Results 71 to 80 of about 6,074 (242)
Advanced Science, EarlyView.This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo +9 more
wiley +1 more source
Caveolin-1, caveolae, and glioblastoma [PDF]
Neuro-Oncology, 2012 Glioblastoma multiforme (GBM) is the most common malignant brain tumor and is characterized by high invasiveness, poor prognosis, and limited therapeutic options. Biochemical and morphological experiments have shown the presence of caveolae in glioblastoma cells. Caveolae are flask-shaped plasma membrane subdomains that play trafficking, mechanosensing,
Parat, Marie-Odile, Riggins, Gregory J.
openaire +3 more sources
Introduction of caveolae structural proteins into the protozoan Toxoplasma results in the formation of heterologous caveolae but not caveolar endocytosis. [PDF]
PLoS ONE, 2012 Present on the plasma membrane of most metazoans, caveolae are specialized microdomains implicated in several endocytic and trafficking mechanisms. Caveolins and the more recently discovered cavins are the major protein components of caveolae.
Bao Lige +5 more
doaj +1 more source
Characterization of Zika virus endocytic pathways in human glioblastoma cells [PDF]
, 2020 Zika virus (ZIKV) infections can cause microcephaly and neurological disorders. However, the early infection events of ZIKV in neural cells remain to be characterized. Here, by using a combination of pharmacological and molecular approaches and the human
Du, T +11 more
core +1 more source
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
PLoS ONE, 2017 Caveolae are membrane invaginations present at high densities in muscle and fat. Recent work has demonstrated that myocardin family coactivators (MYOCD, MKL1), which are important for contractile differentiation and cell motility, increase caveolin (CAV1,
Baoyi Zhu +7 more
doaj +1 more source
Sudden cardiac death: focus on the genetics of channelopathies and cardiomyopathies
Journal of Biomedical Science, 2017 Sudden cardiac death (SCD) describes a natural and unexpected death from cardiac causes occurring within a short period of time (generally within 1 h of symptom onset) in the absence of any other potentially lethal condition.
Simona Magi +4 more
doaj +1 more source
Membranes, 2021 Caveolins are critical for the formation of caveolae, which are small invaginations of the plasma membrane involved in a variety of biological processes.
Hae-Jun Park +8 more
doaj +1 more source
Interactions between proteins bound to biomembranes
, 2003 We study a physical model for the interaction between general inclusions bound to fluid membranes that possess finite tension, as well as the usual bending rigidity. We are motivated by an interest in proteins bound to cell membranes that apply forces to
A. Albersdorfer +39 more
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Membrane shape as a reporter for applied forces [PDF]
, 2008 Recent advances have enabled 3-dimensional reconstructions of biological structures in vivo, ranging in size and complexity from single proteins to multicellular structures. In particular, tomography and confocal microscopy have been exploited to capture
Antonny +30 more
core +2 more sources