Results 61 to 70 of about 1,103 (171)

Structure and Synthesis of Vindolicine and Derivatives

Chemistry &Biodiversity, Volume 21, Issue 4, April 2024.
Abstract This article describes the reaction of vindoline with formaldehyde and trimethyl orthoformate to prepare vindolicine, tris‐vindolicinyl methane and higher molecular weight homologues. The synthesis of 10‐formyl vindoline as an intermediate allowed further exploration of its chemistry, in particular the reaction with acetone which yielded a ...
Asia, Yousuf Sammer, Laure Vendier, Georges Massiot   +3 more
wiley   +1 more source

Jasmonic Acid Effect on the Fatty Acid and Terpenoid Indole Alkaloid Accumulation in Cell Suspension Cultures of Catharanthus roseus

Molecules, 2014
The stress response after jasmonic acid (JA) treatment was studied in cell suspension cultures of Catharanthus roseus. The effect of JA on the primary and secondary metabolism was based on changes in profiles of fatty acids (FA) and terpenoid indole ...
Guitele Dalia Goldhaber-Pasillas, Natali Rianika Mustafa, Robert Verpoorte   +2 more
doaj   +1 more source

CrERF5, an AP2/ERF Transcription Factor, Positively Regulates the Biosynthesis of Bisindole Alkaloids and Their Precursors in Catharanthus roseus

Frontiers in Plant Science, 2019
Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor effects and widely used in clinical treatment.
Qifang Pan, Chenyi Wang, Zhiwei Xiong, Hang Wang, Xueqing Fu, Qian Shen, Bowen Peng, Yanan Ma, Xiaofen Sun, Kexuan Tang   +9 more
doaj   +1 more source

Optimization of 3', 4'-Anhydrovinblastine Synthesis Using Crude Extracts of Irradiated with Near-Ultraviolet Light

Natural Product Communications, 2016
Dimeric indole alkaloids (DIAs), such as vinblastine and vincristine, found in Catharanthus roseus are used clinically as antitumor drugs. A stable supply of DIAs is desired because these alkaloids are very expensive due to their low abundance in plants.
Mamiko Asano, Kazuo Harada, Akiko Umeno, Kazumasa Hirata   +3 more
doaj   +1 more source

Bioengineered Indoor Farming Approaches: LED Light Spectra and Biostimulants for Enhancing Vindoline and Catharanthine Production in Catharanthus roseus

Horticulturae
Light quality and biostimulants regulate alkaloid biosynthesis and promote plant growth, but their combined effects on vindoline (VDL) and catharanthine (CAT) production in Catharanthus roseus remain underexplored.
Alessandro Quadri, Bianca Sambuco, Mattia Trenta, Patrizia Tassinari, Daniele Torreggiani, Laura Mercolini, Michele Protti, Alessandra Zambonelli, Federico Puliga, Alberto Barbaresi   +9 more
doaj   +1 more source

Enhancement of vindoline and catharanthine production in Catharanthus roseus by LED light and plasma activated water.

PLoS ONE
This study aimed to increase the concentrations of vindoline (VDL) and catharanthine (CAT) in Catharanthus roseus plants cultivated in an indoor farming system using artificial lighting and plasma-activated water (PAW).
Alessandro Quadri, Alberto Barbaresi, Patrizia Tassinari, Assunta Bertaccini, Nicoletta Contaldo, Laura Mercolini, Michele Protti, Roberto Montalbetti, Romolo Laurita, Daniele Torreggiani   +9 more
doaj   +1 more source

In Silico Evaluation of Pharmacokinetics and Toxicity Profile of AlkaloidsPresent in Leaves of Catharanthus roseus L.

RGUHS Journal of Pharmaceutical Sciences
Background Catharanthus roseus Madagascar periwinkle is a well-known medicinal plant that produces a variety of alkaloids with significant pharmacological activities particularly in cancer and diabetes treatment.Aim This study aimed ...
Ramgopal M Dhanwad, Usha R, Ganesh S
doaj   +1 more source

Comprehensive analysis of SPL gene family and miR156a/SPLs in the regulation of terpenoid indole alkaloid biosynthesis in Catharanthus roseus L

BMC Plant Biology
Background Catharanthus roseus (C. roseus), belongs to the dogbane family Apocynaceae, is the source of various terpenoid indole alkaloids (TIAs) with excellent antitumor properties, including vinblastine, vincristine, ajmalicine, serpentine, vindoline ...
Yaojie Zhang, Xiaofan Ni, Xueqing Fu, Ayat Taheri, Wei Zhang, Pin Liu, Hang Liu, Ling Li, Yuliang Wang, Kexuan Tang   +9 more
doaj   +1 more source

Assembly and analysis of stephania japonica mitochondrial genome provides new insights into its identification and energy metabolism

BMC Genomics
Stephania japonica, a popular indoor ornamental and medicinal plant widely found in southern China, contains many natural compounds with potential medicinal value. S.
Ya Wu, Zhihao Sun, Zhaoyu Liu, Ting Qiu, Xiaojing Li, Liang Leng, Shilin Chen   +6 more
doaj   +1 more source

CrLHP1-CrJAZ1 Module Regulates Monoterpenoid Indole Alkaloid Biosynthesis via JA Signaling in <i>Catharanthus roseus</i>. [PDF]

Genes (Basel)
Yang B, Ma W, Cheng J, Gao X, Yu F.
europepmc   +1 more source