Results 101 to 110 of about 1,359 (207)

New Insights into the Mechanism and an Expanded Scope of the Fe(III)-Mediated Vinblastine Coupling Reaction

, 2016
A definition of the scope of aromatic substrates that participate with catharanthine in an Fe­(III)-mediated coupling reaction, an examination of the key structural features of catharanthine required for participation in the reaction, and the development
Dale L. Boger (1306542), Hiroaki Gotoh (1771738), Albert Eschenmoser (1964986), Justin E. Sears (1491019)   +3 more
core   +1 more source

Context matters: Photoperiodic light spectrum modulates UV-A-induced alkaloid profile and oxidative signaling in Catharanthus roseus

Scientia Horticulturae
Catharanthus roseus produces pharmacologically relevant terpenoid indole alkaloids (TIAs), including vinblastine (VLB) and vincristine (VCR). However, their low natural abundance makes it essential to optimize C.
Marisa S.C. Lourenço, Andreia Garrido, Victor A.P. Freitas, Ep Heuvelink, Susana M.P. Carvalho   +4 more
doaj   +1 more source

Regulation of secondary metabolism in higher plants. Effect of alkaloids on a cytochrome P-450 dependent monooxygenase

, 1975
An end-product indole alkaloid, catharanthine, inhibits a membrane-bound cytochrome P-450 dependent monooxygenase of the higher plant, Vinca rosea. Kinetic analysis revealed the alkaloid to be a reversible, linear, non-competitive inhibitor (Ki=1 mM ...
Madyastha, K. M., McFarlane, John, Coscia, Carmine J.   +2 more
core   +1 more source

Assembly and analysis of stephania japonica mitochondrial genome provides new insights into its identification and energy metabolism

BMC Genomics
Stephania japonica, a popular indoor ornamental and medicinal plant widely found in southern China, contains many natural compounds with potential medicinal value. S.
Ya Wu, Zhihao Sun, Zhaoyu Liu, Ting Qiu, Xiaojing Li, Liang Leng, Shilin Chen   +6 more
doaj   +1 more source

The chemistry of the Vinca alkaloids sitsirikine, catharanthine, and their derivatives

, 1964
In part I of this thesis are described the structural determinations of sitsirikine, dihydrositsirikine and isositsirikine, three new alkaloids from Vinca rosea Linn.
Brown, Richard Talbot
core  

CrLHP1-CrJAZ1 Module Regulates Monoterpenoid Indole Alkaloid Biosynthesis via JA Signaling in <i>Catharanthus roseus</i>. [PDF]

Genes (Basel)
Yang B, Ma W, Cheng J, Gao X, Yu F.
europepmc   +1 more source

Development of an efficient Agrobacterium-mediated transformation method and its application in tryptophan pathway modification in Catharanthus roseus. [PDF]

Plant Biotechnol (Tokyo), 2023
Kisaka H, Chin DP, Miwa T, Hirano H, Uchiyama S, Mii M, Iyo M.   +6 more
europepmc   +1 more source

Advances in Metabolic Engineering of Plant Monoterpene Indole Alkaloids. [PDF]

Biology (Basel), 2023
Salim V, Jarecki SA, Vick M, Miller R.
europepmc   +1 more source

Tuning reductase activity in monoterpene indole alkaloid biosynthesis. [PDF]

Proc Natl Acad Sci U S A
Carr SC, Wu S, Gase K, Nakamura Y, Kamileen MO, Kunert M, Heinicke S, Kang M, Grabe V, Caputi L, O'Connor SE.   +10 more
europepmc   +1 more source

Protein-Protein Interactions Modulate a Key Branch Point in Monoterpene Indole Alkaloid Biosynthesis. [PDF]

ACS Chem Biol
Carr SC, McDonald A, Langley C, Grabe V, Gase K, O'Connor SE.   +5 more
europepmc   +1 more source