Results 41 to 50 of about 44,676 (226)

Glycolipid‐Enriched Caveolae and Caveolae‐Like Domains in the Nervous System [PDF]

Journal of Neurochemistry, 1999
Abstract: Recent years have been characterized by a booming interest in research on caveolae and caveolae‐like membrane domains. The interest in this subject grew further, when their involvement in fundamental membrane‐associated events, such as signal transmission and lipid/protein sorting, was postulated.
MASSERINI, MASSIMO ERNESTO, PALESTINI, PAOLA NOVERINA ADA, PITTO, MARINA   +2 more
openaire   +2 more sources

Super-resolution analysis of PACSIN2 and EHD2 at caveolae.

PLoS ONE, 2022
Caveolae are plasma membrane invaginations that play important roles in both endocytosis and membrane tension buffering. Typical caveolae have invaginated structures with a high-density caveolin assembly.
Tamako Nishimura, Shiro Suetsugu
doaj   +1 more source

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls [PDF]

, 2010
Nonviral gene complexes can enter mammalian cells through different endocytic pathways. For efficient optimization of the gene carrier it is important to profile its cellular uptake, because this largely determines its intracellular processing and ...
Dries Vercauteren, Roosmarijn E Vandenbroucke, Arwyn T Jones, Joanna Rejman, Joseph Demeester, Stefaan C De Smedt, Niek N Sanders, Kevin Braeckmans, Wattiaux, Conner, Jones, Grimmer, Rejman, Widera, Maxfield, Mayor, Simons, Parton, Pelkmans, Torgersen, Puri, Singh, Marks, Zuhorn, Glebov, Medina-Kauwe, Khalil, Elouahabi, Midoux, von Gersdorff, Douglas, Wong, Gabrielson, Banks, Ivanov, Wang, Larkin, Rodal, Parton, Nabi, Gonçalves, Nichols, Hinrichsen, Huang, Vanden Broeck, Benmerah, Payne, Damke, Liu, Lamaze, Rejman, Mano, Weyermann, Subtil, Huth, Davis, Yuwen, Sonnichsen   +57 more
core   +3 more sources

Genetically Encoded Biosensors Reveal PKA Hyperphosphorylation on the Myofilaments in Rabbit Heart Failure [PDF]

, 2016
RATIONALE: In heart failure, myofilament proteins display abnormal phosphorylation, which contributes to contractile dysfunction. The mechanisms underlying the dysregulation of protein phosphorylation on myofilaments is not clear.
Barbagallo, Federica, Bers, Donald, Bossuyt, Julie, Ferrier, William, Fu, Qin, Ginsburg, Kenneth S., Isidori, Andrea, Li, Minghui, Naro, Fabio, Patel, Hemal H., Reddy, Gopireddy R., Shi, Qian, Wang, Qingtong, West, Toni, Xiang, Yang K., Xu, Bing   +15 more
core   +1 more source

The Role of Glycocalyx and Caveolae in Vascular Homeostasis and Diseases

Frontiers in Physiology, 2021
This review highlights recent findings about the role that endothelial glycocalyx and caveolae play in vascular homeostasis. We describe the structure, synthesis, and function of glycocalyx and caveolae in vascular cells under physiological and ...
Simone Regina Potje, Tiago Dal-Cin Paula, Michele Paulo, Lusiane Maria Bendhack   +3 more
doaj   +1 more source

Caveolin-1 expression and cavin stability regulate caveolae dynamics in adipocyte lipid store fluctuation [PDF]

, 2014
Adipocytes specialized in the storage of energy as fat are among the most caveolae-enriched cell types. Loss of caveolae produces lipodystrophic diabetes in humans, which cannot be reversed by endothelial rescue of caveolin expression in mice, indicating
C. Prado, E. Ravussin, F. Lasnier, G. Mabilleau, I. Dugail, J.D. Covington, N. Briand, S. Le Lay, X. Le Liepvre   +8 more
core   +4 more sources

Plasma membrane remodeling determines adipocyte expansion and mechanical adaptability

