Results 41 to 50 of about 11,477 (173)

Role of CCL11 in Eosinophilic Lung Disease during Respiratory Syncytial Virus Infection [PDF]

open access: yesJournal of Virology, 2005
ABSTRACTRespiratory syncytial virus (RSV) is a major viral pathogen of infants and the elderly. Significant morbidity is caused by an overexuberant mixed lung cell infiltrate, which is thought to be driven by chemokines. One of the main chemotactic mediators responsible for the movement of eosinophils is CCL11 (eotaxin).
Matthews, Stephen P.   +4 more
openaire   +3 more sources

Eotaxin-1 (CCL11) up-regulation in tears during seasonal allergic conjunctivitis [PDF]

open access: yesGraefe's Archive for Clinical and Experimental Ophthalmology, 2004
To compare in-season eotaxin-1 levels in tears of patients suffering from seasonal allergic conjunctivitis (SAC) with (1) tears of normal subjects and (2) tears of SAC patients out of season.Tears of 11 SAC patients and six control volunteers were collected during the pollen season.
Eperon, S.   +5 more
openaire   +3 more sources

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND:Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma.
Gustavo Nino   +10 more
doaj   +1 more source

EFFECTS OF DIET ON CCL11 EXPRESSION AND AGING OF LUNGS AND TESTES OF MICE

open access: yesThe Journal of Animal and Plant Sciences, 2022
Aging is a complex phenomenon symbolized by dynamic loss of tissue homeostasis with diminished cellular function. Along with genetic factors, many epigenetic factors as such lifestyle of an individual also affects aging. The aim of this study was to check the effect of different food habits in the process of aging using an aging biomarker CCL11.
S Rehman   +4 more
openaire   +1 more source

IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells

open access: yesCellular Physiology and Biochemistry, 2016
Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions.
Yoshitaka Hosokawa   +4 more
doaj   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells [PDF]

open access: yesAllergy, 2008
Background:  Airway smooth muscle hyperplasia is a feature of asthma, and increases with disease severity. CCR3‐mediated recruitment of airway smooth muscle progenitors towards the airway smooth muscle bundle has been proposed as one possible mechanism involved in airway smooth muscle hyperplasia.
Saunders, R   +8 more
openaire   +3 more sources

Effects of intense pulsed light treatment on tear cytokines and clinical outcomes in meibomian gland dysfunction.

open access: yesPLoS ONE, 2021
Meibomian gland dysfunction (MGD) has become a prevalent ocular surface disorder. Its pathogenesis is regarded as a self-perpetuating inflammatory vicious circle.
Qian Li   +6 more
doaj   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

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