Results 1 to 10 of about 19,218 (96)

Human cathepsin H [PDF]

Biochemical Journal, 1980
Cathepsin H was purified from human liver by a method involving autolysis and acetone fractionation, and chromatography on DEAE-cellulose, Ultrogel AcA 54, hydroxyapatite and concanavalin A-Sepharose. The procedure allowed for the simultaneous isolation of cathepsin B and cathepsin D. Cathepsin H was shown to consist of a single polypeptide chain of 28
W N, Schwartz, A J, Barrett
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Human cathepsin D.

Folia Histochemica et Cytobiologica, 2008
A literature survey was performed of human cathepsin D gene, cathepsin D biosynthesis, posttranslatory modifications, transport within the cell, substrate specificity and catalytic effect. Methods used to determine the activity and level of this proteinase as well as its role in the biochemistry and pathobiochemistry of cells, tissues and organs were ...
Marek Gacko, Alina Minarowska, Alicja Karwowska, Łukasz Minarowski   +3 more
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New Functional Aspects of Cathepsin D and Cathepsin E

Molecules and Cells, 2000
Cathepsin D (CD) and cathepsin E are representative lysosomal and nonlysosomal aspartic proteinases, respectively, and play an important role in the degradation of proteins, the generation of bioactive proteins, antigen processing, etc. Recenty, several lines of evidence have suggested the involvement of these two enzymes in the execution of neuronal ...
T, Tsukuba, K, Okamoto, Y, Yasuda, W, Morikawa, H, Nakanishi, K, Yamamoto   +5 more
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Cathepsin D inhibitors.

Folia histochemica et cytobiologica, 2007
Inhibitors of cathepsin D belong to chemical compounds that estrify carboxyl groups of the Asp33 and Asp231 residues of its catalytic site, penta-peptides containing statin, i.e. the amino acid similar in structure to the tetraedric indirect product, and polypeptides found in the spare organs of many plants and forming permanent noncovalent complexes ...
M. Gacko, A. Minarowska, A. Karwowska,, Ł. Minarowski   +3 more
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Cathepsin B And Cathepsin L.

NIPPON SUISAN GAKKAISHI, 1996
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Cathepsin H as a causal risk factor and therapeutic target in proliferative diabetic retinopathy. [PDF]

J Transl Med
Zhou Q, Yang F, Guo S, Zhou X, Jiang F, Li Z, Li X, Zhao Y, Lai Y, Gong H, Lan Y.   +10 more
europepmc   +1 more source

The causal relationship between cathepsins and ankylosing spondylitis: a two-sample Mendelian randomization study. [PDF]

Ther Adv Musculoskelet Dis
Wu B, Li R, Li J, An Q, Jin S, Liu Q, Zhang Y, Liu Y.   +7 more
europepmc   +1 more source

A two-sample Mendelian randomization study and mediation analysis exploring the link between cathepsins and epilepsy. [PDF]

Epilepsia Open
Sun H, Ma D, Zhang W, Hou S, Chen Z, Li X, Meng H, Zhang D.   +7 more
europepmc   +1 more source

Shaping the Immune Response: Cathepsins in Virus-Dendritic Cell Interactions. [PDF]

Cells
Niedzielska A, Bossowska-Nowicka M, Biernacka Z, Gregorczyk-Zboroch K, Toka FN, Szulc-Dąbrowska L.   +5 more
europepmc   +1 more source

The protease cathepsin K can debulk the cancer glycocalyx. [PDF]

J Biol Chem
Kuo A, Tender GS, Chow WD, Riley NM, Wen KC, Park S, Paek JH, Roberts DS, Peltan EL, Paszek MJ, Bertozzi CR.   +10 more
europepmc   +1 more source