Results 91 to 100 of about 562,936 (248)
The Journal of Physiology, EarlyView.Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos +7 more
wiley +1 more source
Pharmacology Research &Perspectives, Volume 14, Issue 5, October 2026.β‐Caryophyllene is a multifunctional sesquiterpene with significant therapeutic potential. Our findings demonstrate that β‐caryophyllene exerts broad hepatoprotective effects through the activation of cannabinoid type 2 (CB2) receptors. These effects include suppression of oxidative stress–induced injury, attenuation of inflammatory responses ...
Lujain Bader Eddin +6 more
wiley +1 more source
European Neuropsychopharmacology, 2009 Cannabinoid CB1 inverse agonists suppress food-motivated behaviors, but may also induce psychiatric effects such as depression and anxiety. To evaluate behaviors potentially related to anxiety, the present experiments assessed the CB1 inverse agonist ...
K. Sink +9 more
semanticscholar +1 more source
Learning & memory (Cold Spring Harbor, N.Y.), 2006 The cannabinoid CB1 receptor has been shown to be critically involved in the extinction of fear memory. Systemic injection of a CB1 receptor antagonist prior to extinction training blocked extinction.
Hui-Ching Lin, Sheng-Chun Mao, P. Gean
semanticscholar +1 more source
Aging Cell, Volume 25, Issue 10, October 2026.Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley +1 more source
Efeito do canabidiol sobre a reconsolidação da memória de medo ao contexto: envolvimento dos receptores CB1 do córtex pré-límbico [PDF]
, 2014 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A busca por drogas que prejudicam a reconsolidação de memórias traumáticas pode ter um impacto ...
Stern, Cristina Aparecida Jark
core
Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor [PDF]
, 2016 The cannabinoid CB1 receptor is a G protein coupled receptor and plays an important role in many biological processes and physiological functions. A variety of CB1 receptor agonists and antagonists, including endocannabinoids, phytocannabinoids, and ...
Li, Jun‐Xu +5 more
core +1 more source
Glucose concentration in culture medium affects mRNA expression of TRPV1 and CB1 receptors and changes capsaicin toxicity in PC12 cells [PDF]
Iranian Journal of Basic Medical Sciences, 2014 Objective (s):Hyperglycemia is widely recognized as the underlying cause for some debilitating conditions in diabetic patients. The role of cannabinoid CB1 and vanilloid TRPV1 receptors and their endogenous agonists, endovanilloids, in diabetic ...
Ahmad Mohammadi-Farani +2 more
doaj
Lipoxina A4: um modulador alostérico endocanabinóide no sistema nervoso central [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciênicas Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2010Lipoxinas e endocanabinóides são eicosanóides endógenos que são liberados sob demanda em resposta à ...
Pamplona, Fabrício Alano
core
Inhaled corticosteroids versus long-acting beta2-agonists for chronic obstructive pulmonary disease [PDF]
, 2011 Background Long-acting beta2-agonists and inhaled corticosteroids can be used as maintenance therapy by patients with moderate to severe chronic obstructive pulmonary disease. These interventions are often taken together in a combination inhaler. However,
David J Evans +12 more
core +1 more source