Results 101 to 110 of about 5,303,548 (144)

Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites. [PDF]

Genes Chromosomes Cancer, 2021
Atkin ND, Raimer HM, Wang Z, Zang C, Wang YH.   +4 more
europepmc   +1 more source

A negatively charged region within carboxy-terminal domain maintains proper CTCF DNA binding

iScience
Summary: As an essential regulator of higher-order chromatin structures, CCCTC-binding factor (CTCF) is a highly conserved protein with a central DNA-binding domain of 11 tandem zinc fingers (ZFs), which are flanked by amino (N-) and carboxy (C ...
Lian Liu, Yuanxiao Tang, Yan Zhang, Qiang Wu   +3 more
doaj   +1 more source

The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation

Nature Communications
CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify the functions of protein to regulate numerous cellular ...
Xiuxiao Tang, Pengguihang Zeng, Kezhi Liu, Li Qing, Yifei Sun, Xinyi Liu, Lizi Lu, Chao Wei, Jia Wang, Shaoshuai Jiang, Jun Sun, Wakam Chang, Haopeng Yu, Hebing Chen, Jiaguo Zhou, Chengfang Xu, Lili Fan, Yi-Liang Miao, Junjun Ding   +18 more
doaj   +1 more source

TEAD2 initiates ground-state pluripotency by mediating chromatin looping

The EMBO Journal
The transition of mouse embryonic stem cells (ESCs) between serum/LIF and 2i(MEK and GSK3 kinase inhibitor)/LIF culture conditions serves as a valuable model for exploring the mechanisms underlying ground and confused pluripotent states.
Rong Guo, Xiaotao Dong, Feng Chen, Tianrong Ji, Qiannan He, Jie Zhang, Yingliang Sheng, Yanjiang Liu, Shengxiong Yang, Weifang Liang, Yawei Song, Ke Fang, Lingling Zhang, Gongcheng Hu, Hongjie Yao   +14 more
doaj   +1 more source

The CCCTC Binding Factor, CTRL2, Modulates Heterochromatin Deposition and the Establishment of Herpes Simplex Virus 1 Latency In Vivo. [PDF]

J Virol, 2019
Washington SD, Singh P, Johns RN, Edwards TG, Mariani M, Frietze S, Bloom DC, Neumann DM.   +7 more
europepmc   +1 more source

The transcriptional regulator CCCTC-binding factor limits oxidative stress in endothelial cells. [PDF]

J Biol Chem, 2018
Roy AR, Ahmed A, DiStefano PV, Chi L, Khyzha N, Galjart N, Wilson MD, Fish JE, Delgado-Olguín P.   +8 more
europepmc   +1 more source

The human milk oligosaccharide 3′sialyllactose reduces low-grade inflammation and atherosclerosis development in mice

JCI Insight
Macrophages contribute to the induction and resolution of inflammation and play a central role in chronic low-grade inflammation in cardiovascular diseases caused by atherosclerosis.
Ariane R. Pessentheiner, Nathanael J. Spann, Chloe A. Autran, Tae Gyu Oh, Kaare V. Grunddal, Joanna K.C. Coker, Chelsea D. Painter, Bastian Ramms, Austin W.T. Chiang, Chen-Yi Wang, Jason Hsiao, Yiwen Wang, Anthony Quach, Laela M. Booshehri, Alexandra Hammond, Chiara Tognaccini, Joanna Latasiewicz, Lisa Willemsen, Karsten Zengler, Menno P.J. de Winther, Hal M. Hoffman, Martin Philpott, Adam P. Cribbs, Udo Oppermann, Nathan E. Lewis, Joseph L. Witztum, Ruth Yu, Annette R. Atkins, Michael Downes, Ron M. Evans, Christopher K. Glass, Lars Bode, Philip L.S.M. Gordts   +32 more
doaj   +1 more source

Analysis of the SH3-Domain Kinase Binding Protein 1 Predictive Model for Pancreatic Ductal Adenocarcinoma and CCCTC-Binding Factor Transcriptional Regulatory Study. [PDF]

World J Oncol
Sun RZ, Qiao KP, Xu XL, Chen YH, Meng J.
europepmc   +1 more source

CCCTC-binding factor regulates splicing factor proline and glutamine-rich to promote malignant growth of osteosarcoma. [PDF]

Am J Transl Res
Li D, Yang Y, Yin Z, Mao L, Zhang Y, Jiang P, Zhu T, He T, Zhong X, Zheng Q, Zhang W.   +10 more
europepmc   +1 more source