Supplementary Figure 2 from Functional Interaction of Tumor Suppressor DLC1 and Caveolin-1 in Cancer Cells [PDF]
, 2023 Xiaoli Du +8 more
openalex +1 more source
Caveolin-1 Associated Adenovirus Entry into Human Corneal Cells [PDF]
, 2014 The cellular entry of viruses represents a critical area of study, not only for viral tropism, but also because viral entry dictates the nature of the immune response elicited upon infection.
Chintakuntlawar, Ashish V. +7 more
core +1 more source
Clostridium perfringens epsilon toxin induces blood brain barrier permeability via caveolae-dependent transcytosis and requires expression of MAL. [PDF]
, 2019 Clostridium perfringens epsilon toxin (ETX) is responsible for causing the economically devastating disease, enterotoxaemia, in livestock. It is well accepted that ETX causes blood brain barrier (BBB) permeability, however the mechanisms involved in this
Dobrow, Sebastian +7 more
core +1 more source
Caveolin-1, TGF-β receptor internalization, and the pathogenesis of systemic sclerosis [PDF]
, 2008 PURPOSE OF REVIEW: To review the scientific literature supporting the participation of caveolin-1 in the pathogenesis of tissue fibrosis and the notion that modulation of the caveolin-1 pathway may represent a novel treatment for systemic sclerosis and ...
Del Galdo, Francesco +2 more
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A New N-terminal Recognition Domain in Caveolin-1 Interacts with Sterol Carrier Protein-2 (SCP-2) [PDF]
, 2007 Although plasma membrane domains, such as caveolae, provide an organizing principle for signaling pathways and cholesterol homeostasis in the cell, relatively little is known regarding specific mechanisms, whereby intracellular lipid-binding proteins are
Ball, Judith M. +7 more
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Allosteric modulation of beta1 integrin function induces lung repair in animal model of emphysema. [PDF]
, 2007 Emphysema is a progressive lung disease characterised by loss of lung parenchyma with associated functional changes including decreased tissue elastance. Here we report beta1 integrin is a novel target for tissue repair and regeneration in emphysema.
Chris J. Armit +6 more
core +1 more source
Cell Propagation of Cholera Toxin CTA ADP-Ribosylating Factor by Exosome Mediated Transfer [PDF]
, 2018 In this study, we report how the cholera toxin (CT) A subunit (CTA), the enzyme moiety responsible for signaling alteration in host cells, enters the exosomal pathway, secretes extracellularly, transmits itself to a cell population.
Boussadia, Zaira +11 more
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SnapShot: Caveolae, Caveolins, and Cavins
Cell, 2013 Caveolae, submicroscopic bulb-shaped plasma membrane pits, are an abundant feature of many mammalian cells (Parton and del Pozo, 2013). Caveolae and the major proteins of caveolae, caveolins (Rothberg et al., 1992), and cavins (Hill et al., 2008), are linked to a number of human diseases such as muscular dystrophy, cardiomyopathy, and lipodys -trophy ...
Ariotti, Nicholas, Parton Robert G.
openaire +3 more sources
HDL-mediated cholesterol uptake and targeting to lipid droplets in adipocytes
Journal of Lipid Research, 2003 Adipocytes express high levels of the HDL scavenger receptor class B type I in a differentiation-dependent manner. We thus have analyzed the routes of HDL cholesterol trafficking at different phases of adipocyte differentiation in the 3T3-L1 cell line ...
Georges Dagher +4 more
doaj +1 more source
Atypical protein kinase C (PKCzeta/lambda) is a convergent downstream target of the insulin-stimulated phosphatidylinositol 3-kinase and TC10 signaling pathways. [PDF]
, 2004 Insulin stimulation of adipocytes resulted in the recruitment of atypical PKC (PKCzeta/lambda) to plasma membrane lipid raft microdomains. This redistribution of PKCzeta/lambda was prevented by Clostridium difficile toxin B and by cholesterol depletion ...
Hwang, Joseph B +4 more
core +1 more source