Results 31 to 40 of about 229,451 (392)
Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer.
New England Journal of Medicine, 2019 BACKGROUND Apalutamide is an inhibitor of the ligand-binding domain of the androgen receptor. Whether the addition of apalutamide to androgen-deprivation therapy (ADT) would prolong radiographic progression-free survival and overall survival as compared ...
K. Chi +19 more
semanticscholar +1 more source
Animals, 2019 This study assessed the efficacy of pre-operative injected lignocaine and peri-operative topical vapocoolant spray, administered as most practical for incorporation into routine calf castration procedures.
Dominique Van der Saag +4 more
doaj +1 more source
Effect of Castration on Some Physiological Aspect in Rats: Effect of Testosterone Hormone [PDF]
مجلة التربية والعلم, 2010 This study provides novel information on the role of castration and testosterone hormone replacement at (5ng/kg B. Wt.) in rats in the parameters each of red blood corpuscles count, hemoglobin concentration, packed cell volume (PCV), erythrocytes indexes,
A. A. Hassan
doaj +1 more source
Persistent neutrophil to lymphocyte ratio >3 during treatment with enzalutamide and clinical outcome in patients with castration-resistant prostate cancer [PDF]
, 2016 The baseline value of neutrophil to lymphocyte ratio (NLR) has been found to be prognostic in patients with metastatic castration resistant prostate cancer (CRPC). We evaluated the impact of baseline NLR and its change in patients receiving enzalutamide.
Caffo, Orazio +15 more
core +3 more sources
Animal, 2016 Methods to reduce castration-related pain in piglets are still issues of concern and interest for authorities and producers. Our objectives were to estimate the effectiveness of two protocols of local anesthesia (lidocaine and the combination of ...
C. Bonastre +6 more
doaj +1 more source
Prevalence and risk factors for urinary incontinence in bitches five years after ovariohysterectomy [PDF]
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021 Ovariohysterectomy (OHE) is the most performed elective surgery in veterinary medicine. Although this procedure brings benefits both to the animal and public health, acquired urinary incontinence is a possible complication resultant from it.
B. Leupolt +3 more
doaj +2 more sources
Niclosamide enhances abiraterone treatment via inhibition of androgen receptor variants in castration resistant prostate cancer. [PDF]
, 2016 Considerable evidence from both clinical and experimental studies suggests that androgen receptor variants, particularly androgen receptor variant 7 (AR-V7), are critical in the induction of resistance to enzalutamide and abiraterone.
Armstrong, Cameron +4 more
core +1 more source
Animals, 2022 Our multicentric, masked, controlled and randomised study aimed to assess the efficacy and safety of Suprelorin® 4.7 mg (Virbac, Carros, France) regarding oestrus prevention in prepubertal intact bitches.
Aymeric Gontier +6 more
doaj +1 more source
Darolutamide in Nonmetastatic, Castration‐Resistant Prostate Cancer
New England Journal of Medicine, 2019 BACKGROUND Darolutamide is a structurally unique androgen‐receptor antagonist that is under development for the treatment of prostate cancer. We evaluated the efficacy of darolutamide for delaying metastasis and death in men with nonmetastatic ...
K. Fizazi +13 more
semanticscholar +1 more source