Results 21 to 30 of about 191,378 (381)

Peptide synthesis by recombinant Fasciola hepatica cathepsin L1 [PDF]

open access: yes, 2006
Synthesis of the tripeptide Z-Phe-Arg-SerNH2 has been accomplished by a recombinant cysteine protease, cathepsin L1 from liver fluke (Fasciola hepatica), using Z-Phe-Arg-OMe as acyl acceptor and SerNH2 as nucleophile in 0.1 M ammonium acetate pH 9.0–12.5%
Ciarán Ó'Fágáin   +16 more
core   +1 more source

Muscle Quality of Sword Prawn (Parapenaeopsis hardwickii) during Cold Storage Based on Changes of Endogenous Enzyme Activity

open access: yesShipin gongye ke-ji, 2022
Objective: To investigate the changes of endogenous enzyme activity and muscle quality characteristics of Sword prawn (Parapenaeopsis hardwickii) under cold storage. Methods: Sword prawn (Parapenaeopsis hardwickii) was taken as the research object.
Ting ZHOU   +5 more
doaj   +1 more source

Importance of lysosomal cysteine proteases in lung disease

open access: yesRespiratory Research, 2000
The human lysosomal cysteine proteases are a family of 11 proteases whose members include cathepsins B, C, H, L, and S. The biology of these proteases was largely ignored for decades because of their lysosomal location and the belief that their function ...
Chapman Harold A, Wolters Paul J
doaj   +1 more source

Toxoplasma Cathepsin Protease B and Aspartyl Protease 1 Are Dispensable for Endolysosomal Protein Digestion

open access: yesmSphere, 2020
The lysosome-like vacuolar compartment (VAC) is a major site of proteolysis in the intracellular parasite Toxoplasma gondii. Previous studies have shown that genetic ablation of a VAC-residing cysteine protease, cathepsin protease L (CPL), resulted in ...
Christian McDonald   +5 more
doaj   +1 more source

Neutrophil Extracellular Traps Induce Endothelial Cell Activation and Tissue Factor Production Through Interleukin-1&agr; and Cathepsin G

open access: yesArteriosclerosis, Thrombosis and Vascular Biology, 2018
Objective— Coronary artery thrombosis can occur in the absence of plaque rupture because of superficial erosion. Erosion-prone atheromata associate with more neutrophil extracellular traps (NETs) than lesions with stable or rupture-prone characteristics.
E. Folco   +9 more
semanticscholar   +1 more source

TNF Family Cytokines Induce Distinct Cell Death Modalities in the A549 Human Lung Epithelial Cell Line when Administered in Combination with Ricin Toxin

open access: yesToxins, 2019
Ricin is a member of the ribosome-inactivating protein (RIP) family of toxins and is classified as a biothreat agent by the Centers for Disease Control and Prevention (CDC).
Alexa L. Hodges   +5 more
doaj   +1 more source

The role of lysosomal peptidases in glioma immune escape: underlying mechanisms and therapeutic strategies

open access: yesFrontiers in Immunology, 2023
Glioblastoma is the most common primary malignant tumor of the central nervous system, which has the characteristics of strong invasion, frequent recurrence, and rapid progression.
Hao Liu   +19 more
doaj   +1 more source

Patterns of gene expression in schistosomes: localization by whole mount in situ hybridization [PDF]

open access: yes, 2007
rom the identification of genes to the characterization of their functions and interactions. Developmental biologists have long used whole mount in situ hybridization (WISH) to determine gene expression patterns, as a vital tool for formulating and ...
Davis   +7 more
core   +1 more source

Microglial cathepsin B as a key driver of inflammatory brain diseases and brain aging

open access: yesNeural Regeneration Research, 2019
Interleukin-1β is a potent proinflammatory cytokine that plays a key role in the pathogenesis of the brain aging and diverse range of neurological diseases including Alzheimer’s disease, Parkinson’s disease, stroke and persistent pain.
H. Nakanishi
semanticscholar   +1 more source

Gallic Acid Reduces Experimental Colitis in Rats by Downregulation of Cathepsin and Oxidative Stress

open access: yesErciyes Medical Journal, 2020
Objective: Ulcerative colitis (UC) is an idiopathic inflammatory bowel disease (IBD) with common, repetitive inflammation of the colon and rectum, which is highly defined by loss of blood on colon mucosa, ulceration and acute inflammation.
Gökhan Bayramoğlu   +6 more
doaj   +1 more source

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