Results 141 to 150 of about 35,385 (262)

Recent Progress in Gene Delivery Systems Based on Gemini‐Surfactant

open access: yesMedComm – Future Medicine, Volume 4, Issue 3, September 2025.
Gene delivery is a key area in biomedicine, where nucleic acids are delivered into cells to treat diseases by modulating genes. The low micelle concentration, effective nucleic acid complexation, and low immunogenicity make Gemini surfactants promising gene delivery vectors.
Peng Qian   +5 more
wiley   +1 more source

Heterogeneity of detergent-insoluble membranes from human intestinal epithelia containing caveolin-1 and ganglioside GM1

open access: bronze, 2000
Kamran Badizadegan   +5 more
openalex   +1 more source

Elevated Expression of Caveolin-1 in Adenocarcinoma of the Colon [PDF]

open access: bronze, 2001
Samson W. Fine   +3 more
openalex   +1 more source

Annexin A1‐Targeted d‐Peptide‐Monomethyl Auristatin E Conjugate Enhanced Antitumor Effect of Monomethyl Auristatin E for Chemotherapy of Prostate Cancer

open access: yesThe Prostate, Volume 85, Issue 13, Page 1208-1221, September 15, 2025.
ABSTRACT Background N‐terminus 15 amino acid (MC16) of Annexin A1 (ANXA1) is an effective therapeutic target for tumors and tumor vasculature as it specifically localizes to the cell surface of tumor cells and tumor vascular endothelial cells. We identified the d‐type peptide (hpnevrs, dhp7) by mirror‐image phage display targeting l‐type MC16 and ...
Kai Ozaki   +8 more
wiley   +1 more source

Milk‐Derived Extracellular Vesicles and microRNAs: Potential Modulators of Intestinal Homeostasis

open access: yesThe FASEB Journal, Volume 39, Issue 16, 31 August 2025.
Upon ingestion, milk extracellular vesicles (EVs) carrying bioactive cargo like microRNAs and proteins may survive digestion and interact with intestinal epithelial cells via surface signaling or be internalized by intestinal epithelial cells to which they deliver their bioactive cargo.
Zeinab Husseini, Caroline Gilbert
wiley   +1 more source

Temporal effects of 17β-estradiol on caveolin-1 mRNA and protein in bovine aortic endothelial cells [PDF]

open access: bronze, 2001
Muthuvel Jayachandran   +4 more
openalex   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

open access: yesFEBS Open Bio, Volume 15, Issue 8, Page 1350-1364, August 2025.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal   +2 more
wiley   +1 more source

Caveolin‐1 negatively regulates SR‐BI mediated selective uptake of high‐density lipoprotein‐derived cholesteryl ester [PDF]

open access: bronze, 2001
Sergey V. Matveev   +3 more
openalex   +1 more source

Time‐Controlled Dual Targeting to Program Systemic and Intercellular Transfer of Therapeutic Effects

open access: yesAdvanced Functional Materials, Volume 35, Issue 31, August 1, 2025.
Aspirin‐liposomes loaded onto monocytes enable inflammation‐triggered targeting and efficient hand‐over of aspirin to inflamed cells. Monocytes uptake a significant portion of aspirin‐liposomes, prolonging therapeutic action. This approach enhances anti‐inflammatory effects through intercellular transfer, demonstrating a translational strategy for ...
Seung Eun Yu   +6 more
wiley   +1 more source

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