Results 61 to 70 of about 1,070 (170)

Structure and Synthesis of Vindolicine and Derivatives

Chemistry &Biodiversity, Volume 21, Issue 4, April 2024.
Abstract This article describes the reaction of vindoline with formaldehyde and trimethyl orthoformate to prepare vindolicine, tris‐vindolicinyl methane and higher molecular weight homologues. The synthesis of 10‐formyl vindoline as an intermediate allowed further exploration of its chemistry, in particular the reaction with acetone which yielded a ...
Asia, Yousuf Sammer, Laure Vendier, Georges Massiot   +3 more
wiley   +1 more source

Boosting Sensitivity in Liquid Chromatography–Fourier Transform Ion Cyclotron Resonance–Tandem Mass Spectrometry for Product Ion Analysis of Monoterpene Indole Alkaloids

Frontiers in Plant Science, 2015
In metabolomics, the analysis of product ions in tandem mass spectrometry (MS/MS) is noteworthy to chemically assign structural information. However, the development of relevant analytical methods are less advanced.
Ryo eNakabayashi, Hiroshi eTsugawa, Mariko eKitajima, Hiromitsu eTakayama, Kazuki eSaito, Kazuki eSaito   +5 more
doaj   +1 more source

Chromium-induced alkaloid production in Catharanthus roseus (L.) G.Don in vitro cultured shoots and related gene expression patterns particularly for the novel gene GS

Acta Agriculturae Slovenica, 2019
This study aimed to determine the effects of methyl jasmonate (Mj) combined with chromium (Cr) as elicitor on production of medicinal alkaloids, its antioxidant potential, and its effects on the expression of signaling and biosynthetic enzymes.
Elham KHATAEE, Farah KARIMI, Khadijeh RAZAVI   +2 more
doaj   +1 more source

Jasmonic Acid Effect on the Fatty Acid and Terpenoid Indole Alkaloid Accumulation in Cell Suspension Cultures of Catharanthus roseus

Molecules, 2014
The stress response after jasmonic acid (JA) treatment was studied in cell suspension cultures of Catharanthus roseus. The effect of JA on the primary and secondary metabolism was based on changes in profiles of fatty acids (FA) and terpenoid indole ...
Guitele Dalia Goldhaber-Pasillas, Natali Rianika Mustafa, Robert Verpoorte   +2 more
doaj   +1 more source

CrERF5, an AP2/ERF Transcription Factor, Positively Regulates the Biosynthesis of Bisindole Alkaloids and Their Precursors in Catharanthus roseus

Frontiers in Plant Science, 2019
Catharanthus roseus contains a variety of monoterpenoid indole alkaloids (MIAs), among which bisindole alkaloids vinblastine and vincristine are well-known to have antitumor effects and widely used in clinical treatment.
Qifang Pan, Chenyi Wang, Zhiwei Xiong, Hang Wang, Xueqing Fu, Qian Shen, Bowen Peng, Yanan Ma, Xiaofen Sun, Kexuan Tang   +9 more
doaj   +1 more source

Optimization of 3', 4'-Anhydrovinblastine Synthesis Using Crude Extracts of Irradiated with Near-Ultraviolet Light

Natural Product Communications, 2016
Dimeric indole alkaloids (DIAs), such as vinblastine and vincristine, found in Catharanthus roseus are used clinically as antitumor drugs. A stable supply of DIAs is desired because these alkaloids are very expensive due to their low abundance in plants.
Mamiko Asano, Kazuo Harada, Akiko Umeno, Kazumasa Hirata   +3 more
doaj   +1 more source

Bioengineered Indoor Farming Approaches: LED Light Spectra and Biostimulants for Enhancing Vindoline and Catharanthine Production in Catharanthus roseus

Horticulturae
Light quality and biostimulants regulate alkaloid biosynthesis and promote plant growth, but their combined effects on vindoline (VDL) and catharanthine (CAT) production in Catharanthus roseus remain underexplored.
Alessandro Quadri, Bianca Sambuco, Mattia Trenta, Patrizia Tassinari, Daniele Torreggiani, Laura Mercolini, Michele Protti, Alessandra Zambonelli, Federico Puliga, Alberto Barbaresi   +9 more
doaj   +1 more source

Organic N-fertilizer, rhizobacterial inoculation and fungal compost improve nutrient uptake, plant growth and the levels of vindoline, ajmalicine, vinblastine, catharanthine and total alkaloids in Catharanthus roseus L.

Folia Horticulturae, 2018
The aim of the study was to replace mineral fertilizers with organic and biological fertilizers to improve nutrient uptake, plant growth and the concentrations of some important secondary metabolites in periwinkle (Catharanthus roseus L.).
Hashemabadi Davood, Sabzevari Fatemeh, Kaviani Behzad, Ansari Mohammad Hossein   +3 more
doaj   +1 more source

In Silico Evaluation of Pharmacokinetics and Toxicity Profile of AlkaloidsPresent in Leaves of Catharanthus roseus L.

RGUHS Journal of Pharmaceutical Sciences
Background Catharanthus roseus Madagascar periwinkle is a well-known medicinal plant that produces a variety of alkaloids with significant pharmacological activities particularly in cancer and diabetes treatment.Aim This study aimed ...
Ramgopal M Dhanwad, Usha R, Ganesh S
doaj   +1 more source

Assembly and analysis of stephania japonica mitochondrial genome provides new insights into its identification and energy metabolism

BMC Genomics
Stephania japonica, a popular indoor ornamental and medicinal plant widely found in southern China, contains many natural compounds with potential medicinal value. S.
Ya Wu, Zhihao Sun, Zhaoyu Liu, Ting Qiu, Xiaojing Li, Liang Leng, Shilin Chen   +6 more
doaj   +1 more source