Results 121 to 130 of about 25,158 (238)

Distribution of CB1 cannabinoid receptors and their relationship with mu-opioid receptors in the rat periaqueductal gray

open access: yes, 2012
► CB1 receptor expression is diffuse and extensive in the periaqueductal gray (PAG). ► The mu-opioid peptide (MOP) and CB1 receptors co-localize in many PAG neurons.
Hegarty, D.M   +3 more
core   +1 more source

Short‐Term Daily Oral Administration of Cannabidiol Does Not Impact Rebound Tonometry Intraocular Pressure or Schirmer Tear Test Values in Healthy Adult Horses

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective To assess the effect of orally administered cannabidiol (CBD) on TonoVet measured intraocular pressure (IOP) and Schirmer tear test I (STT) in horses. Animal Studied Horse. Procedure This was a masked, randomized, balanced cross‐over study of six healthy adult horses.
Kathryn Diehl   +2 more
wiley   +1 more source

Untersuchungen zur Rolle des endogenen Cannabinoidsystems bei der Anpassung an aversive Situationen

open access: yes, 2006
Ziel der vorliegenden Arbeit war es zu untersuchen, auf welche Art und Weise das endogene Cannabinoidsystem die Extinktion konditionierter Furcht vermittelt. Dabei gliedert sich diese Arbeit in vier Teile.
Kamprath, Kornelia
core  

Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes

open access: yes, 2013
Type-1 cannabinoid (CB1) receptors and leptin receptors (ObR) have been recently and independently shown to directly regulate astroglial functions. Using a series of in vitro experiments, this study demonstrates that the functions of ObR are tightly ...
Cardinal, Pierre   +17 more
core   +1 more source

Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model

open access: yesThe FASEB Journal, Volume 40, Issue 12, 30 June 2026.
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva   +3 more
wiley   +1 more source

Transmembrane Helical Domain of the Cannabinoid CB1 Receptor [PDF]

open access: yesBiophysical Journal, 2009
Brain cannabinoid (CB(1)) receptors are G-protein coupled receptors and belong to the rhodopsin-like subfamily. A homology model of the inactive state of the CB(1) receptor was constructed using the x-ray structure of beta(2)-adrenergic receptor (beta(2)AR) as the template.
openaire   +2 more sources

Cannabigerol Alleviates Obesity‐Induced Mitochondrial Dysfunction by Cardiolipin Fatty Acid Remodeling

open access: yesThe FASEB Journal, Volume 40, Issue 11, 15 June 2026.
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec   +3 more
wiley   +1 more source

The regulation of endocannabinoids after neuronal damage and the neuroprotective impact of GPR55 in organotypic hippocampal slice cultures

open access: yes, 2013
Endocannabinoids (eCB) are signaling lipids and became known for their importance in the central nervous system as well as in immune defense. Beneficial effects of eCB are shown in processes of excitotoxic lesion, secondary damage and neuronal plasticity
Kallendrusch, Sonja
core  

Elucidating Immune Cell Mediated Causal Pathways Linking Blood Metabolites to Major Depressive Disorder: A Mediation Mendelian Randomization Analysis

open access: yesBrain and Behavior, Volume 16, Issue 6, June 2026.
Our integrative Mendelian randomization framework revealed that specific circulating metabolites exert causal effects on major depressive disorder, partly through immune‐cell–mediated pathways. These findings highlight metabolite–immune interactions as potential mechanistic targets for MDD prevention and therapy.
Zhiwei Xu   +8 more
wiley   +1 more source

Dandruff Is a Low‐Grade Inflammatory Condition Featuring Hyperproliferative Keratinocytes, Interleukin‐17‐Producing T Cells, and N‐Acyl Ethanolamines

open access: yesImmunity, Inflammation and Disease, Volume 14, Issue 6, June 2026.
ABSTRACT Background Dandruff features epidermal scaling but lacks overt signs of inflammation, such as erythema. Characterisation of its inflammatory profile may improve understanding of the underlying inflammatory mechanisms and therefore indicate alternative approaches for treatment.
Alexandra C. Kendall   +8 more
wiley   +1 more source

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