Results 31 to 40 of about 97,974 (286)
Chemokine-induced phosphorylation of CC chemokine receptor 5 (CCR5) [PDF]
Abstract The CC-chemokine receptor 5 (CCR5) mediates activation of T lymphocytes and macrophages by chemokines and is a major co-receptor for macrophage-tropic HIV-1 strains. Recently, it was shown that the natural CCR5 ligands RANTES, macrophage inflammatory protein-1á (MIP-1á), MIP-1β, and amino-terminal modifications of RANTES (Met ...
H, Olbrich, A E, Proudfoot, M, Oppermann
openaire +2 more sources
The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3 [PDF]
We cloned the mouse homologue of the chemokine receptor CXCR3, which is located in mouse chromosome X. We screened a large panel of chemokines for their ability to induce a calcium flux in mouse CXCR3-transfected cells and identified a new ligand for this receptor, the recently reported CC chemokine 6Ckine. This represents an example of a CC chemokine,
H, Soto +7 more
openaire +2 more sources
Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines [PDF]
Bronchogenic carcinoma is the leading cause of malignancy-related mortality in the United States, with an overall 5-year survival rate of less than 15%.
DiGiovine, Bruno +7 more
core +1 more source
HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets. [PDF]
Carriage of the genetic combination encoding a high expression inhibitory Killer Immunoglobulin-like Receptor (KIR)3DL1 with its ligand, HLA-B*57 (*h/*y+B*57) is associated with slower time to AIDS and better HIV viral load control than being a Bw6 ...
Rujun Song +5 more
doaj +1 more source
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif +7 more
doaj +1 more source
CC-chemokine receptors: a potential therapeutic target for Trypanosoma cruzi-elicited myocarditis
The comprehension of the pathogenesis of Trypanosoma cruzi-elicited myocarditis is crucial to delineate new therapeutic strategies aiming to ameliorate the inflammation that leads to heart dysfunction, without hampering parasite control.
APMP Marino +6 more
doaj +1 more source
CC chemokines in zebrafish: Evidence for extensive intrachromosomal gene duplications
Chemokines are a family of structurally related chemotactic cytokines that regulate the migration of leukocytes. CC chemokines represent the largest subfamily of chemokines, with 28 genes in mammals.
Liu, Zhanjiang +3 more
core +1 more source
Novel lymphocyte-specific CC chemokines and their receptors
By using a cloning method termed the signal sequence trap as well as by searching for chemokine homologous sequences in the database of expressed sequence tags, cDNA fragments potentially encoding novel CC chemokines were initially identified.
Osamu Yoshie +2 more
core +1 more source
Association of CC chemokines with Breast Cancer Disparity
Despite recent advances, breast cancer (BrCa) still affects many women, and the impact is disproportional in African Americans (AA) compared to European Americans (EA).
Singh, Shailesh +2 more
core
Chemokines are a large family of small cytokines and generally have low molecular weight ranging from 7 to 15kDa. Chemokines and their receptors are able to control the migration and residence of all immune cells.
Diana Carolina Torres Palomino +1 more
doaj +1 more source

