A Catharanthus roseus mutant with trace levels of secologanin and monoterpenoid indole alkaloids does not express BIS1/BIS2 transcription factors and fails to activate iridoid biosynthesis. [PDF]
The Madagascar periwinkle (Catharanthus roseus) is the sole source of the monoterpenoid indole alkaloids (MIAs) that result in several essential anti-cancer chemotherapies as well as being an important source for other MIA derived pharmaceutical agents ...
Kidd, Trevor
core +1 more source
Catharanthus roseus produces pharmacologically relevant terpenoid indole alkaloids (TIAs), including vinblastine (VLB) and vincristine (VCR). However, their low natural abundance makes it essential to optimize C.
Marisa S.C. Lourenço +4 more
doaj +1 more source
The biosynthesis of monoterpenoid indole alkaloids from strictosidine [PDF]
Nagakura, Naotaka +2 more
core +1 more source
Development of an efficient Agrobacterium-mediated transformation method and its application in tryptophan pathway modification in Catharanthus roseus. [PDF]
Kisaka H +6 more
europepmc +1 more source
Eredmények a természetes szerves anyagok kutatásában. Új, daganatellenes hatású Vinca alkaloid származékok előállítása és flavon alkaloidok szintézise [PDF]
Bölcskei, Hedvig +4 more
core +1 more source
Coronaridine congeners decrease neuropathic pain in mice and inhibit α9α10 nicotinic acetylcholine receptors and CaV2.2 channels [PDF]
Adams, D. J. +6 more
core +1 more source
Advances in Metabolic Engineering of Plant Monoterpene Indole Alkaloids. [PDF]
Salim V, Jarecki SA, Vick M, Miller R.
europepmc +1 more source
De novo biosynthesis of a vinblastine precursor in Pichia pastoris. [PDF]
Yu J, Lv D, Zhang L.
europepmc +1 more source
Partial purification and properties of (S)-norlaudanosoline synthase from Eschscholtzia tenuifolia cell cultures [PDF]
Nagakura, Naotaka +3 more
core +1 more source
Protein-Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis. [PDF]
Carr SC +5 more
europepmc +1 more source

