Cellular uptake of nanoparticles: Involvement of caveolae?
Here we discuss some pitfalls and challenges briefly when investigating which endocytic mechanisms are involved in the cellular uptake of nanoparticles.
Tore Skotland +2 more
doaj +2 more sources
Hippo pathway regulates caveolae expression and mediates flow response via caveolae [PDF]
The Hippo pathway is a key regulator of cell survival, proliferation and tissue homeostasis. In addition, it is vital for development and regeneration.
Rausch, Valentina Jana Laura
core +1 more source
Regulation of caveolae through cholesterol-depletion dependent tubulation by PACSIN2/Syndapin II [PDF]
The membrane shaping ability of PACSIN2 via its FCH-BAR (F-BAR) domain has been shown to be essential for caveolar morphogenesis, presumably through the shaping of the caveolar neck. Caveolar membrane contains abundant levels of cholesterol. However, the
24858 +17 more
core +1 more source
Lipid accumulation controls the balance between surface connection and scission of caveolae
Caveolae are bulb-shaped invaginations of the plasma membrane (PM) that undergo scission and fusion at the cell surface and are enriched in specific lipids.
Madlen Hubert +6 more
doaj +1 more source
Introduction of caveolae structural proteins into the protozoan Toxoplasma results in the formation of heterologous caveolae but not caveolar endocytosis. [PDF]
Present on the plasma membrane of most metazoans, caveolae are specialized microdomains implicated in several endocytic and trafficking mechanisms. Caveolins and the more recently discovered cavins are the major protein components of caveolae.
Bao Lige +5 more
doaj +1 more source
Theoretical model for the formation of caveolae and similar membrane invaginations [PDF]
We study a physical model for the formation of bud-like invaginations on fluid lipid membranes under tension, and apply this model to caveolae formation.
Turner, Matthew S. +2 more
core +1 more source
Actin-Cytoskeleton Drives Caveolae Signaling to Mitochondria during Postconditioning
Caveolae-associated signaling toward mitochondria contributes to the cardioprotective mechanisms against ischemia-reperfusion (I/R) injury induced by ischemic postconditioning.
Francisco Correa +10 more
doaj +1 more source
Cell Biology of Caveolae and Its Implication for Clinical Medicine [PDF]
2000-05Caveolae are small invaginations of the plasma membrane found in many cell types, and caveolins are integral membrane proteins that form the framework of caveolae.
FUJIMOTO, TOYOSHI
core +1 more source
Energy and Dynamics of Caveolae Trafficking
Caveolae are 70–100 nm diameter plasma membrane invaginations found in abundance in adipocytes, endothelial cells, myocytes, and fibroblasts. Their bulb-shaped membrane domain is characterized and formed by specific lipid binding proteins including ...
Claudia Matthaeus, Justin W. Taraska
doaj +1 more source
Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders.
Maider Varela-Guruceaga +7 more
doaj +1 more source

