Clinical and Polysomnographic Comparison between Narcolepsy without Cataplexy and Idiopathic Hypersomnia [PDF]
Sleep Medicine Research, 2012 Background and Objective The aim of this study is to compare the clinical, electrophysiological (Polysomnography, PSG; Multiple Sleep Latency Test, MSLT) and biological data (HLA DQB1*0602 typing) in idiopathic hypersomnia with narcolepsy without ...
Tae Won Kim +7 more
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Scientific Reports, 2023 Cataplexy is one of the symptoms of type 1 narcolepsy, characterized by a sudden loss of muscle tone. It can be seen as a behavioral index of salience, predominantly positive emotion, since it is triggered by laughter in humans and palatable foods in ...
Shigetaka Kawashima +4 more
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Communications Biology, 2021 Kuwaki and Kanno examine courtship behavior in orexin neuron-ablated mice (ORX-AB), which are a model of narcolepsy/cataplexy. They find that ORX-AB mice showed cataplexy-like behavior during both dark and light periods in response to a female encounter,
Tomoyuki Kuwaki, Kouta Kanno
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Feasibility of following up gamma-hydroxybutyric acid concentrations in sodium oxybate (Xyrem®)-treated narcoleptic patients using dried blood spot sampling at home : an exploratory study [PDF]
, 2013 Background: Gamma-hydroxybutyric acid (GHB), well known as a party drug, especially in Europe, is also legally used (sodium oxybate, Xyrem (R)) to treat a rare sleep disorder, narcolepsy with cataplexy.
Hertegonne, Katrien +3 more
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Narcolepsy and emotional experience: a review of the literature [PDF]
, 2018 Narcolepsy is a chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. This disease affects significantly the overall patient functioning, interfering with social, work, and ...
De Gennaro, Luigi +4 more
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Activity dynamics of amygdala GABAergic neurons during cataplexy of narcolepsy
eLife, 2019 Recent studies showed activation of the GABAergic neurons in the central nucleus of the amygdala (CeA) triggered cataplexy of sleep disorder narcolepsy.
Ying Sun +5 more
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Etiopathogenesis and Neurobiology of Narcolepsy: A Review [PDF]
Journal of Clinical and Diagnostic Research, 2014 Narcolepsy is a chronic lifelong sleep disorder and it often leaves a debilitating effect on the quality of life of the sufferer. This disorder is characterized by a tetrad of excessive daytime sleepiness, cataplexy (brief loss of muscle tone following ...
Swarup Kumar, Haritha Sagili
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Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. [PDF]
, 2013 The neurochemical changes underlying human emotions and social behaviour are largely unknown. Here we report on the changes in the levels of two hypothalamic neuropeptides, hypocretin-1 and melanin-concentrating hormone, measured in the human amygdala ...
Behnke, Eric J +9 more
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The use of citalopram for the treatment of cataplexy
Sleep Science, 2014 This is a series of cases describing the use of citalopram for the treatment of cataplexy in patients with narcolepsy. Cataplexy is the most specific symptom of narcolepsy, being characterized by a sudden and temporary loss of muscle tonus, triggered by ...
Hassana de Almeida Fonseca +10 more
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Treatment dilemmas in a young man presenting with narcolepsy and psychotic symptoms. [PDF]
, 2011 Psychotic features can be present in both narcolepsy and psychosis, which can result in challenges in diagnosis and management. The prevalence of both conditions is low and the reports in young people are scarce. Our report illustrates the relevance of a
Davies, S, Fernandez, V, Walters, N
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