Assessment of Cannabidiol Supplements Use in Small Animals Practice in Portugal
ABSTRACT This study aimed to assess the current use of cannabidiol supplements (CBDS) by Portuguese small animal veterinary practitioners. An anonymous online survey questioning the frequency of CBDS use, purpose of use and the perceived outcome was developed using Microsoft Forms, and targeted veterinarians currently working in small animal clinics in
Maria Inês Santos, Ana Luísa Lourenço
wiley +1 more source
Efeitos do antagonismo de receptores CB1 sobre a consolidação da memória de medo contextual em diferentes períodos do ritmo circadiano [PDF]
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.O ritmo circadiano sincroniza as fases inativa e ativa do organismo com a luminosidade do ...
Silva, Rafael Scoz
core
Heterodimerization of apelin receptor and neurotensin receptor 1 induces phosphorylation of ERK1/2and cell proliferationviaGαq-mediated mechanism [PDF]
Dimerization of G protein-coupled receptors (GPCRs) is crucial for receptor function including agonist affinity, efficacy, trafficking and specificity of signal transduction, including G protein coupling.
Cai, X +9 more
core +1 more source
Maternal obesity during lactation as a hypertensive cardiovascular risk factor in the offspring
Abstract Maternal obesity is a major public health concern, with growing evidence supporting its role in the developmental programming of cardiometabolic disease. Although prenatal mechanisms have been investigated extensively, the contribution of lactation as a postnatal window of cardiovascular (CV) programming remains insufficiently understood ...
Gabriela Arenas +2 more
wiley +1 more source
The Neuroprotective Effect of Cannabinoid Receptor Agonist (WIN55,212-2) in Paraoxon Induced Neurotoxicity in PC12 Cells and N-methyl-D-aspartate Receptor Interaction [PDF]
Objective: Considering that cannabinoids protect neurons against neurodegeneration, inthis study, the neuroprotective effect of WIN55,212-2 in paraoxon induced neurotoxicity inPC12 cells and the role of the N-methyl-D-aspartate (NMDA) receptor were ...
Hedayat Sahraei +4 more
doaj
Abstract This study investigated Prangos ferulacea (PF)‐induced hepatotoxicity, its potential association with endoplasmic reticulum (ER) stress and proinflammatory cytokines, and the effect of the cannabinoid type 2 receptor agonist JWH‐133. Rats (n = 37) were divided into four groups: control–sham group (CSG, n = 9), PF extract group (PG, n = 9), PF ...
Mesut Çelik +7 more
wiley +1 more source
Efeito do canabidiol sobre a reconsolidação da memória de medo ao contexto: envolvimento dos receptores CB1 do córtex pré-límbico [PDF]
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2014.A busca por drogas que prejudicam a reconsolidação de memórias traumáticas pode ter um impacto ...
Stern, Cristina Aparecida Jark
core
Untersuchungen zur Rolle des endogenen Cannabinoidsystems bei der Anpassung an aversive Situationen [PDF]
Ziel der vorliegenden Arbeit war es zu untersuchen, auf welche Art und Weise das endogene Cannabinoidsystem die Extinktion konditionierter Furcht vermittelt. Dabei gliedert sich diese Arbeit in vier Teile.
Kamprath, Kornelia
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Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone +1 more
wiley +1 more source
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos +7 more
wiley +1 more source

