Results 21 to 30 of about 2,002 (125)

Gene and Protein Accumulation Changes Evoked in Porcine Aorta in Response to Feeding with Two Various Fructan Sources

Animals, 2022
In this study, two different ITFs sources were incorporated into a cereal-based diet to evaluate possible aortic protein and gene changes in nursery pigs.
Marta Marynowska, Agnieszka Herosimczyk, Adam Lepczyński, Marcin Barszcz, Adrianna Konopka, Aleksandra Dunisławska, Małgorzata Ożgo   +6 more
doaj   +1 more source

Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development

Frontiers in Physiology, 2020
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders.
Maider Varela-Guruceaga, Elise Belaidi, Lucie Lebeau, Ella Aka, Ramaroson Andriantsitohaina, Sophie Giorgetti-Peraldi, Claire Arnaud, Soazig Le Lay   +7 more
doaj   +1 more source

Galectin-3 Overrides PTRF/Cavin-1 Reduction of PC3 Prostate Cancer Cell Migration. [PDF]

PLoS ONE, 2015
Expression of Caveolin-1 (Cav1), a key component of cell surface caveolae, is elevated in prostate cancer (PCa) and associated with PCa metastasis and a poor prognosis for PCa patients.
Fanrui Meng, Bharat Joshi, Ivan Robert Nabi   +2 more
doaj   +1 more source

Cavin-3 knockout mice show that cavin-3 is not essential for caveolae formation, for maintenance of body composition, or for glucose tolerance.

PLoS ONE, 2014
The cavins are a family of proteins associated with caveolae, cavin-1, -2 and -3 being widely expressed while cavin-4 is restricted to striated muscle.
Libin Liu, Carsten G Hansen, Brian J Honeyman, Benjamin J Nichols, Paul F Pilch   +4 more
doaj   +1 more source

Molecular composition and ultrastructure of the caveolar coat complex.

PLoS Biology, 2013
Caveolae are an abundant feature of the plasma membrane of many mammalian cell types, and have key roles in mechano-transduction, metabolic regulation, and vascular permeability.
Alexander Ludwig, Gillian Howard, Carolina Mendoza-Topaz, Thomas Deerinck, Mason Mackey, Sara Sandin, Mark H Ellisman, Benjamin J Nichols   +7 more
doaj   +1 more source

Inhibition of Cavin3 Degradation by the Human Parainfluenza Virus Type 2 V Protein Is Important for Efficient Viral Growth

Frontiers in Microbiology, 2020
Cavin proteins have important roles in the formation of caveolae in lipid raft microdomains. Pulse-chase experiments of cells infected with human parainfluenza virus type 2 (hPIV-2) showed decreased proteasomal degradation of Cavin3.
Keisuke Ohta, Yusuke Matsumoto, Machiko Nishio   +2 more
doaj   +1 more source

S138 Blood outgrowth endothelial cells isolated from patients with pulmonary arterial hypertension possess less caveolae and reduced cavin-2 expression [PDF]

Thorax, 2013
Pulmonary arterial hypertension (PAH) is a progressive disease characterised by a marked elevation in pulmonary arterial pressure due to increased muscularisation and obliteration of small pulmonary arteries. The majority of heritable PAH cases are due to mutations in members of the transforming growth factor-β (TGFβ) receptor signalling pathway ...
BJ Dunmore, G Howard, A Crosby, BJ Nichols, NW Morrell   +4 more
openaire   +1 more source

Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis.

PLoS Biology, 2014
Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear.
Natasha Chaudhary, Guillermo A Gomez, Mark T Howes, Harriet P Lo, Kerrie-Ann McMahon, James A Rae, Nicole L Schieber, Michelle M Hill, Katharina Gaus, Alpha S Yap, Robert G Parton   +10 more
doaj   +1 more source

Listeria monocytogenes Exploits Host Caveolin for Cell-to-Cell Spreading

mBio, 2020
Listeria monocytogenes moves from one cell to another using actin-rich membrane protrusions that propel the bacterium toward neighboring cells. Despite cholesterol being required for this transfer process, the precise host internalization mechanism ...
Aaron S. Dhanda, Connie Yu, Katarina T. Lulic, A. Wayne Vogl, Valentina Rausch, Diana Yang, Benjamin J. Nichols, Sung Hyun Kim, Simona Polo, Carsten G. Hansen, Julian A. Guttman   +10 more
doaj   +1 more source

Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae

eLife, 2014
In mammalian cells three closely related cavin proteins cooperate with the scaffolding protein caveolin to form membrane invaginations known as caveolae.
Yann Gambin, Nicholas Ariotti, Kerrie-Ann McMahon, Michele Bastiani, Emma Sierecki, Oleksiy Kovtun, Mark E Polinkovsky, Astrid Magenau, WooRam Jung, Satomi Okano, Yong Zhou, Natalya Leneva, Sergey Mureev, Wayne Johnston, Katharina Gaus, John F Hancock, Brett M Collins, Kirill Alexandrov, Robert G Parton   +18 more
doaj   +1 more source