Results 121 to 130 of about 25,158 (238)
► CB1 receptor expression is diffuse and extensive in the periaqueductal gray (PAG). ► The mu-opioid peptide (MOP) and CB1 receptors co-localize in many PAG neurons.
Hegarty, D.M +3 more
core +1 more source
ABSTRACT Objective To assess the effect of orally administered cannabidiol (CBD) on TonoVet measured intraocular pressure (IOP) and Schirmer tear test I (STT) in horses. Animal Studied Horse. Procedure This was a masked, randomized, balanced cross‐over study of six healthy adult horses.
Kathryn Diehl +2 more
wiley +1 more source
Untersuchungen zur Rolle des endogenen Cannabinoidsystems bei der Anpassung an aversive Situationen
Ziel der vorliegenden Arbeit war es zu untersuchen, auf welche Art und Weise das endogene Cannabinoidsystem die Extinktion konditionierter Furcht vermittelt. Dabei gliedert sich diese Arbeit in vier Teile.
Kamprath, Kornelia
core
Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes
Type-1 cannabinoid (CB1) receptors and leptin receptors (ObR) have been recently and independently shown to directly regulate astroglial functions. Using a series of in vitro experiments, this study demonstrates that the functions of ObR are tightly ...
Cardinal, Pierre +17 more
core +1 more source
Don't Sweat It: Cannabinoid CB1 Receptors Reduce Sweating in a Mouse Model
A new galvanic skin response‐based approach offers a simple method for measuring sweating in the paws of mice. This method is used to demonstrate that cannabinoid CB1 receptors reduce baseline sweating in mice, likely via inhibition of sympathetic acetylcholine release via axonal CB1 receptors.
Natalia Murataeva +3 more
wiley +1 more source
Transmembrane Helical Domain of the Cannabinoid CB1 Receptor [PDF]
Brain cannabinoid (CB(1)) receptors are G-protein coupled receptors and belong to the rhodopsin-like subfamily. A homology model of the inactive state of the CB(1) receptor was constructed using the x-ray structure of beta(2)-adrenergic receptor (beta(2)AR) as the template.
openaire +2 more sources
Graphical overview of the effects of the high‐fat, high‐sucrose (HFHS) diet regime and 2‐week cannabigerol (CBG) treatment on the intramuscular long‐chain fatty acids (LCFAs) trafficking and lipid metabolism, with subsequent implications for mitochondrial cardiolipin (CL) composition in the red gastrocnemius muscle.
Patrycja Bielawiec +3 more
wiley +1 more source
Endocannabinoids (eCB) are signaling lipids and became known for their importance in the central nervous system as well as in immune defense. Beneficial effects of eCB are shown in processes of excitotoxic lesion, secondary damage and neuronal plasticity
Kallendrusch, Sonja
core
Our integrative Mendelian randomization framework revealed that specific circulating metabolites exert causal effects on major depressive disorder, partly through immune‐cell–mediated pathways. These findings highlight metabolite–immune interactions as potential mechanistic targets for MDD prevention and therapy.
Zhiwei Xu +8 more
wiley +1 more source
ABSTRACT Background Dandruff features epidermal scaling but lacks overt signs of inflammation, such as erythema. Characterisation of its inflammatory profile may improve understanding of the underlying inflammatory mechanisms and therefore indicate alternative approaches for treatment.
Alexandra C. Kendall +8 more
wiley +1 more source

