Results 41 to 50 of about 29,725 (304)

Treatment of Primary Pulmonary Aspergillosis: An Assessment of the Evidence. [PDF]

, 2016
Aspergillus spp. are a group of filamentous molds that were first described due to a perceived similarity to an aspergillum, or liturgical device used to sprinkle holy water, when viewed under a microscope.
Stewart, Ethan R, Thompson, George R
core   +3 more sources

Biofilm-forming capability of highly virulent, multidrug-resistant Candida auris [PDF]

, 2017
The emerging multidrug-resistant yeast pathogen Candida auris has attracted considerable attention as a source of healthcare–associated infections. We report that this highly virulent yeast has the capacity to form antifungal resistant biofilms sensitive
Borman, Andrew, Johnson, Elizabeth M., Kean, Ryan, Ramage, Gordon, Rautemaa-Richardson, Riina, Richardson, Malcolm D., Sherry, Leighann   +6 more
core   +3 more sources

Caspofungin in the Treatment of Symptomatic Candiduria [PDF]

Clinical Infectious Diseases, 2007
Because the urine concentrations achieved by echinocandin antifungal agents are low, drugs from this class are excluded from consideration when candiduria treatment is selected.We performed a retrospective view (sponsored by Merck Research Laboratories) of case records of patients participating in phase II-III clinical studies of caspofungin to ...
Jack D. Sobel, C. Joy Lipka, Susan K. Bradshaw, Nicholas A. Kartsonis   +3 more
openaire   +3 more sources

Population Pharmacokinetics of Caspofungin and Dosing Optimization in Children With Allogeneic Hematopoietic Stem Cell Transplantation

Frontiers in Pharmacology, 2020
Caspofungin is the first echinocandin antifungal agent that licented for pediatric use in invasive candidiasis and aspergillosis. In this study, we evaluated the population pharmacokinetics of caspofungin and investigate appropriate dosing optimization ...
Chang-He Niu, Hua Xu, Liu-Liu Gao, Ying-Ming Nie, Li-Peng Xing, Li-Peng Yu, San-Lan Wu, Yang Wang   +7 more
doaj   +1 more source

Susceptibility to caspofungin is regulated by temperature and is dependent on calcineurin in Candida albicans

Microbiology Spectrum, 2023
Candida albicans is a prevalent opportunistic human fungal pathogen. Echinocandins are first-line drugs for the treatment of invasive candidiasis. Molecular mechanisms of resistance to echinocandins have been extensively studied; however, the effect of ...
Lijun Zheng, Yi Xu, Chen Wang, Feng Yang, Yubo Dong, Liangsheng Guo   +5 more
doaj   +1 more source

Medication Complications in Extracorporeal Membrane Oxygenation. [PDF]

, 2017
The need for extracorporeal membrane oxygenation (ECMO) therapy is a marker of disease severity for which multiple medications are required. The therapy causes physiologic changes that impact drug pharmacokinetics.
Aebi, Ami G. Shah, Anderson, Arlt, Barr, Barthelemy, Beiderlinden, Bein, Bembea, Bhatt-Meht, Boucher, Brandi N. Thoma, Brown, Buck, Buscher, Chung, Dagan, Dagan, de Montmollin, De Rosa, DeGrado, Donadello, Donadello, Dzierba, Erstad, Esper, Eyler, Flordelis Lasierra, Glauber, Greenberg, Gélisse, Hadidi, Hertzog, Hraiech, Hynynen, Johnston, Kawada, Kim, Koster, Krueger, Lamarche, Latronico, Lemaitre, Levison, Malfertheiner, Mehta, Michelle Peahota, Moore, Mousavi, Mulla, Mulla, Muntean, Oliver, Paden, Park, Perkins, Peters, Pettignano, Phillips, Pieri, Potter, Preston, Protti, Ranucci, Riker, Roberts, Roos, Rosen, Ruiz, Rybak, Saini, Sanfilippo, Satyapriya, Schmith, Shekar, Shekar, Shekar, Shekar, Shekar, Sherwin, Sklar, Smith, Spriet, Staudacher, Strunk, Subramaniam, Szefner, Tellor, Trudzinski, Tulman, Turner, Veinstein, Vilay, Wagner, Walter K. Kraft, Welsch, Wen, Wildschut, Wu, Young   +99 more
core   +2 more sources

Management of a case of Candida albicans endogenous endophthalmitis with intravitreal caspofungin

Indian Journal of Ophthalmology, 2017
We report a case of Candida albicans endogenous endophthalmitis treated with intravitreal caspofungin. The patient was a known case of acute lymphoblastic leukemia on chemotherapy and presented to us with features suggestive of endogenous endophthalmitis.
Harshali Manish Yadav, Boben Thomas, Cherian Thampy, Tandava Krishnan Panaknti   +3 more
doaj   +1 more source

Caspofungin Induced Cell Wall Changes of Candida Species Influences Macrophage Interactions

Frontiers in Cellular and Infection Microbiology, 2020
Candida species are known to differ in their ability to cause infection and have been shown to display varied susceptibilities to antifungal drugs. Treatment with the echinocandin, caspofungin, leads to compensatory alterations in the fungal cell wall ...
L. Walker, C. Munro
semanticscholar   +1 more source

CASPOFUNGIN FOR CANDIDA ENDOCARDITIS

The Pediatric Infectious Disease Journal, 2004
Wojciech Mrówczyński, Michał Wojtalik
openalex   +3 more sources

Pharmacokinetics and Safety of Intravitreal Caspofungin [PDF]

Antimicrobial Agents and Chemotherapy, 2014
ABSTRACT Caspofungin exhibits potent antifungal activities against Candida and Aspergillus species. The elimination rate and retinal toxicity of caspofungin were determined in this study to assess its pharmacokinetics and safety in the treatment of fungal endophthalmitis ...
Ying-Cheng Shen, Chun-Yuan Wang, Chiao-Ying Liang, Li-Chen Wei, Min-Yen Hsu, Hon-Leung Yuen, Keng-Hung Lin   +6 more
openaire   +3 more sources