Results 21 to 30 of about 234,883 (311)

Maternal Wnt/β-catenin signaling coactivates transcription through NF-κB binding sites during Xenopus axis formation. [PDF]

, 2012
Maternal Wnt/β-Catenin signaling establishes a program of dorsal-specific gene expression required for axial patterning in Xenopus. We previously reported that a subset of dorsally expressed genes depends not only on Wnt/β-Catenin stimulation, but also ...
Rupp, Ralph A. W., Armstrong Neil J., Fagotto François, Christian Prothmann, Ralph A W Rupp, Prothmann, Christian, Neil J Armstrong, Rupp Ralph A. W., François Fagotto, Prothmann Christian, Fagotto, François, Armstrong, Neil J.   +11 more
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Silencing mutated β-catenin inhibits cell proliferation and stimulates apoptosis in the adrenocortical cancer cell line H295R [PDF]

, 2013
Adrenocortical carcinoma (ACC) is a rare and highly aggressive endocrine neoplasm, with limited therapeutic options. Activating β-catenin somatic mutations are found in ACC and have been associated with a poor clinical outcome. In fact, activation of the
Lucile Lefèvre, Ragazzon, Bruno, Constanze Hantel (280561), Guillaud-Bataille, Marine, Bruno Ragazzon (140444), Launay, Pierre, Stéphane Bonnet (280565), Marthe Rizk-Rabin (280575), Marine Guillaud-Bataille (9131), Karine Perlemoine, Lefèvre, Lucile, Sébastien Gaujoux (280559), Tissier, Frédérique, Hantel, Constanze, Frédérique Tissier (140448), Lucile Lefèvre (280570), Rizk-Rabin, Marthe, Karine Perlemoine (280567), Bertherat, Jérôme, Stéphane Bonnet, Bonnet, Stéphane, Sébastien Gaujoux, Perlemoine, Karine, Jérôme Bertherat, Bruno Ragazzon, Beuschlein, Felix, Marthe Rizk-Rabin, Frédérique Tissier, Pierre Launay (280563), Jérôme Bertherat (140471), Felix Beuschlein, Marine Guillaud-Bataille, Constanze Hantel, Felix Beuschlein (158361), Gaujoux, Sébastien, Pierre Launay   +35 more
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β-Catenin [PDF]

Journal of the American Society of Nephrology, 2011
Congenital anomalies of the kidney and urinary tract are the single most common cause of renal failure in childhood. Advances in the care of children with renal failure has primarily focused on optimizing the supportive, although nonspecific, treatment of chronic kidney disease and in addressing ...
Jacqueline Ho, Carlton M. Bates
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The CK1δ/ϵ-Tip60 Axis Enhances Wnt/β-Catenin Signaling via Regulating β-Catenin Acetylation in Colon Cancer

Frontiers in Oncology, 2022
Casein kinase 1δ/ϵ (CK1δ/ϵ) are well-established positive modulators of the Wnt/β-catenin signaling pathway. However, the molecular mechanisms involved in the regulation of β-catenin transcriptional activity by CK1δ/ϵ remain unclear.
Jiong Ning, Jiong Ning, Qi Sun, Zijie Su, Zijie Su, Lifeng Tan, Yun Tang, Sapna Sayed, Huan Li, Vivian Weiwen Xue, Shanshan Liu, Xianxiong Chen, Desheng Lu, Desheng Lu   +13 more
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Increased Expression of Adherens Junction Components in Mouse Liver following Bile Duct Ligation

Biomolecules, 2019
Adherens junctions, consisting of cadherins and catenins, are a group of cell-to-cell junctions that mediate mechanistic linkage between neighboring cells. By doing so, adherens junctions ensure direct intercellular contact and play an indispensable role
Raf Van Campenhout, Sara Crespo Yanguas, Axelle Cooreman, Eva Gijbels, Kaat Leroy, Vânia Vilas-Boas, Nick Devoogdt, Serge Muyldermans, Bruno Cogliati, Mathieu Vinken   +9 more
doaj   +1 more source

β-Catenin expression is associated with cell invasiveness in pancreatic cancer [PDF]

The Korean Journal of Internal Medicine, 2019
Background/Aims This study was tried to determine the role of β-catenin in invasion in pancreatic cancer. Methods We analyzed cancer invasiveness according to β-catenin expression in pancreatic cancer cell line.
Jin Niang Nan, Ok Ran Kim, Myung Ah Lee
doaj   +1 more source

Dissecting the impact of Frizzled receptors in Wnt/beta-catenin signaling of human mesenchymal stem cells [PDF]

, 2012
Wnt/beta-catenin signaling is of fundamental importance in the regulation of self-renewal, migration/invasion, and differentiation of human mesenchymal stem cells (hMSCs).
Ruiz-Heinrich, Lourdes, Peröbner, Iris, Capovilla, Simon, Neth, Peter, Fernsebner, Katharina, Lechner, F., Jochum, M., Neth, P., Kolben, Thomas, Geissler, Claudia, Fernsebner, K., Geissler, C., Perobner, I., Peroebner, Iris, Jochum, Marianne, Lechner, Felix, Ruiz-Heinrich, L., Kolben, T., Capovilla, S.   +18 more
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γ-Catenin at Adherens Junctions: Mechanism and Biologic Implications in Hepatocellular Cancer after β-Catenin Knockdown

Neoplasia: An International Journal for Oncology Research, 2013
β-Catenin is important in liver homeostasis as a part of Wnt signaling and adherens junctions (AJs), while its aberrant activation is observed in hepatocellular carcinoma (HCC).
Emily Diane Wickline, Yu Du, Donna B. Stolz, Michael Kahn, Satdarshan P.S. Monga   +4 more
doaj   +1 more source

Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural Stem cell specification into oligodendrocytes and glutamatergic neurons [PDF]

, 2014
In the postnatal and adult central nervous system (CNS), the subventricular zone (SVZ) of the forebrain is the main source of neural stem cells (NSCs) that generate olfactory neurons and oligodendrocytes (OLs), the myelinating cells of the CNS.
Raineteau, Olivier, Fischer, Bruno,, Sommer, Lukas, Sommer, Lukas,, Draganova, Kalina,, Draganova, Kalina, Fischer, Bruno, Cantu, Claudio, Azim, Kasum,, Butt, Arthur, Raineteau, Olivier,, Butt, Arthur,, Azim, Kasum, Hurtado-Chong, Anahi,, Hurtado-Chong, Anahi, Cantù, Claudio,, Zemke, Martina, Zemke, Martina,   +17 more
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Bowman's β-Catenin [PDF]

Journal of the American Society of Nephrology, 2012
Wnt/ β -catenin signaling plays a significant role during kidney development and maturation.[1][1][][2]–[3][3] β -Catenin, the canonical Wnt signal transducer, is involved in nephron induction[4][4],[5][5] and branching morphogenesis.[1][1],[6][6] Importantly, β -catenin modulation is ...
openaire   +2 more sources