Results 31 to 40 of about 10,779 (272)
γ-Catenin is overexpressed in acute myeloid leukemia and promotes the stabilization and nuclear localization of β-catenin [PDF]
, 2012 Canonical Wnt signaling regulates the transcription of T-cell factor (TCF)-responsive genes through the stabilization and nuclear translocation of the transcriptional co-activator, β-catenin.
A Gandillet +51 more
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Adherens junctions remain dynamic
BMC Biology, 2010 One of the four principal categories of cell-cell junctions that hold together and shape distinct tissues and organs in vertebrates, adherens junctions (AJs) form cell-cell contacts that connect transmembrane proteins with cytoskeletal actin filaments to
Falk Matthias M
doaj +1 more source
Loss of ctnnd2b affects neuronal differentiation and behavior in zebrafish
Frontiers in Neuroscience, 2023 Delta-catenin (CTNND2) is an adhesive junction associated protein belonging to the family of p120 catenins. The human gene is located on the short arm of chromosome 5, the region deleted in Cri-du-chat syndrome (OMIM #123450). Heterozygous loss of CTNND2
Raquel Vaz +5 more
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Silencing of Smed-βcatenin1 generates radial-like hypercephalized planarians [PDF]
, 2008 7 páginas, 4 figuras. Supplementary material for this article is available at http://dev.biologists.org/cgi/content/full/135/7/1215/DC1Little is known about the molecular mechanisms responsible for axis establishment during non-embryonic processes such ...
Adell, Teresa +3 more
core +1 more source
European Journal of Histochemistry, 2012 I am pretty sure that I don’t have to spend a single word to talk about the role played by tight junctions in biological processes and in keeping alive the cellular bases of life !
Carlo Alberto Redi
doaj +1 more source
NDRG2 Regulates the Expression of Genes Involved in Epithelial Mesenchymal Transition of Prostate Cancer Cells [PDF]
Iranian Journal of Medical Sciences, 2019 Background: Metastasis is the main cause of prostate cancer (PCa) death. The inhibitory effect of N-myc downstream-regulated gene 2 (NDRG2) on the invasiveness properties of PCa cells has been demonstrated previously.
Mohammad Moradi Monfared +5 more
doaj +1 more source
E-cadherin and cell adhesion: a role in architecture and function in the pancreatic islet [PDF]
, 2007 Background/Aims: The efficient secretion of insulin from beta-cells requires extensive intra-islet communication. The cell surface adhesion protein epithelial (E)-cadherin (ECAD) establishes and maintains epithelial tissues such as the islets of ...
Bamji SX +21 more
core +1 more source
Frontiers in Neuroscience, 2015 In the adult the interface between the cerebrospinal fluid (CSF) and the brain is lined by the ependymal cells, which are joined by gap junctions. These intercellular connections do not provide a diffusional restrain between the two compartments. However
Norman Ruthven Saunders +8 more
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New functions for alpha-catenins in health and disease: from cancer to heart regeneration. [PDF]
, 2015 Strong cell-cell adhesion mediated by adherens junctions is dependent on anchoring the transmembrane cadherin molecule to the underlying actin cytoskeleton.
Li, Jifen +2 more
core +2 more sources
Brazilian Journal of BiologyCell adhesion molecules act as signal transducers from the extracellular environment to the cytoskeleton and the nucleus and consequently induce changes in the expression pattern of structural proteins.
MF. Izaguirre +4 more
doaj +1 more source