Results 41 to 50 of about 12,716 (189)

CCL11 promotes HCC recurrence after liver surgery via activating immunosuppressive macrophages

, 2022
Background Surgical stress and chronic inflammation seriously trigger chemokine-mediated dysregulations of the hepatic environment, resulting in tumor progression and recurrence after liver surgery.
Yeung, Oscar Wai Ho, Pang, Li, Ng, Tak Pan, Man, Kwan, Qiu, Wenqi, Wang, Jiaqi   +5 more
core   +1 more source

Cytokine and Chemokine mRNA Expressions after Mycobacterium tuberculosis-Specific Antigen Stimulation in Whole Blood from Hemodialysis Patients with Latent Tuberculosis Infection

Diagnostics, 2021
There have been few reports on the kinetics of hemodialyzed (HD) patients’ immune responses in latent tuberculosis infection (LTBI). Therefore, in the present study, messenger ribonucleic acid (mRNA) expression levels of nine immune markers were analyzed
Ji Young Park, Sung-Bae Park, Heechul Park, Jungho Kim, Ye Na Kim, Sunghyun Kim   +5 more
doaj   +1 more source

Eotaxin-1 (CCL11) up-regulation in tears during seasonal allergic conjunctivitis [PDF]

Graefe's Archive for Clinical and Experimental Ophthalmology, 2004
To compare in-season eotaxin-1 levels in tears of patients suffering from seasonal allergic conjunctivitis (SAC) with (1) tears of normal subjects and (2) tears of SAC patients out of season.Tears of 11 SAC patients and six control volunteers were collected during the pollen season.
Eperon, S., Sauty, A., Lanz, R., Leimgruber, A., Lurati, F., Guex-Crosier, Y.   +5 more
openaire   +3 more sources

Directional secretory response of double stranded RNA-induced thymic stromal lymphopoetin (TSLP) and CCL11/eotaxin-1 in human asthmatic airways. [PDF]

PLoS ONE, 2014
BACKGROUND:Thymic stromal lymphoproetin (TSLP) is a cytokine secreted by the airway epithelium in response to respiratory viruses and it is known to promote allergic Th2 responses in asthma.
Gustavo Nino, Shehlanoor Huseni, Geovanny F Perez, Krishna Pancham, Humaira Mubeen, Aleeza Abbasi, Justin Wang, Stephen Eng, Anamaris M Colberg-Poley, Dinesh K Pillai, Mary C Rose   +10 more
doaj   +1 more source

EFFECTS OF DIET ON CCL11 EXPRESSION AND AGING OF LUNGS AND TESTES OF MICE

The Journal of Animal and Plant Sciences, 2022
Aging is a complex phenomenon symbolized by dynamic loss of tissue homeostasis with diminished cellular function. Along with genetic factors, many epigenetic factors as such lifestyle of an individual also affects aging. The aim of this study was to check the effect of different food habits in the process of aging using an aging biomarker CCL11.
S Rehman, S Nadeem, H Zaman, M.S. Aslam, Z Abbas   +4 more
openaire   +1 more source

The airway smooth muscle CCR3/CCL11 axis is inhibited by mast cells [PDF]

Allergy, 2008
Background:  Airway smooth muscle hyperplasia is a feature of asthma, and increases with disease severity. CCR3‐mediated recruitment of airway smooth muscle progenitors towards the airway smooth muscle bundle has been proposed as one possible mechanism involved in airway smooth muscle hyperplasia.
Saunders, R, Sutcliffe, A, Woodman, L, Kaur, D, Siddiqui, S, Okayama, Y, Wardlaw, A, Bradding, P, Brightling, C   +8 more
openaire   +3 more sources

S100A14 in Tumor‐Derived EVs Targets PIAS3 to Reprogram Astrocytes and Induce Immunosuppressive Microenvironment Promoting Brain Metastasis and Germacrone Reversal Effect

Advanced Science, EarlyView.
This study identifies S100A14 in tumor‐derived exosomes as a key driver of brain metastasis. S100A14 targets PIAS3 in astrocytes, activating STAT3 signaling and promoting immunosuppressive MDSCs recruitment via chemokine secretion. Germacrone, a natural compound, binds S100A14 to disrupt this axis, effectively inhibiting brain metastasis with low ...
Qian Feng, Xia Yang, Lin An, Xue‐Yu Wang, Ming‐Rui Wang, Zhuo‐Hong Cai, Cai‐Jun Xie, Li‐Jun Qiao, You‐Bi Shen, Xi‐Min Liang, Rong Zhang, Cai‐Yan Wang, Zhong‐Qiu Liu, Rong‐Rong Zhang   +13 more
wiley   +1 more source

The chemokines CCL11, CCL20, CCL21, and CCL24 are preferentially expressed in polarized human secondary lymphoid follicles

, 2004
Chemokines regulate cellular trafficking to and from lymphoid follicles. Here, the distribution pattern of four CCL chemokines is defined by in situ hybridization in human lymphoid follicles from tonsils and lymph nodes (LNs) of newborns and adults ...
Müller, Christoph, Buri, Caroline, Kappeler, Andreas, Gutersohn, Andreas, Hauser, Chantal   +4 more
core   +1 more source

The allergy-associated chemokine receptors CCR3 and CCR5 can be inactivated by the modified chemokine NNY-CCL11

, 2022
S.17-24Background: CC chemokine ligand 11 (CCL11) is the outstanding member of all described CC chemokine receptor 3 (CCR3) ligands and is shown to be selective for this receptor. However, it also activates CCR5 but only in the micromolar range.
Rieder, S., Forssmann, W.-G., Elsner, J., Manns, J., Escher, S., Forssmann, U., Eilers, B.   +6 more
core   +1 more source

Effects of intense pulsed light treatment on tear cytokines and clinical outcomes in meibomian gland dysfunction.

PLoS ONE, 2021
Meibomian gland dysfunction (MGD) has become a prevalent ocular surface disorder. Its pathogenesis is regarded as a self-perpetuating inflammatory vicious circle.
Qian Li, Junxiu Liu, Cheng Liu, Junfeng Piao, Wei Yang, Ningyu An, Jinyan Zhu   +6 more
doaj   +1 more source