Results 31 to 40 of about 44,676 (226)

Manipulation of lipid rafts in neuronal cells [PDF]

open access: yes, 2010
Lipid rafts are specialized plasma membrane micro-domains highly enriched in cholesterol, sphingolipids and glycosylphosphatidylinositol (GPI) anchored proteins.
Eckert, Gunter P.
core   +1 more source

Analysis of CD44-containing lipid rafts: Recruitment of annexin II and stabilization by the actin cytoskeleton [PDF]

open access: yes, 1999
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells.
Oliferenko, S.   +8 more
core   +1 more source

Caveolae structure and function [PDF]

open access: yesJournal of Cellular and Molecular Medicine, 2008
Studies on the structure and function of caveolae have revealed how this versatile subcellular organelle can influence numerous signalling pathways. This brief review will discuss a few of the key features of caveolae as it relates to signalling and disease processes.
Thomas, Candice M, Smart, Eric J
openaire   +2 more sources

Caveolae as Potential Hijackable Gates in Cell Communication

open access: yesFrontiers in Cell and Developmental Biology, 2020
Caveolae are membrane microdomains described in many cell types involved in endocytocis, transcytosis, cell signaling, mechanotransduction, and aging. They are found at the interface with the extracellular environment and are structured by caveolin and ...
Maria Dudãu   +10 more
doaj   +1 more source

Enhancing anticancer cytotoxicity through bimodal drug delivery from ultrasmall Zr MOF nanoparticles [PDF]

open access: yes, 2018
Dual delivery of dichloroacetate and 5-fluorouracil from Zr MOFs into cancer cells is found to enhance in vitro cytotoxicity. Tuning particle size and, more significantly, surface chemistry, further improves cytotoxicity by promoting caveolae-mediated ...
Abánades Lázaro, Isabel   +2 more
core   +1 more source

Selective Cholesterol Dynamics between Lipoproteins and Caveolae/Lipid Rafts [PDF]

open access: yes, 2007
Although low-density lipoprotein (LDL) receptor-mediated cholesterol uptake through clathrin-coated pits is now well understood, the molecular details and organizing principles for selective cholesterol uptake/efflux (reverse cholesterol transport, RCT ...
Atshaves, Barbara P.   +9 more
core   +2 more sources

Caveolae at a glance [PDF]

open access: yesJournal of Cell Science, 2010
The plasma membrane is more than a simple delimitation of the boundary of the cell but is a dynamic multi-domain membrane system participating in numerous cellular processes. In many different cell types, the plasma membrane is heavily decorated with small pits of 60–80 nm in diameter ...
Bastiani, M, Parton, RG
openaire   +3 more sources

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

open access: yes, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
A Bist   +103 more
core   +7 more sources

Cellular uptake of nanoparticles: Involvement of caveolae?

open access: yesPrecision Nanomedicine, 2021
Here we discuss some pitfalls and challenges briefly when investigating which endocytic mechanisms are involved in the cellular uptake of nanoparticles.
Tore Skotland   +2 more
doaj   +1 more source

Plasma from Volunteers Breathing Helium Reduces Hypoxia-Induced Cell Damage in Human Endothelial Cells-Mechanisms of Remote Protection Against Hypoxia by Helium. [PDF]

open access: yes, 2019
PurposeRemote ischemic preconditioning protects peripheral organs against prolonged ischemia/reperfusion injury via circulating protective factors. Preconditioning with helium protected healthy volunteers against postischemic endothelial dysfunction.
Augustijn, Quinten JJ   +7 more
core   +1 more source

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