Results 21 to 30 of about 20,584 (256)
Frontiers in Medicine, 2017 AimWe have previously demonstrated the putative presence of two cancer stem cell (CSC) subpopulations within moderately differentiated oral tongue squamous cell carcinoma (MDOTSCC), which express components of the renin–angiotensin system (RAS).
Therese Featherston +7 more
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Cysteine Cathepsins and Their Extracellular Roles: Shaping the Microenvironment
Cells, 2019 For a long time, cysteine cathepsins were considered primarily as proteases crucial for nonspecific bulk proteolysis in the endolysosomal system. However, this view has dramatically changed, and cathepsins are now considered key players in many important
Eva Vidak +3 more
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Redundancy between Cysteine Cathepsins in Murine Experimental Autoimmune Encephalomyelitis. [PDF]
PLoS ONE, 2015 The cysteine cathepsins B, S, and L are functionally linked to antigen processing, and hence to autoimmune disorders such as multiple sclerosis. Stemming from several studies that demonstrate that mice can be protected from experimental autoimmune ...
Euan Ramsay Orr Allan +1 more
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THE PURIFICATION OF CATHEPSIN [PDF]
Journal of General Physiology, 1940 1. One mg. of the purified cathepsin whose preparation is described is as active as the extract of 1.3 gm. of spleen. An eightfold further purification is possible by procedures which are still being modified and so are not described in the present paper. 2.
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Expression of Cathepsins B, D and G in Infantile Hemangioma
Frontiers in Surgery, 2015 Aims: The role of the renin-angiotensin system (RAS) in the biology of infantile hemangioma (IH) represents an emerging paradigm, particularly the involvement of renin, angiotensin converting enzyme and angiotensin II.
Tinte eItinteang +6 more
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THE ESTIMATION OF CATHEPSIN WITH HEMOGLOBIN AND THE PARTIAL PURIFICATION OF CATHEPSIN [PDF]
Journal of General Physiology, 1937 An account of previous work on cathepsin may be found in the monograph of Pozzi (1935). In the hemoglobin method for the estimation of protelnase, denatured hemoglobin is digested and the digestion products not precipitable by trichloracefic acid are estimated colorimetrically.
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Frontiers in Immunology, 2022 The P2X7 receptor is a critical purinergic receptor in immune cells. Its activation was associated with cathepsin release into macrophage cytosol, suggesting its involvement in lysosomal membrane permeabilization (LMP) and leakage.
Stephanie Alexia Cristina Silva Santos +10 more
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PLoS ONE, 2015 Cathepsins are proteases involved in the ability of parasites to overcome and/or modulate host defenses so as to complete their own lifecycle. However, the mechanisms underlying this ability of cathepsins are still poorly understood.
Waleska Maldonado-Aguayo +3 more
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The role of lysosomal cysteine proteases in tumor progression
Бюллетень сибирской медицины, 2009 Cysteine cathepsins have been known for a long time to play an important role in cancer progression. Here we summarize their impact to the hallmark processes of malignant growth such as cell proliferation, apoptosis, angiogenesis, invasion and metastasis.
M. S. Korovin +2 more
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Marine Drugs, 2023 Nocuolin A (1), an oxadiazine, was isolated from the cyanobacterium Nostoc sp. Its chemical structure was elucidated using NMR and mass spectroscopic data. From this compound, two new oxadiazines, 3-[(6R)-5,6-dihydro-4,6-dipentyl-2H-1,2,3-oxadiazin-2-yl]-
Víctor Tena Pérez +7 more
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