Results 21 to 30 of about 24,428,123 (145)

PTRF/Cavin-1 Deficiency Causes Cardiac Dysfunction Accompanied by Cardiomyocyte Hypertrophy and Cardiac Fibrosis. [PDF]

PLoS ONE, 2016
Mutations in the PTRF/Cavin-1 gene cause congenital generalized lipodystrophy type 4 (CGL4) associated with myopathy. Additionally, long-QT syndrome and fatal cardiac arrhythmia are observed in patients with CGL4 who have homozygous PTRF/Cavin-1 ...
Takuya Taniguchi, Naoki Maruyama, Takehiro Ogata, Takeru Kasahara, Naohiko Nakanishi, Kotaro Miyagawa, Daisuke Naito, Tetsuro Hamaoka, Masahiro Nishi, Satoaki Matoba, Tomomi Ueyama   +10 more
doaj   +1 more source

Gene and Protein Accumulation Changes Evoked in Porcine Aorta in Response to Feeding with Two Various Fructan Sources

Animals, 2022
In this study, two different ITFs sources were incorporated into a cereal-based diet to evaluate possible aortic protein and gene changes in nursery pigs.
Marta Marynowska, Agnieszka Herosimczyk, Adam Lepczyński, Marcin Barszcz, Adrianna Konopka, Aleksandra Dunisławska, Małgorzata Ożgo   +6 more
doaj   +1 more source

Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development

Frontiers in Physiology, 2020
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders.
Maider Varela-Guruceaga, Elise Belaidi, Lucie Lebeau, Ella Aka, Ramaroson Andriantsitohaina, Sophie Giorgetti-Peraldi, Claire Arnaud, Soazig Le Lay   +7 more
doaj   +1 more source

Galectin-3 Overrides PTRF/Cavin-1 Reduction of PC3 Prostate Cancer Cell Migration. [PDF]

PLoS ONE, 2015
Expression of Caveolin-1 (Cav1), a key component of cell surface caveolae, is elevated in prostate cancer (PCa) and associated with PCa metastasis and a poor prognosis for PCa patients.
Fanrui Meng, Bharat Joshi, Ivan Robert Nabi   +2 more
doaj   +1 more source

Molecular composition and ultrastructure of the caveolar coat complex.

PLoS Biology, 2013
Caveolae are an abundant feature of the plasma membrane of many mammalian cell types, and have key roles in mechano-transduction, metabolic regulation, and vascular permeability.
Alexander Ludwig, Gillian Howard, Carolina Mendoza-Topaz, Thomas Deerinck, Mason Mackey, Sara Sandin, Mark H Ellisman, Benjamin J Nichols   +7 more
doaj   +1 more source

Inhibition of Cavin3 Degradation by the Human Parainfluenza Virus Type 2 V Protein Is Important for Efficient Viral Growth

Frontiers in Microbiology, 2020
Cavin proteins have important roles in the formation of caveolae in lipid raft microdomains. Pulse-chase experiments of cells infected with human parainfluenza virus type 2 (hPIV-2) showed decreased proteasomal degradation of Cavin3.
Keisuke Ohta, Yusuke Matsumoto, Machiko Nishio   +2 more
doaj   +1 more source

MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes [PDF]

, 2009
Polymerase I and transcript release factor (PTRF)/Cavin is a cytoplasmic protein whose expression is obligatory for caveola formation. Using biochemistry and fluorescence resonance energy transfer–based approaches, we now show that a family of related ...
Nixon, S. J., Robert G. Parton, Liu, Libin, Susan J. Nixon, Lo, Harriet P., Abankwa, D, Vinten, Jorgen, Fernandez-Rojo, M, Walser, Piers J., Pilch, Paul F., Pilch, PF, John F. Hancock, Gygi, SP, Michele Bastiani, Hancock, JF, Gygi, S. P., Jedrychowski, MP, Gygi, Steven, Parton, Robert G., Walser, P. J., Paul F. Pilch, Vinten, J, Jedrychowski, Mark P., Michael R. Breen, Luetterforst, Robert, Michelle M. Hill, Kathryn N. North, Hancock, John F., Libin Liu, Nixon, Susan J., Hill, M. M., Hancock, J. F., Nixon, SJ, Jedrychowski, Mark, Breen, MR, Robert Luetterforst, Liu, L, Lo, H. P., Daniel Abankwa, Walser, PJ, Steven P. Gygi, Breen, M. R., Hill, Michelle M., Parton, RG, Luetterforst, R, Hill, MM, Piers J. Walser, Manuel Fernandez-Rojo, Bastiani, M, North, Kathryn N., Harriet P. Lo, Jedrychowski, M. P., Breen, Michael R., Gygi, Steven P., Jorgen Vinten, Parton, R. G., Abankwa, Daniel, Pilch, P. F., North, K. N., Bastiani, Michele, Lo, HP, North, KN, Fernandez-Rojo, Manuel, Mark P. Jedrychowski   +63 more
core   +1 more source

Endocytic crosstalk: cavins, caveolins, and caveolae regulate clathrin-independent endocytosis.

PLoS Biology, 2014
Several studies have suggested crosstalk between different clathrin-independent endocytic pathways. However, the molecular mechanisms and functional relevance of these interactions are unclear.
Natasha Chaudhary, Guillermo A Gomez, Mark T Howes, Harriet P Lo, Kerrie-Ann McMahon, James A Rae, Nicole L Schieber, Michelle M Hill, Katharina Gaus, Alpha S Yap, Robert G Parton   +10 more
doaj   +1 more source

Listeria monocytogenes Exploits Host Caveolin for Cell-to-Cell Spreading

mBio, 2020
Listeria monocytogenes moves from one cell to another using actin-rich membrane protrusions that propel the bacterium toward neighboring cells. Despite cholesterol being required for this transfer process, the precise host internalization mechanism ...
Aaron S. Dhanda, Connie Yu, Katarina T. Lulic, A. Wayne Vogl, Valentina Rausch, Diana Yang, Benjamin J. Nichols, Sung Hyun Kim, Simona Polo, Carsten G. Hansen, Julian A. Guttman   +10 more
doaj   +1 more source

The Effects of Cavin-2 on Angiogenesis [PDF]

, 2016
Caveolae are bulb-shaped invaginations about 50-60nm in size on the plasma membrane of mammalian cells that play a key role in cell signaling, endocytosis, plasma membrane adaptations, and lipid homeostasis.
Pogue, Connor Blaine
core   +1 more source