, Chen Wang, Feng Yang, Yubo Dong, Liangsheng Guo   +5 more
doaj   +1 more source

Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Pharmacology, 2020
Caspofungin is the first echinocandin antifungal agent that licented for pediatric use in invasive candidiasis and aspergillosis. In this study, we evaluated the population pharmacokinetics of caspofungin and investigate appropriate dosing optimization ...
Chang-He Niu, Hua Xu, Liu-Liu Gao, Ying-Ming Nie, Li-Peng Xing, Li-Peng Yu, San-Lan Wu, Yang Wang   +7 more
doaj   +1 more source