Results 81 to 90 of about 29,725 (304)
Efficacy and safety of caspofungin in obese patients [PDF]
Medical Mycology, 2011 Safety and efficacy outcomes were retrospectively compared for obese versus non-obese patients who received standard caspofungin doses for different clinical conditions in nine clinical trials within the Merck caspofungin database. Favorable outcomes were as defined in specific protocols.
Desmond M. Ryan +2 more
openaire +3 more sources
British Journal of Haematology, EarlyView.Summary Understanding bloodstream infection (BSI) epidemiology is crucial for optimizing antibiotic therapy in paediatric haematology–oncology patients undergoing chemotherapy or haematopoietic cell transplantation (HCT). However, updated paediatric data remain scarce.
Francesco Baccelli +35 more
wiley +1 more source
Utilization and comparative effectiveness of caspofungin and voriconazole early after market approval in the U.S. [PDF]
PLoS ONE, 2014 Both caspofungin and voriconazole were initially approved by the FDA with very narrow indications. Our aim was to evaluate the utilization patterns and comparative effectiveness of these agents early after marketing before any labeling change occurred ...
Sibel Ascioglu, K Arnold Chan
doaj +1 more source
Journal of the American Medical Association (JAMA), 2019 Importance Children, adolescents, and young adults with acute myeloid leukemia are at high risk of life-threatening invasive fungal disease with both yeasts and molds.
B. Fisher +13 more
semanticscholar +1 more source
The importance of subclasses of chitin synthase enzymes with myosin-like domains for the fitness of fungi [PDF]
, 2016 Acknowledgements TG and CF are funded by FEDER funds through the Operational Programme Competitiveness Factors – COMPETE and national funds by FCT – Foundation for Science and Technology under the strategic project UID/NEU/04539/2013. C.F. is a recipient
Fernandes, Chantal +2 more
core +1 more source
A Review on Aspergillosis in Turkey: As a Main Fungal Disease in Poultry
Veterinary Medicine and Science, Volume 11, Issue 6, November 2025.ABSTRACT Background Aspergillosis, a fungal disease caused by various species of the genus Aspergillus, poses a significant threat to the health and productivity of turkeys. Objective The current review aims to synthesize current knowledge regarding the aetiology, pathogenesis, clinical manifestations, diagnostic methods and management strategies ...
Ansam Naji Aboud Alhassani +9 more
wiley +1 more source
Antimicrobial Agents and Chemotherapy, 2020 The objective of this study was to develop a population pharmacokinetic model and to determine a dosing regimen for caspofungin in critically ill patients. Nine blood samples were drawn per dosing occasion.
A. Märtson +8 more
semanticscholar +1 more source
Treatment of Aspergillosis. [PDF]
, 2018 Infections caused by Aspergillus spp. remain associated with high morbidity and mortality. While mold-active antifungal prophylaxis has led to a decrease of occurrence of invasive aspergillosis (IA) in those patients most at risk for infection ...
Hoenigl, Martin, Jenks, Jeffrey D
core +1 more source
Evaluation of aminocandin and caspofungin against Candida glabrata including isolates with reduced caspofungin susceptibility [PDF]
Journal of Antimicrobial Chemotherapy, 2008 Aminocandin is an investigational echinocandin with excellent activity against Candida species, including Candida albicans and Candida tropicalis. However, few data are available for this agent versus Candida glabrata. We compared the in vitro potency and in vivo efficacy of aminocandin and caspofungin against clinical isolates of C. glabrata including
Nathan P. Wiederhold +7 more
openaire +3 more sources
Repositioning Antimicrobial Peptides Against WHO‐Priority Fungi
Advanced Science, Volume 12, Issue 37, October 6, 2025.The growing burden of drug‐resistant fungal infections, driven by pathogens such as Candida auris, Cryptococcus neoformans, and Aspergillus fumigatus, underscores the urgent need for novel antifungal therapies. This review explores antimicrobial peptides as promising agents with membrane‐disruptive activity, immunomodulatory properties, and delivery ...
Cesar Augusto Roque‐Borda +12 more
wiley +1 more source