Results 31 to 40 of about 52,950,106 (199)

Cathelicidin, vitamin D3 dan imunitas terhadap tuberkulosis

JKS (Jurnal Kedokteran Syiah Kuala), 2020
Abstrak. Tuberkulosis (TB) merupakan salah satu penyakit infeksi yang menjadi masalah di dunia. Risiko untuk mendapatkan infeksi TB dipengaruhi oleh imunitas alamiah melawan mikobakteria.
Yunita Arliny, Maryatun Hasan
doaj   +1 more source

A Novel Biological Role for Peptidyl-Arginine Deiminases: Citrullination of Cathelicidin LL-37 Controls the Immunostimulatory Potential of Cell-Free DNA. [PDF]

J Immunol, 2018
LL-37, the only human cathelicidin that is released during inflammation, is a potent regulator of immune responses by facilitating delivery of oligonucleotides to intracellular TLR-9, thereby enhancing the response of human plasmacytoid dendritic cells ...
Wong A, Bryzek D, Dobosz E, Scavenius C, Svoboda P, Rapala-Kozik M, Lesner A, Frydrych I, Enghild J, Mydel P, Pohl J, Thompson PR, Potempa J, Koziel J.   +13 more
europepmc   +2 more sources

Circulating cathelicidin levels correlate with mucosal disease activity in ulcerative colitis, risk of intestinal stricture in Crohn’s disease, and clinical prognosis in inflammatory bowel disease

BMC Gastroenterology, 2017
Background Cathelicidin (LL-37) is an antimicrobial peptide known to be associated with various autoimmune diseases. We attempt to determine if cathelicidin can accurately reflect IBD disease activity.
Diana Hoang-Ngoc Tran, Jiani Wang, Christina Ha, Wendy Ho, S. Anjani Mattai, Angelos Oikonomopoulos, Guy Weiss, Precious Lacey, Michelle Cheng, Christine Shieh, Caroline C. Mussatto, Samantha Ho, Daniel Hommes, Hon Wai Koon   +13 more
doaj   +1 more source

Impact of vitamin D status and cathelicidin antimicrobial peptide on adults with active pulmonary TB globally: A systematic review and meta-analysis.

PLoS ONE, 2021
BackgroundTuberculosis remains a global threat and a public health problem that has eluded attempts to eradicate it. Low vitamin D levels have been identified as a risk factor for tuberculosis infection and disease.
Ester Lilian Acen, Irene Andia Biraro, William Worodria, Moses L Joloba, Bill Nkeeto, Joseph Musaazi, David Patrick Kateete   +6 more
doaj   +1 more source

Endopeptidase O promotes Streptococcus suis immune evasion by cleaving the host- defence peptide cathelicidins

Virulence, 2023
Streptococcus suis is a zoonotic Gram-positive bacterium that causes invasive infections such as sepsis and meningitis, threatening public health worldwide.
Mingjie Jin, Siyu Liang, Jing Wang, Huihui Zhang, Yueling Zhang, Wanjiang Zhang, Siguo Liu, Fang Xie   +7 more
doaj   +1 more source

Pulmonary defense and the human cathelicidin hCAP-18/LL-37 [PDF]

Immunologic Research, 2005
Antimicrobial peptides form an important component of the innate immune system. The cathelicidin family, a key member of the antimicrobial peptide defenses, has been highly conserved throughout evolution. Though widespread in mammals, there is currently only one identified human example, hCAP-18/LL-37. The cathelicidins have been found to have multiple
Fahy, R. J., Wewers, M. D.
openaire   +2 more sources

Snake Cathelicidin NA-CATH and Smaller Helical Antimicrobial Peptides Are Effective against Burkholderia thailandensis. [PDF]

PLoS Neglected Tropical Diseases, 2015
Burkholderia thailandensis is a Gram-negative soil bacterium used as a model organism for B. pseudomallei, the causative agent of melioidosis and an organism classified category B priority pathogen and a Tier 1 select agent for its potential use as a ...
Ryan J Blower, Stephanie M Barksdale, Monique L van Hoek   +2 more
doaj   +1 more source

Serum level of the human antimicrobial cathelicidin (hCAP18/LL-37) in patients with psoriasis vulgaris [PDF]

, 2016
Introduction: Psoriasis is a chronic immune-mediated inflammatory disease. Human cathelicidin (hCAP18/LL37) has been elucidated recently as a modulator of inflammation in the affected skin.
Chervenkov, Trifon Georgiev, Gerova, Daniela Ivanova, Pavlov, Stoyan Ivanov; Clinic of Dermatology and Venereology, Ivanova, Irina Ivanova, Balev, Svetlozar Petrov   +4 more
core   +5 more sources

Chronic Ethanol Exposure Effects on Vitamin D Levels among Subjects with Alcohol Use Disorder

Environmental Health Insights, 2016
Vitamin D has been previously recognized to play important roles in human immune system and function. In the pulmonary system, vitamin D regulates the function of antimicrobial peptides, especially cathelicidin/LL-37.
Olalekan Ogunsakin, Tete Hottor, Ashish Mehta, Maureen Lichtveld, Michael McCaskill   +4 more
doaj   +1 more source

Cathelicidins—Therapeutic antimicrobial and antitumor host defense peptides for oral diseases

Japanese Dental Science Review, 2011
The oral epithelium functions as a mechanical and protective barrier to resist bacterial infection. Several types of host defense peptides (HDPs), including defensins, cathelicidins, and histatins, may have important roles in innate host defense.
Kazuhiko Okumura
doaj   +1 more source