Results 51 to 60 of about 11,477 (173)
CD14+CD33+ myeloid cell-CCL11-eosinophil signature in ulcerative colitis [PDF]
Journal of Leukocyte Biology, 2013 ABSTRACTThis study tested the hypothesis that eotaxins (CCL11, CCL24, and CCL26) and IL-5 contribute to eosinophil recruitment to the intestine in UC and that intestinal macrophages are important producers of CCL11 in this disease. Peripheral blood and rectal biopsy samples were obtained from patients with active (n=18) and quiescent UC (n=9), and ...
Maria, Lampinen +4 more
openaire +2 more sources
Scientific Reports, 2023 Chemokines are chemotactic cytokines that can cause directed migration of leukocytes. The aim of this study was to examine differences in single nucleotide polymorphisms (SNP) of chemokine in AITD patients compared to normal controls.
Chungwoo Shin +4 more
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background To systematically evaluate the local biomarkers correlated with olfactory dysfunction (OD) in chronic rhinosinusitis (CRS). Methods A systematic review was conducted in CINAHL, Cochrane Library, PubMed, and Scopus from inception to July 2025.
David Kayekjian +4 more
wiley +1 more source
CCL11 (Eotaxin) Induces CCR3-Dependent Smooth Muscle Cell Migration [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2004 Objective— CCL11 (Eotaxin) is a potent eosinophil chemoattractant that is abundant in atheromatous plaques. The major receptor for CCL11 is CCR3, which is found on leukocytes and on some nonleukocytic cells. We sought to determine whether vascular smooth muscle cells (SMCs) possessed functional CCR3.
Ravindra B, Kodali +6 more
openaire +2 more sources
Arthritis &Rheumatology, EarlyView.Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó +84 more
wiley +1 more source
Association of inflammatory gene polymorphisms with ischemic stroke in a Chinese Han population
Journal of Neuroinflammation, 2012 Background Inflammatory mechanisms are important in stroke risk, and genetic variations in components of the inflammatory response have been implicated as risk factors for stroke.
Zhao Nan +11 more
doaj +1 more source
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source
Serum C-C motif ligand 11/Eotaxin-1 may serve as a candidate biomarker for postmenopausal osteoporosis [PDF]
Journal of Medical Biochemistry, 2019 Background: The chemokine C-C motif ligand 11, also known as eotaxin-1, has been identified as a novel mediator of inflammatory bone resorption. However, little is known regarding a potential role for CCL11/Eotaxin-1 in postmenopausal osteoporosis ...
Wang Wen +6 more
doaj
Frontiers in Neurology, 2018 BackgroundA prominent pathological feature of neuromyelitis optica spectrum disorders (NMOSD) is markedly greater eosinophilic infiltration than that seen in other demyelinating diseases, like multiple sclerosis (MS).
Yanping Tong +10 more
doaj +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Clinical translation of novel therapies can be hindered by heterogeneity‐driven sample size inflation in late‐stage trials. In acetaminophen‐induced liver injury (APAP DILI), many patients recover spontaneously, diluting investigational drug efficacy signals.
Chris Humphries +8 more
wiley +1 more source