Brain‐peripheral proteome crosstalk in Alzheimer's disease with and without diabetes mellitus
Abstract BACKGROUND Although considerable research has investigated diabetes mellitus (DM) as a risk factor for Alzheimer's disease (AD) dementia, the mechanistic understanding of the associations between peripheral and central biological processes in AD and AD within DM remains limited.
Anat Yaskolka Meir +10 more
wiley +1 more source
Corrigendum: Ganglioside GM1 promotes contact inhibition of growth by regulating the localization of epidermal growth factor receptor from glycosphingolipid‐enriched microdomain to caveolae Article DOI: 10.1111/cpr.12639 [PDF]
Dinghao Zhuo, Feng Guan
openalex +1 more source
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA), marked by amyloid beta (Aβ) accumulation in perivascular spaces (PVSs), contributes to vascular injury and inflammation in Alzheimer's disease. The mechanisms underlying CAA‐related vascular pathology remain unclear.
Vishal Singh +7 more
wiley +1 more source
The caveolae‐associated coiled‐coil protein,
Andrés Trávez +13 more
openalex +1 more source
Caveolae respond to acute oxidative stress through membrane lipid peroxidation, cytosolic release of CAVIN1, and downstream regulation of NRF2 [PDF]
Yeping Wu +9 more
openalex +1 more source
Nanobiotechnology‐Based Approaches for Targeted Glioma Therapy
Nanoparticle systems cross the blood–brain barrier to deliver drugs precisely to glioma cells. Lipid, polymeric, and magnetic carriers enable controlled release, tumor targeting, and microenvironment modulation. These nanoplatforms enhance chemotherapy, radiotherapy, and immunotherapy, improving therapeutic efficacy while reducing systemic toxicity ...
Jinwei Li +11 more
wiley +1 more source
Induction of Caveolae in the Apical Plasma Membrane of Madin-Darby Canine Kidney Cells [PDF]
Paul Verkade +3 more
openalex +1 more source
Selection of Host Plasma Membrane Lipids by HIV‐1 Gag Protein
Enrichment of sphingomyelin in the HIV‐1 envelope arises from Gag binding to PI(4,5)P2, which triggers reorganization of plasma membrane sphingomyelin/cholesterol domains through unknown mechanisms. We propose that cholesterol‐mediated interleaflet coupling between sphingomyelin and PI(4,5)P2, rather than interdigitation, underlies Gag‐induced lipid ...
Nario Tomishige +2 more
wiley +1 more source

