Results 61 to 70 of about 1,989 (164)
Plants, 2022 Catharanthus roseus synthesizes bioactive therapeutic metabolites, known as monoterpenoid indole alkaloids (MIAs), including antineoplastic vinblastine and vincristine, which have high global demand, and antihypertensive ajmalicine, a serpentine. However,
Vyoma Mistry +5 more
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Novel Biocatalysts from Specialized Metabolism
Angewandte Chemie, Volume 136, Issue 4, January 22, 2024.Enzymes are increasingly valuable as biocatalysts in synthetic chemistry. Many novel biocatalysts have emerged from the study of secondary metabolism, where rare and unusual reactions take place. In this review, we explore biocatalysts that address various synthetic challenges, including cyclization, C−H functionalization, and cross‐coupling, among ...
Hajo Kries +2 more
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Molecules, 2012 In the present study, an improved method termed negative-pressure cavitation extraction (NPCE) followed by reverse phase high-performance liquid chromatography (RP-HPLC) was developed for the extraction and quantification of vindoline (VDL ...
Yuangang Zu +6 more
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Acetylation‐Deacetylation‐Driven Natural Product Biosynthesis
ChemistryEurope, Volume 3, Issue 4, July 14, 2025.This review summarizes the role of acetylation‐deacetylation in natural product biosynthesis, including acetylation followed by deacetylation after several biosynthetic steps, acetylation‐mediated rearrangement, acetylation‐triggered elimination, and the acetylation cycle as a regulatory mechanism. These processes are vital for the formation of complex
Huibin Wang, Ikuro Abe
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Do Fungicides Affect Alkaloid Production in Catharanthus roseus (L.) G. Don. Seedlings?
Molecules, 2023 The presence of endophytes in plants is undeniable, but how significant their involvement is in the host plant biosynthetic pathways is still unclear. The results reported from fungicide treatments in plants varied. Fungicide treatment in Taxus was found
Purin Candra Purnama +2 more
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In vitro growth and content of vincristine and vinblastine of Catharanthus roseus L. hairy roots in response to precursors and elicitors [PDF]
, 2022 Catharanthus roseus L. is a medicinal plant that produces numerous indole terpenoid alkaloids, including vincristine and vinblastine, which are used for cancer treatment.
Bui, Anh Lan +5 more
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Binary Stress Induces an Increase in Indole Alkaloid Biosynthesis in Catharanthus roseus
Frontiers in Plant Science, 2015 Catharanthus roseus is an important medicinal plant, which produces a variety of indole alkaloids of significant pharmaceutical relevance. In the present study, we aimed to investigate the potential stress-induced increase of indole alkaloid biosynthesis
Wei eZhu +5 more
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First genomic insights into the Mandevilla genus
Frontiers in Plant Science, 2022 Mandevilla (Apocynaceae) is a greatly appreciated genus in the world ornamental market. In this study, we attempted to address the poor genetic knowledge and the huge taxonomic gaps existing in this genus by analyzing a collection of 55 accessions. After
Fabio Palumbo +6 more
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Plant cell culture technology in the cosmetics and food industries : current state and future trends [PDF]
, 2018 The production of drugs, cosmetics, and food which are derived from plant cell and tissue cultures has a long tradition. The emerging trend of manufacturing cosmetics and food products in a natural and sustainable manner has brought a new wave in plant ...
A Barbulova +109 more
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New Phytologist, Volume 245, Issue 1, Page 347-362, January 2025.Summary In plants, the biosynthetic pathways of some specialized metabolites are partitioned into specialized or rare cell types, as exemplified by the monoterpenoid indole alkaloid (MIA) pathway of Catharanthus roseus (Madagascar Periwinkle), the source of the anticancer compounds vinblastine and vincristine. In the leaf, the C.
Chenxin Li +8 more
wiley +1 more source