Results 31 to 40 of about 97,974 (286)

Chemokine-induced phosphorylation of CC chemokine receptor 5 (CCR5) [PDF]

open access: yesJournal of Leukocyte Biology, 1999
Abstract The CC-chemokine receptor 5 (CCR5) mediates activation of T lymphocytes and macrophages by chemokines and is a major co-receptor for macrophage-tropic HIV-1 strains. Recently, it was shown that the natural CCR5 ligands RANTES, macrophage inflammatory protein-1á (MIP-1á), MIP-1β, and amino-terminal modifications of RANTES (Met ...
H, Olbrich, A E, Proudfoot, M, Oppermann
openaire   +2 more sources

The CC chemokine 6Ckine binds the CXC chemokine receptor CXCR3 [PDF]

open access: yesProceedings of the National Academy of Sciences, 1998
We cloned the mouse homologue of the chemokine receptor CXCR3, which is located in mouse chromosome X. We screened a large panel of chemokines for their ability to induce a calcium flux in mouse CXCR3-transfected cells and identified a new ligand for this receptor, the recently reported CC chemokine 6Ckine. This represents an example of a CC chemokine,
H, Soto   +7 more
openaire   +2 more sources

Macrophage infiltration in human non-small-cell lung cancer: the role of CC chemokines [PDF]

open access: yes, 2000
 Bronchogenic carcinoma is the leading cause of malignancy-related mortality in the United States, with an overall 5-year survival rate of less than 15%.
DiGiovine, Bruno   +7 more
core   +1 more source

HIV protective KIR3DL1/S1-HLA-B genotypes influence NK cell-mediated inhibition of HIV replication in autologous CD4 targets. [PDF]

open access: yesPLoS Pathogens, 2014
Carriage of the genetic combination encoding a high expression inhibitory Killer Immunoglobulin-like Receptor (KIR)3DL1 with its ligand, HLA-B*57 (*h/*y+B*57) is associated with slower time to AIDS and better HIV viral load control than being a Bw6 ...
Rujun Song   +5 more
doaj   +1 more source

Chemokine-Binding Proteins Encoded by Parapoxvirus of Red Deer of New Zealand Display Evidence of Gene Duplication and Divergence of Ligand Specificity

open access: yesFrontiers in Microbiology, 2019
Parapoxvirus of red deer in New Zealand (PVNZ) is a species of the Parapoxvirus genus that causes pustular dermatitis. We identified a cluster of genes in PVNZ that encode three unique chemokine-binding proteins (CBPs) namely ORF112.0, ORF112.3 and ...
Saeed Sharif   +7 more
doaj   +1 more source

CC-chemokine receptors: a potential therapeutic target for Trypanosoma cruzi-elicited myocarditis

open access: yesMemorias do Instituto Oswaldo Cruz, 2005
The comprehension of the pathogenesis of Trypanosoma cruzi-elicited myocarditis is crucial to delineate new therapeutic strategies aiming to ameliorate the inflammation that leads to heart dysfunction, without hampering parasite control.
APMP Marino   +6 more
doaj   +1 more source

CC chemokines in zebrafish: Evidence for extensive intrachromosomal gene duplications

open access: yes, 2006
Chemokines are a family of structurally related chemotactic cytokines that regulate the migration of leukocytes. CC chemokines represent the largest subfamily of chemokines, with 28 genes in mammals.
Liu, Zhanjiang   +3 more
core   +1 more source

Novel lymphocyte-specific CC chemokines and their receptors

open access: yes, 1997
By using a cloning method termed the signal sequence trap as well as by searching for chemokine homologous sequences in the database of expressed sequence tags, cDNA fragments potentially encoding novel CC chemokines were initially identified.
Osamu Yoshie   +2 more
core   +1 more source

Association of CC chemokines with Breast Cancer Disparity

open access: yes, 2023
Despite recent advances, breast cancer (BrCa) still affects many women, and the impact is disproportional in African Americans (AA) compared to European Americans (EA).
Singh, Shailesh   +2 more
core  

Chemokines and immunity

open access: yesEinstein (São Paulo)
Chemokines are a large family of small cytokines and generally have low molecular weight ranging from 7 to 15kDa. Chemokines and their receptors are able to control the migration and residence of all immune cells.
Diana Carolina Torres Palomino   +1 more
doaj   +1 more source

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