Results 101 to 110 of about 6,498 (147)

Inhibition of CCCTC Binding Factor-Programmed Cell Death Ligand 1 Axis Suppresses Emergence of Chemoresistance Induced by Gastric Cancer-Derived Mesenchymal Stem Cells. [PDF]

Front Immunol, 2022
Wang Q, Huang C, Ding Y, Wen S, Wang X, Guo S, Gao Q, Chen Z, Zhao Y, Wang M, Shen B, Zhu W.   +11 more
europepmc   +1 more source

The CCCTC-binding factor CTCF represses hepatitis B virus enhancer I and regulates viral transcription. [PDF]

Cell Microbiol, 2021
D'Arienzo V, Ferguson J, Giraud G, Chapus F, Harris JM, Wing PAC, Claydon A, Begum S, Zhuang X, Balfe P, Testoni B, McKeating JA, Parish JL.   +12 more
europepmc   +1 more source

Variants on the UBE2L3/YDJC Autoimmune Disease Risk Haplotype Increase UBE2L3 Expression by Modulating CCCTC-Binding Factor and YY1 Binding. [PDF]

Arthritis Rheumatol, 2022
Gopalakrishnan J, Tessneer KL, Fu Y, Pasula S, Pelikan RC, Kelly JA, Wiley GB, Gaffney PM.   +7 more
europepmc   +1 more source

Assessing acute myeloid leukemia susceptibility in rearrangement-driven patients by DNA breakage at topoisomerase II and CCCTC-binding factor/cohesin binding sites. [PDF]

Genes Chromosomes Cancer, 2021
Atkin ND, Raimer HM, Wang Z, Zang C, Wang YH.   +4 more
europepmc   +1 more source

A negatively charged region within carboxy-terminal domain maintains proper CTCF DNA binding

iScience
Summary: As an essential regulator of higher-order chromatin structures, CCCTC-binding factor (CTCF) is a highly conserved protein with a central DNA-binding domain of 11 tandem zinc fingers (ZFs), which are flanked by amino (N-) and carboxy (C ...
Lian Liu, Yuanxiao Tang, Yan Zhang, Qiang Wu   +3 more
doaj   +1 more source

The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation

Nature Communications
CCCTC-binding factor (CTCF), a ubiquitously expressed and highly conserved protein, is known to play a critical role in chromatin structure. Post-translational modifications (PTMs) diversify the functions of protein to regulate numerous cellular ...
Xiuxiao Tang, Pengguihang Zeng, Kezhi Liu, Li Qing, Yifei Sun, Xinyi Liu, Lizi Lu, Chao Wei, Jia Wang, Shaoshuai Jiang, Jun Sun, Wakam Chang, Haopeng Yu, Hebing Chen, Jiaguo Zhou, Chengfang Xu, Lili Fan, Yi-Liang Miao, Junjun Ding   +18 more
doaj   +1 more source

Cohesin mediates transcriptional insulation by CCCTC-binding factor

Cohesin mediates transcriptional insulation by CCCTC-binding factor
identifier:oai:t2r2.star.titech.ac.jp ...
openaire   +1 more source

Investigating the role of CCCTC-binding factor in osteoarthritis pathogenesis [PDF]

Osteoarthritis and Cartilage, 2018
openaire   +1 more source

TEAD2 initiates ground-state pluripotency by mediating chromatin looping

The EMBO Journal
The transition of mouse embryonic stem cells (ESCs) between serum/LIF and 2i(MEK and GSK3 kinase inhibitor)/LIF culture conditions serves as a valuable model for exploring the mechanisms underlying ground and confused pluripotent states.
Rong Guo, Xiaotao Dong, Feng Chen, Tianrong Ji, Qiannan He, Jie Zhang, Yingliang Sheng, Yanjiang Liu, Shengxiong Yang, Weifang Liang, Yawei Song, Ke Fang, Lingling Zhang, Gongcheng Hu, Hongjie Yao   +14 more
doaj   +1 more source

An upstream secondary DNA motif within the IL3 insulator CTCF binding site is required for enhancer-blocking insulator activity.

PLoS ONE
CCCTC-binding Factor (CTCF) is the only known vertebrate protein that functions to organise the genome into distinct functional chromatin domains. A subset of CTCF sites also provide insulator activity and barrier activity to block inappropriate enhancer-
Sarion R Bowers, Peter N Cockerill
doaj   +1 more source