Results 51 to 60 of about 97,974 (286)

Role of CC chemokine CCL6/C10 as a monocyte chemoattractant in a murine acute peritonitis

Mediators of Inflammation, 2004
THE aim of this study was to determine the role of CC chemokine CCL6/C10 in acute inflammation. Intraperitoneal injection of thioglycollate increased peritoneal CCL6, which peaked at 4 h and remained elevated at 48 h. Neutralization of CCL6 significantly
Andrew M. LaFleur, Nicholas W. Lukacs, Steven L. Kunkel, Akihiro Matsukawa   +3 more
doaj   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang, Yujie Liu, Fei Li, Xuelin Li, Lanlan Li, Jie Zhang, Yali Xu   +6 more
wiley   +1 more source

Silent chemoattractant receptors : D6 as a decoy and scavenger receptor for inflammatory CC chemokines

, 2005
The chemokine system includes at least three "silent" receptors, DARC, D6 and CCX CKR, with distinct specificity and tissue distribution. D6 binds most inflammatory, but not homeostatic, CC chemokines and shuttles in a ligand-independent way from the ...
Y. Martinez de la Torre, Emanuela Galliera, G. Vago, Alberto Mantovani, Annunciata Vecchi, Gianluca Vago, Haribabu Bodduluri, A. Mantovani, Massimo Locati, H. Bodduluri, Yeny Martinez de la Torre, Raffaella Bonecchi, M. Locati, E.R. Galliera, R. Bonecchi, A. Vecchi   +15 more
core   +1 more source

Advances in chemokines of teleost fish species

Aquaculture and Fisheries
In mammals, chemokines are a superfamily of cytokines that regulate cell migration or exert direct antimicrobial activity. The presence and organization of four invariant cysteine residues within the mature protein sequence can classify chemokines into ...
Hongsen Xu, Fuguo Liu
doaj   +1 more source

Extensive expansion and diversification of the chemokine gene family in zebrafish: Identification of a novel chemokine subfamily CX

BMC Genomics, 2008
Background The chemokine family plays important roles in cell migration and activation. In humans, at least 44 members are known. Based on the arrangement of the four conserved cysteine residues, chemokines are now classified into four subfamilies, CXC ...
Tanase Sumio, Kikuchi Yutaka, Yoshizawa Akio, Takegawa Sumio, Izawa Toshiaki, Otsuka-Ono Kaori, Kato-Unoki Yoko, Osada Naoki, Hieshima Kunio, Nomiyama Hisayuki, Miura Retsu, Kusuda Jun, Nakao Miki, Yoshie Osamu   +13 more
doaj   +1 more source

Marked Long‐Term Improvement in Lung Function in Melanoma Differentiation–Associated Protein 5 Antibody–Positive Dermatomyositis Patients: Experience of a Single‐Center Longitudinal Cohort in North America

Arthritis Care &Research, EarlyView.
Objective The objective of this study was to describe the longitudinal disease course and pulmonary outcomes of North American patients with melanoma differentiation–associated protein 5 (MDA5) antibody–associated dermatomyositis (DM). Methods Thirty patients with MDA5 antibody–associated DM were identified in a single‐center longitudinal cohort of 352
Jenice X. Cheah, Sangmee S. Bae, Tiffany De Leon, Yuna Lee, Rong Guo, David Elashoff, Jennifer Wang, Ani Shahbazian, Christina Charles‐Schoeman   +8 more
wiley   +1 more source

Effect of CC chemokines on mediator release from human skin mast cells and basophils

, 1995
Chemokines are considered important mediators of various inflammatory processes. In human basophils, different CC chemokines are known to stimulate release of histamine and generation of leukotriene (LT)C4.
Czarnetzki, B. M., Zuberbier, T., Beiglböck, F., Hartmann, K.   +3 more
core   +1 more source

Pull‐and‐Push Nanotherapeutic Hydrogels: Scavenging Inflammatory Triggers While Driving Tissue Regeneration in Burn Wounds

Advanced Functional Materials, EarlyView.
A nanounit‐assembled hydrogel employing a “pull‐and‐push” strategy simultaneously scavenges pro‐inflammatory cell‐free DNA (cfDNA) and delivers regenerative therapeutics in response to burn‐induced hyperthermia. By repolarizing macrophages and promoting angiogenesis, this multifunctional platform accelerates burn wound healing, offering a blueprint for
Han‐Sem Kim, Seong‐Jin Shin, Sak Lee, Nandin Mandakhbayar, Ji‐Hye Kang, Da‐Young Kong, Seong‐Doo Hong, Ueon Sang Shin, Hae‐Won Kim, Jung‐Hwan Lee   +9 more
wiley   +1 more source

Expression of inducible CC chemokines in rainbow trout (Oncorhynchus mykiss) in response to a viral haemorrhagic septicemia virus (VHSV) DNA vaccine and interleukin 8

, 2007
In rainbow trout (Oncorhynchus mykiss), at least three CXC chemokines and eighteen CC chemokine sequences have been discovered in the past years, although no studies concerning their bioactivity have been performed yet.
Coll Morales, Julio, Sanchez, Esther, Tafalla, Carolina   +2 more
core   +1 more source

Structure and function of A41, a vaccinia virus chemokine binding protein.

PLoS Pathogens, 2008
The vaccinia virus (VACV) A41L gene encodes a secreted 30 kDa glycoprotein that is nonessential for virus replication but affects the host response to infection.
Mohammad W Bahar, Julia C Kenyon, Mike M Putz, Nicola G A Abrescia, James E Pease, Emma L Wise, David I Stuart, Geoffrey L Smith, Jonathan M Grimes   +8 more
doaj   +1 more source