Results 51 to 60 of about 23,676,347 (287)

Bone Mineral Density After Contemporary Treatment for Acute Lymphoblastic Leukaemia: A Matched Cross‐Sectional Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Reduced bone mineral density (BMD) has been reported in survivors of childhood and young adult acute lymphoblastic leukaemia (ALL); however, data from cohorts treated with contemporary protocols and including matched controls remain limited.
Karen Schow Jensen, Mette Tiedemann Skipper, Niels Holtum Birkebæk, Kjeld Schmiegelow, Thomas Leth Frandsen, Bente Langdahl, Rikke Beck Jensen, Asger Roer Pedersen, Christian Mølgaard, Liv Andrés‐Jensen, Birgitte Klug Albertsen   +10 more
wiley   +1 more source

Causal Mediation Analysis in Single Case Experimental Designs: Introduction to the Special Issue [PDF]

, 2022
Miocevic M, Moeyaert M, Mayer A, Montoya AK. Causal Mediation Analysis in Single Case Experimental Designs: Introduction to the Special Issue. Evaluation and the Health Professions.
Miocevic, Milica, Mayer, Axel ; https://orcid.org/, Moeyaert, Mariola, Montoya, Amanda K, Mayer, Axel, Mariola Moeyaert, Axel Mayer, Amanda K. Montoya, Milica Miočević   +8 more
core   +1 more source

Causal mediation analysis in the context of clinical research [PDF]

Annals of Translational Medicine, 2016
Clinical researches usually collected numerous intermediate variables besides treatment and outcome. These variables are often incorrectly treated as confounding factors and are thus controlled using a variety of multivariable regression models depending on the types of outcome variable.
Zhongheng, Zhang, Cheng, Zheng, Chanmin, Kim, Sven, Van Poucke, Su, Lin, Peng, Lan   +5 more
openaire   +2 more sources

Causal Mediation Analysis with Multi-dimensional and Indirectly Observed Mediators

CoRR, 2023
Causal mediation analysis (CMA) is a powerful method to dissect the total effect of a treatment into direct and mediated effects within the potential outcome framework. This is important in many scientific applications to identify the underlying mechanisms of a treatment effect.
Ziyang Jiang, Yiling Liu, Michael Hunter Klein, Ahmed Aloui, Yiman Ren, Keyu Li, Vahid Tarokh, David E. Carlson   +7 more
openaire   +3 more sources

Exercise Capacity, Physical Activity, Fatigue, and Neurocognitive Function in Adult Survivors of Childhood Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adult survivors of childhood acute lymphoblastic leukemia (ALL) are at risk of reduced exercise capacity, decreased physical activity levels, persistent fatigue, and neurocognitive deficits. The aim was to investigate exercise capacity and physical activity levels of adult survivors of childhood ALL and their associations with ...
Laura Jess, Gustaf Glavå, Simon Skau, Hans‐Georg Kuhn, Maria Bäck, Marianne Jarfelt   +5 more
wiley   +1 more source

Mediation: R Package for Causal Mediation Analysis

, 2019
In this paper, we describe the R package mediation for conducting causal mediation analysis in applied empirical research. In many scientific disciplines, the goal of researchers is not only estimating causal effects of a treatment but also understanding
Keele, Luke, Yamamoto, Teppei, Hirose, Kentaro, Imai, Kosuke, Tingley, Dustin   +4 more
core   +1 more source

Body mass index, smoking behavior, and depression mediated the effects of schizophrenia on chronic obstructive pulmonary disease: trans-ethnic Mendelian-randomization analysis

Frontiers in Psychiatry
BackgroundPrevious studies have highlighted the association between schizophrenia (SCZ) and chronic obstructive pulmonary disease (COPD), yet the causal relationship remains unestablished.MethodsUnder the genome-wide significance threshold (P<5×10–8),
Yao Ni, DaWei Zhang, DaWei Zhang, Wenlong Tang, Liming Xiang, Xiaoding Cheng, Youqian Zhang, Yanyan Feng   +7 more
doaj   +1 more source

Applied mediation analyses: a review and tutorial [PDF]

Epidemiology and Health, 2017
In recent years, mediation analysis has emerged as a powerful tool to disentangle causal pathways from an exposure/treatment to clinically relevant outcomes.
Theis Lange, Kim Wadt Hansen, Rikke Sørensen, Søren Galatius   +3 more
doaj   +1 more source

Therapeutic Apheresis in Nigeria: A Multi‐Center Summary of Abstracts From the Inaugural Nigerian Society for Apheresis Scientific Meeting

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Therapeutic apheresis (TA) is an established treatment modality for hematologic, neurologic, and immunologic disorders, yet access remains severely limited in sub‐Saharan Africa. Donor apheresis, including platelet apheresis collection from healthy donors, represents an important complementary modality supporting blood product ...
Nosa Bazuaye, Chimezie Okwuonu, Evelyn Idam, Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Zinnah Aloziem, Blossom Amamchukwu, Patience Elimia, Mkpoikanabasi Obot‐Obot, Henry Mbakwe, Praises Maduagwuna, Olatunji Akinrodoye, Chiamaka Anyanwu, Benjamin Anyanwu, Adedamola Akinsiku, Oluwatoyin A. Akinsiku, Muzamil O. Hassan, Fatiu A. Arogundade, Olalekan E. Ojo, Homayemem Weli, Jesupelumi Adenihun, Aderemi Adelaja, Ebun Bamgboye, Olalekan Olatise, Ade E. Faponle, Ayoola Odeyemi, Michael Muoka, Stephen Asaolu, Qudrat Busari, Blessing Dawudu, Michael Naiyeju, Rasheed A. Balogun   +33 more
wiley   +1 more source

Causal mediation analysis with a three‐dimensional image mediator

Statistics in Medicine
Causal mediation analysis is increasingly abundant in biology, psychology, and epidemiology studies and so forth. In particular, with the advent of the big data era, the issue of high‐dimensional mediators is becoming more prevalent. In neuroscience, with the widespread application of magnetic resonance technology in the field of brain imaging, studies
Minghao Chen, Yingchun Zhou
openaire   +3 more sources