Nature Communications
Adipocytes expand massively to accommodate excess energy stores and protect the organism from lipotoxicity. Adipose tissue expandability is at the center of disorders such as obesity and lipodystrophy; however, little is known about the relevance of ...
María C. M. Aboy-Pardal, Marta C. Guadamillas, Carlos R. Guerrero, Mauro Català-Montoro, Mónica Toledano-Donado, Sara Terrés-Domínguez, Dácil M. Pavón, Víctor Jiménez-Jiménez, Daniel Jimenez-Carretero, Moreno Zamai, Cintia Folgueira, Ana Cerezo, Fidel-Nicolás Lolo, Rubén Nogueiras, Guadalupe Sabio, Miguel Sánchez-Álvarez, Asier Echarri, Ricardo Garcia, Miguel A. Del Pozo   +18 more
doaj   +1 more source

Interactions between proteins bound to biomembranes

, 2003
We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that apply forces to
A. Albersdorfer, A. Gilbert, A. Schlegel, A. Schlegel, B. Lorz, C. Hiergeist, C.E. Morris, D. Stamou, E. Evans, F.M. Brodsky, H. Park, H. Park, J.B. Fournier, K. Olbrich, K.G. Rothberg, L. Leger, M. Breidenich, M. Daoud, M. Goulian, M. Goulian, M. Goulian, M. Sargiacomo, M. Seul, M.P. Lisanti, M.P. Sheetz, R. Bruinsma, R. Golestanian, R. Lipowsky, R.J. Mashl, R.P. Sear, R.P. Sear, S. Leibler, S. Leibler, S. Monier, T. Bickel, U. Seifert, W. Hackl, W. Rawicz, W.M. Gelbart, Y.W. Kim   +39 more
core   +1 more source

Canine respiratory coronavirus employs caveolin-1-mediated pathway for internalization to HRT-18G cells [PDF]

, 2018
Canine respiratory coronavirus (CRCoV), identified in 2003, is a member of the Coronaviridae family. The virus is a betacoronavirus and a close relative of human coronavirus OC43 and bovine coronavirus.
A Milewska, A Pratelli, A Quan, Aleksandra Milewska, AM Zaki, Artur Szczepanski, B Hernaez, B Jancekova, BA Mainou, BJ Dille, C Burkard, C Kooi, C Liu, C Liu, D Dutta, DM Blau, E Dietzel, E Girard, E Hamme Van, EJ Bowman, F Samson, G Preta, GA Wudiri, GM Li, GR Ares, H Imhoff, H Lin, H Wang, IC Huang, IM Mackay, J Li, J Schindelin, J Somsel Rodman, JA Mitchell, JK Millet, JL Wang, JP Lim, JR Henley, Judy A. Mitchell, K Erles, K Erles, K Owczarek, K Shirato, K Shirato, Katarzyna Owczarek, Krzysztof Pyrc, KS Choi, L Kleist von, L Pelkmans, LH Wang, LJ Reed, M Marsh, MG Hemida, MJ Geisow, MJ Vincent, O Achour, O Heikkila, P Duckert, P Eifart, P Oh, Q Xu, R Nomura, S Bertram, S Bolte, S Gierer, S Matsuyama, SL Priestnall, TA Hill, VC Chu, X Ren, Y Inoue, Y Phonphok, Z Qian, Z Qinfen, Zbigniew Baster, Zenon Rajfur   +75 more
core   +8 more sources

Nanoplastics: From tissue accumulation to cell translocation into Mytilus galloprovincialis hemocytes. resilience of immune cells exposed to nanoplastics and nanoplastics plus Vibrio splendidus combination [PDF]

, 2020
Plastic litter is an issue of global concern. In this work Mytilus galloprovincialis was used to study the distribution and effects of polystyrene nanoplastics (PS NPs) of different sizes (50 nm, 100 nm and 1 mu m) on immune cells.
Figueras, A., Novoa, B., Romero, A., Saco, A., Sendra, M., Yeste Sigüenza, María del Pilar   +5 more
core   +1 more source