Results 81 to 90 of about 229,451 (392)

TheraP: a randomized phase 2 trial of 177Lu‐PSMA‐617 theranostic treatment vs cabazitaxel in progressive metastatic castration‐resistant prostate cancer (Clinical Trial Protocol ANZUP 1603)

open access: yesBJU International, 2019
To assess the activity and safety of cabazitaxel chemotherapy vs that of treatment with 177Lu‐PSMA‐617, a novel radiolabelled small molecule that binds with high affinity to prostate‐specific membrane antigen (PSMA), in men with metastatic castration ...
M. Hofman   +12 more
semanticscholar   +1 more source

Nanobody‐Decorated Lipid Nanoparticles for Enhanced mRNA Delivery to Tumors In Vivo

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents a targeted mRNA‐LNP platform engineered with anti‐PSMA nanobodies for prostate cancer therapy. Using different in vivo models, the authors demonstrate selective uptake and mRNA delivery in PSMA+ cancer cells. However, while targeting is enhanced, mRNA delivery efficacy is limited by tissue penetration, tumor necrosis, and immune ...
Pol Escudé Martinez de Castilla   +16 more
wiley   +1 more source

Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors

open access: yesCell Reports, 2015
Primary prostate cancer almost always has a luminal phenotype. However, little is known about the stem/progenitor properties of transformed cells within tumors.
Supreet Agarwal   +14 more
doaj   +1 more source

Different methods for laparoscopic castration in dogs [PDF]

open access: yesIraqi Journal of Veterinary Sciences, 2019
The aim of this study was to evaluate the different methods of performing a Laparoscopic castration in dogs and to determine the efficiency and disadvantages of each of these methods.
Tarek Al-Ukidi, Muneer S. Al-Badrany
doaj   +1 more source

The Castration Of Cryptorchids [PDF]

open access: yesJournal of Comparative Pathology and Therapeutics, 1889
n ...
openaire   +3 more sources

Advances and Strategies in Enhancing mRNA Cancer Vaccines

open access: yesAdvanced Materials, EarlyView.
Messenger RNA (mRNA) vaccines offer a powerful approach for cancer immunotherapy, but their clinical impact remains limited by delivery challenges and suboptimal immune activation. This review discusses key biological barriers and design strategies—including structural optimization, immunomodulation, organ targeting delivery, and advanced nanocarriers ...
Miao Zhang   +4 more
wiley   +1 more source

Castration of Sex Offenders: Indonesian Criminal Law Reform

open access: yesHasanuddin Law Review, 2019
The rise of cases of sexual violence today makes people become restless. This research is a normative legal research, where in this study the author analyzes various laws and regulations relating to sanctions for chemical castration in the perspective of
Irene Widiyaningrum   +3 more
doaj   +1 more source

Bull castration by method of total scrotal ablation [PDF]

open access: yesVeterinarski Glasnik, 2015
In this work, a 2 years and 10 months old bull, with 14 days history of wound on the right side of scrotum was presented. A painful swelling coated by grayish pseudo membranes of necrotic epithelium and fibrin was observed in right lateroventral
Smolec Ozren   +4 more
doaj   +1 more source

The molecular basis for ethnic variation and histological subtype differences in prostate cancer. [PDF]

open access: yes, 2013
Prostate cancer is a common malignancy among men in Western countries. Recently the morbidity and mortality of prostate cancer increase dramatically in several oriental countries including China.
Goldstein, Andrew S   +2 more
core   +1 more source

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