Results 61 to 70 of about 25,252 (242)
Treatment of Aspergillosis. [PDF]
, 2018 Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core +1 more source
Optimizing Prolonged (6 h) Normothermic Machine Perfusion of Donor Kidneys (PROPER Study)
Artificial Organs, EarlyView.Prolonged ex situ normothermic machine perfusion of donor kidneys up to 6 h is feasible, maintaining viability and histological integrity. Key protocol optimizations include fresh red blood cells, albumin supplementation, and urine recirculation—laying the groundwork for assessment and potential pretransplant interventions in future clinical trials ...
Asel S. Arykbaeva +14 more
wiley +1 more source
Oma1 Links Mitochondrial Protein Quality Control and TOR Signaling To Modulate Physiological Plasticity and Cellular Stress Responses [PDF]
, 2016 ACKNOWLEDGMENTS We thank Dennis Winge (University of Utah) and the members of the Khalimonchuk laboratory for critical comments. We also thank Christoph Schuller (University of Natural Resources, Austria) and Paul Herman (Ohio State University) for ...
Barrientos, Antoni +10 more
core +2 more sources
Journal of Microscopy, EarlyView.Abstract Hyphal forms of human pathogenic fungi cause invasive disease in humans, but the hyphal response to antifungals is understudied. In the major fungal pathogens Aspergillus fumigatus and Candida albicans, we used microfluidic‐coupled, fluorescence‐mediated live‐cell imaging to capture the real‐time responses of fungal hyphae to clinical ...
D. D. Thomson +3 more
wiley +1 more source
Utilization and comparative effectiveness of caspofungin and voriconazole early after market approval in the U.S. [PDF]
PLoS ONE, 2014 Both caspofungin and voriconazole were initially approved by the FDA with very narrow indications. Our aim was to evaluate the utilization patterns and comparative effectiveness of these agents early after marketing before any labeling change occurred ...
Sibel Ascioglu, K Arnold Chan
doaj +1 more source
Frontiers in Pharmacology, 2022 Background: To develop a population pharmacokinetic (PPK) model for caspofungin, identify parameters influencing caspofungin pharmacokinetics, and assess the required probability of target attainment (PTA) and cumulative fraction of response (CFR) for ...
Qianting Yang +13 more
doaj +1 more source
The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi [PDF]
, 2016 Acknowledgements TG and CF are funded by FEDER funds through the Operational Programme Competitiveness Factors – COMPETE and national funds by FCT – Foundation for Science and Technology under the strategic project UID/NEU/04539/2013. C.F. is a recipient
Fernandes, Chantal +2 more
core +1 more source
Clinical Case Reports, Volume 14, Issue 2, February 2026.ABSTRACT With the improvement of survival in multiple myeloma (MM), therapy‐related acute myeloid leukemia (t‐AML) has emerged as a clinically relevant second primary malignancy (SPM). We report a case of MM evolving into t‐AML after multi‐agent chemotherapy and review the literature on therapy‐related leukemias in MM.
Songdi Chen +10 more
wiley +1 more source
BMC Infectious Diseases, 2010 Background A prospective observational registry assessed real world experience with caspofungin monotherapy or combination therapy for the initial or salvage treatment of proven or probable invasive aspergillosis (IA).
Chandwani Sheenu +7 more
doaj +1 more source
MicrobiologyOpen, Volume 15, Issue 1, February 2026.Essential oils with anti‐HSV‐1 activity were identified through literature review and tested against Candida to develop a formulation for co‐infections. The blend was assessed for anti‐inflammatory properties, allergenic potential via standardized BAT, and overall antiviral efficacy.
Maura Di Vito +11 more
wiley +1 more source