Results 31 to 40 of about 24,428,123 (145)

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

open access: yeseLife, 2014
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae.
Yann Gambin   +18 more
doaj   +1 more source

Cavin 2 and cavin 3 form distinct subcomplexes with cavin 1 and caveolin 1.

open access: yes, 2013
(A) Gradient fractions (10–40% sucrose) of non-cross-linked and detergent solubilised (1% Triton X-100) HeLa cell extracts were analysed by Western blotting.
Gillian Howard (450875)   +7 more
core   +1 more source

Cavin-1 and Cavin-3, but not Cavin-2 and Cavin-4 negatively regulate CLIC endocytosis.

open access: yes, 2014
(A) CAV1−/− MEFs were transiently transfected with pIRES-GFP, pIRES-Cavin-1, pIRES-Cavin-2, pIRES-Cavin-3, and pIRES-Cavin-4 respectively and internalization assay was performed with anti-CD44 mAb and Tfn-647 for 2 min at 37°C.
Katharina Gaus (47632)   +10 more
core   +1 more source

Description of large, well‐preserved Enchodus specimens from the Bearpaw Formation of Alberta, Canada

open access: yesThe Anatomical Record, EarlyView.
Abstract Fishes of the genus Enchodus were abundant and cosmopolitan in the Late Cretaceous, but are primarily known from isolated remains in Canada. Four well‐preserved fish skulls were recovered in recent years from ammolite mines sampling the Bearpaw Formation of Southern Alberta, and are here referred to Enchodus petrosus Cope, 1874.
Luke E. Nelson   +2 more
wiley   +1 more source

Updated COVID‐19 Vaccines and Health Outcomes in Patients With Autoimmune Rheumatic Conditions

open access: yesArthritis &Rheumatology, EarlyView.
Objective We aimed to assess the association between COVID‐19 vaccination status and COVID‐19‐related hospital admissions, need for mechanical ventilation or extracorporeal membrane oxygenation (ECMO), and death in people with autoimmune rheumatic conditions. Methods We conducted a retrospective cohort study using National Clinical Cohort Collaborative
Lesley E. Jackson   +127 more
wiley   +1 more source

Pathophysiological Role of Caveolae in Hypertension

open access: yesFrontiers in Medicine, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1–4, EHD2, pacsin2, and dynamin 2.
Xiaoming Lian   +5 more
doaj   +1 more source

Extracellular Vesicles‐Based Biological Macromolecule Delivery Systems: Biogenesis, Characterization, and Emerging Clinical Applications

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale membrane‐bound structures that play a pivotal role in intercellular communication by transporting bioactive molecules, including proteins, lipids, nucleic acids, and organelles, between cells. Originating from the endosomal pathway, EVs reflect the physiological and pathological status of their parent
Emine İncilay Torunoğlu   +3 more
wiley   +1 more source

Interview with Amanda Cavin - OH 713

open access: yes, 2021
This interview was conducted by Baylee Hughes with Amanda Cavin as part of the “Being LGBTQIA+ at Winthrop” Oral History Project spearheaded by Baylee Hughes.
Cavin, Amanda
core  

Myocardin Family Members Drive Formation of Caveolae.

open access: yesPLoS ONE, 2015
Caveolae are membrane organelles that play roles in glucose and lipid metabolism and in vascular function. Formation of caveolae requires caveolins and cavins.
Katarzyna K Krawczyk   +11 more
doaj   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

open access: yesBMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang   +13 more
wiley   +1 more source

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