Results 121 to 130 of about 60,250 (276)

Caveolin-1 opens endothelial cell junctions by targeting catenins [PDF]

open access: yes, 2017
Aims A fundamental phenomenon in inflammation is the loss of endothelial barrier function, in which the opening of endothelial cell junctions plays a central role.
Afanasieva, Tatiana   +10 more
core  

Caveolin-1 protects B6129 mice against Helicobacter pylori gastritis. [PDF]

open access: yes, 2013
Caveolin-1 (Cav1) is a scaffold protein and pathogen receptor in the mucosa of the gastrointestinal tract. Chronic infection of gastric epithelial cells by Helicobacter pylori (H. pylori) is a major risk factor for human gastric cancer (GC) where Cav1 is
A Bist   +103 more
core   +4 more sources

Nanoplastics Impair GnRH Neuron Migration and Neuroendocrine Function: Emerging Players in the Pathogenesis of Reproductive Disorders

open access: yesSmall, EarlyView.
Little is known about the effects of polystyrene nanoplastics (PS‐NPs) on gonadotropin releasing hormone (GnRH) neurons, which control puberty onset and fertility. By applying tailored in vitro GnRH neuron models, this article shows how PS‐NPs are internalized and impact hormone secretion and cell migration, through gene expression changes. Ultimately,
Federica Amoruso   +14 more
wiley   +1 more source

Expression and clinical significance of Caveolin-1 in prostate Cancer after transurethral surgery

open access: yesBMC Urology, 2018
Background Prostate cancer is a common malignancy of the male genitourinary system that occurs worldwide. The current research aims to investigate caveolin-1 expression in prostate cancer tissue and its relationship with pathological grade, clinical ...
Xiaoming Wang, Zhigui Liu, Zhanbin Yang
doaj   +1 more source

Synergistic drug combinations from electronic health records and gene expression. [PDF]

open access: yes, 2016
ObjectiveUsing electronic health records (EHRs) and biomolecular data, we sought to discover drug pairs with synergistic repurposing potential. EHRs provide real-world treatment and outcome patterns, while complementary biomolecular data, including ...
Chen, William   +19 more
core   +2 more sources

Mechanism of Ammonia‐Induced Brain Damage in Chinese Striped‐Necked Turtle (Mauremys sinensis)

open access: yesIntegrative Zoology, EarlyView.
High levels of ammonia disrupt the integrity of the brain barrier in Mauremys sinensis, leading to tissue edema. This, in turn, triggers a series of cascade reactions, including disturbances in neurotransmitter levels, particularly glutamate, which might further exacerbate the neurotoxic effects.
Yunjuan Xiao   +6 more
wiley   +1 more source

Supplementary Table 1 from Caveolin-1 Reduces Osteosarcoma Metastases by Inhibiting c-Src Activity and Met Signaling

open access: gold, 2023
Lara Cantiani   +11 more
openalex   +1 more source

Oral Protein Therapy for the Future - Transport of Glycolipid-Modified Proteins: Vision or Fiction? [PDF]

open access: yes, 2010
The reliable and early diagnosis of common complex multifactorial diseases depends on the individual determination of all (or as many as possible) polymorphisms of each susceptibility gene together with amount and type of the corresponding gene products ...
Mueller, Guenter
core   +1 more source

The Oxytocin Receptor in Spermatozoa May Originate From Both Spermatogenesis and Epididymal Maturation, and Regulates Capacitation

open access: yesAndrology, EarlyView.
Abstract Background The oxytocin receptor (OR) is a G‐protein‐coupled receptor recently identified in human spermatozoa, whose origin and role in sperm physiology remain unknown. Objectives In this study, using the pig as a model, we examine the presence of the OR in ejaculated spermatozoa through immunofluorescence and immunoblotting, and investigate ...
Jesús Martínez‐Hernández   +9 more
wiley   +1 more source

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