Results 101 to 110 of about 1,257,507 (228)
Cannabinoid receptor type-1: breaking the dogmas [version 1; referees: 3 approved]
F1000Research, 2016 The endocannabinoid system (ECS) is abundantly expressed in the brain. This system regulates a plethora of physiological functions and is composed of cannabinoid receptors, their endogenous ligands (endocannabinoids), and the enzymes involved in the ...
Arnau Busquets Garcia +3 more
doaj +1 more source
Taurine and Metabolic Diseases: Molecular Mechanisms and Therapeutic Implications
Food Frontiers, Volume 7, Issue 5, September 2026.The dietary sources of taurine, as well as its protective effects and mechanisms in metabolism‐related diseases and metabolic disorder–associated ocular and cerebral injuries. ABSTRACT Taurine (Tau) is a sulfur‐containing amino acid prevalent in animal tissues and primarily acquired through dietary sources.
Xiaojie Ma, Zhijian Rao, Lifang Zheng
wiley +1 more source
, 2007 Endocannabinoids are lipid signaling mediators that exert an important neuromodulatory role and confer neuroprotection in several types of brain injury.
Monory, Krisztina +8 more
core +1 more source
Effects of Cannabinoid Receptor Interacting Protein (CRIP1a) on Cannabinoid Receptor (CB1) Function [PDF]
, 2009 EFFECTS OF CANNABINOID RECEPTOR INTERACTING PROTEIN (CRIP1a) ON CANNABINOID (CB1) RECEPTOR FUNCTION. By Tricia Hardt Smith, B.S., M.S. A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia ...
Smith, Tricia
core +1 more source
Glia, Volume 74, Issue 9, September 2026.Proinflammatory activation reorganizes microglial A2A and CB2 receptors, promoting their incorporation into stable heteromers and blocking agonist‐induced redistribution. The results reveal those heteromers as potential therapeutic targets in inflammatory contexts.
Rafael Franco +4 more
wiley +1 more source
Transmembrane Helical Domain of the Cannabinoid CB1 Receptor [PDF]
, 2009 Brain cannabinoid (CB1) receptors are G-protein coupled receptors and belong to the rhodopsin-like subfamily. A homology model of the inactive state of the CB1 receptor was constructed using the x-ray structure of β2-adrenergic receptor (β2AR) as the ...
Shim, Joong-Youn
core +1 more source
The Role of Hippocampal Interneuron Migration in Neurodevelopmental Disorders: A Systematic Review
Hippocampus, Volume 36, Issue 5, September 2026.ABSTRACT Hippocampal abnormalities are frequently associated with neurodevelopmental disorders as interneurons are crucial in establishing the network connectivity of neurons. This systematic review analyzed primary literature with a focus on aberrant hippocampal interneuron migration as an etiology for neurodevelopmental disorders, summarizing the ...
M. A. C. Till +3 more
wiley +1 more source
Human Psychopharmacology: Clinical and Experimental, Volume 41, Issue 5, September 2026.ABSTRACT Objective This review critically examines psilocybin, with particular emphasis on its pharmacokinetics and pharmacodynamics, including its serotonergic, neuroplastic, and anti‐inflammatory mechanisms. It integrates historical context, preclinical and clinical evidence, and evaluates emerging therapeutic potential, safety, microdosing practices,
José Norberto Vásquez‐Bonilla
wiley +1 more source
Interação entre os sistemas endocanabinóide e glicocorticóide na extinção do condicionamento aversivo contextual em ratos [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas. Programa de Pós-Graduação em FarmacologiaA regulação das respostas emocionais é essencial para a saúde mental e a forma mais simples de regulação destas respostas é
Bitencourt, Rafael Mariano de
core
Metabolic Syndrome: From Mechanisms to Therapeutic Interventions
MedComm, Volume 7, Issue 9, September 2026.A comprehensive overview of molecular mechanisms delves into the potential disease mechanisms of metabolic syndrome, including complex mechanisms such as insulin resistance, chronic low‐grade inflammation, oxidative stress, and epigenetic modifications, and how these mechanisms contribute to the development of metabolic syndrome. Here, the relationship
Mengyao Yan, Qian Xiang
wiley +1 more source