Impact of polyplex micelles installed with cyclic RGD peptide as ligand on gene delivery to vascular lesions [PDF]
, 2010 Gene therapy is expected to open a new strategy for the treatment of refractory vascular diseases, so the development of appropriate gene vectors for vascular lesions is needed. To realize this requirement with a non-viral approach, cyclo(RGDfK) peptide (
Hideo Kagaya +7 more
core +1 more source
Overexpression of the ABC Transporter BmrA Within Intracellular Caveolae in Escherichia coli
, 2022 Alexia Gobet +7 more
openalex +2 more sources
From Molecule to Meaning: Neuronopathic Biomarkers and Clinical Relevance in GM1
Journal of Inherited Metabolic Disease, Volume 49, Issue 1, January 2026.ABSTRACT GM1 gangliosidosis is a rare, progressively neurodegenerative lysosomal storage disorder characterized by profound central nervous system involvement and substantial clinical heterogeneity. The development of reliable biomarkers is essential for tracking disease progression, stratifying patients, and advancing clinical trial readiness. Primary
Krista Casazza +3 more
wiley +1 more source
Cholesterol Oxidation Switches the Internalization Pathway of Endothelin Receptor Type A from Caveolae to Clathrin-coated Pits in Chinese Hamster Ovary Cells [PDF]
, 2000 Yasuo Okamoto +3 more
openalex +1 more source
Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications
Small Science, Volume 6, Issue 1, January 2026.Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang +3 more
wiley +1 more source
Small Science, Volume 6, Issue 1, January 2026.This study develops core@shell nanocarriers with an exceptionally high chemotherapy drug payload, exhibiting strong cytotoxic effects. Using this adaptable nanocarrier‐synthesis platform, herein, the cellular uptake pathway and intracellular journey of the nanocarriers are elucidated with different probe‐based imaging strategies.
Dolma Choezom +11 more
wiley +1 more source
Transforming growth factor-β receptors localize to caveolae and regulate endothelial nitric oxide synthase in normal human endothelial cells [PDF]
, 2005 Eric A. Schwartz +3 more
openalex +1 more source
Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components
Small Methods, Volume 10, Issue 2, 22 January 2026.The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu +6 more
wiley +1 more source
Caveolae and caveolins role in health and disease
Кардиоваскулярная терапия и профилактика, 2008 Discovered more than 50 years ago, caveolae for a long time have remained enigmatic plasmalemmal organelles. They were described as 50-100-nm invaginations of the plasma membrane observed using electron microscopy.
R. I. Voroblev +4 more
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