Results 81 to 90 of about 3,741 (219)
CAVEOLINS AND CAVINS IN MUSCLE-DERIVED TUMOURS
, 2012 Rhabdomyosarcomas (RMS) are muscle-derived tumours with a significant incidence in children. RMS cells exhibit a widespread pattern of muscle-specific markers, the detection of which may be useful for discriminating the tumour grading in order to ...
ZANOLA, Alessandra +6 more
core +1 more source
PLoS ONE, 2017 Anthracyclines are chemotherapeutic drugs known to induce heart failure in a dose-dependent manner. Mechanisms involved in anthracycline cardiotoxicity are an area of relevant investigation.
Yasuhiro Ichikawa +8 more
doaj +1 more source
The Secret (Mitotic) Life of Clathrin. [PDF]
TrafficA perspective on the function of clathrin at the mitotic spindle during cell division. ABSTRACT The discovery of clathrin was a foundational event in membrane traffic research. Its identification as the major protein component of the coat that surrounds endocytic vesicles kickstarted the biochemical and molecular characterization of endocytosis. During
Royle SJ.
europepmc +2 more sources
Smart Molecules, EarlyView.The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang +8 more
wiley +1 more source
CRITICAL NEUROPROTECTIVE ROLE OF CAVEOLINS IN THE RETINAL GANGLION CELLS
, 2012 CRITICAL NEUROPROTECTIVE ROLE OF CAVEOLINS IN THE RETINAL GANGLION ...
Vivek Gupta (13420509) +3 more
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World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.ABSTRACT Hypopharyngeal squamous cell carcinoma (HSCC) is an aggressive subtype of head and neck squamous cell carcinoma with insidious onset, early metastasis, and dismal prognosis. Conventional multimodal therapy achieves limited survival benefit, highlighting an urgent need for refined precision strategies.
Ce Li +12 more
wiley +1 more source
A novel myopathy with autophagic vacuoles associated with biallelic variants in CLN8
Brain Pathology, EarlyView.We describe a novel adult‐onset myopathy with autophagic vacuoles and characteristic features of ceroid lipofuscinosis associated with biallelic CLN8 variants, seizures, and muscle weakness. Autophagosomal/lysosomal deposition of curvilinear, autofluorescent material containing the mitochondrial adenosine triphosphate (ATP) synthase membrane subunit c ...
Ulrika Lindgren +5 more
wiley +1 more source
Regulation of caveolin and caveolae by cholesterol in MDCK cells
Journal of Lipid Research, 1998 We have examined the expression of caveolin in MDCK cells under conditions that vary cellular cholesterol concentration. Caveolin mRNA levels dropped to one-sixth of control levels after treatment with simvastatin, an inhibitor of cholesterol synthesis ...
Deborah Hailstones +3 more
doaj +1 more source
Identification and Characterization of Caveolins in Mouse Macrophages [PDF]
, 2013 Peter Gargalovic, Identification and Characterization of Caveolins in Mouse Macrophages. Doctor of Philosophy (Biochemistry and Molecular Biology), December 2002, 206 pp., 3 tables, 41 illustrations, references, 296 titles.
Gargalovic, Peter
core
Age-related influence of hypothyroidism on caveolins and nitric oxide modulation [PDF]
, 2014 Introduction: Hypothyroidism and age impact on cardiac and renal nitricoxide (NO) production. Caveolins, which are negativemodulators of NO synthase (NOS) activity, are affected byboth factors.
Balaszczuk, Ana María +11 more
core +1 more source