CCL11 levels in drug-naive bipolar patients: The role of sex and smoking status
Background: It has been reported that patients with bipolar disorder (BD) present changes in peripheral levels of the inflammatory cytokine CCL11, particularly at latestages.
Bianca Wollenhaupt-Aguiar +2 more
exaly +3 more sources
Emerging Roles of C-C Motif Ligand 11 (CCL11) in Cancers and Liver Diseases: Mechanisms and Therapeutic Implications [PDF]
C-C motif ligand 11 (CCL11) is a multifunctional chemokine that regulates immunity, angiogenesis, and tissue remodeling. In addition to its allergic inflammation role, CCL11 exhibits context-dependent dual functions in relation to cancer progression.
Kwan Man, Kevin Tak-Pan Ng, Man Kwan
exaly +3 more sources
IL-4 Modulates CCL11 and CCL20 Productions from IL-1β-Stimulated Human Periodontal Ligament Cells [PDF]
Background/Aims: IL-4 is a multifunctional cytokine that is related with the pathological conditions of periodontal disease. However, it is uncertain whether IL-4 could control T cells migration in periodontal lesions.
Yoshitaka Hosokawa +4 more
doaj +4 more sources
CCL11 (Eotaxin) Promotes the Advancement of Aging-Related Cardiovascular Diseases
Aging-related diseases, such as cardiovascular diseases (CVDs), neurodegeneration, cancer, etc., have become important factors that threaten the lifespans of older individuals. A chronic inflammatory response is closely related to aging-related diseases.
Tanwei Zhang +4 more
doaj +3 more sources
Brexanolone infusion produces sustained anti-inflammatory and neurotrophic effects in patients with postpartum depression that predict symptom improvement [PDF]
Postpartum depression (PPD) is linked to neuroimmune dysregulation. Brexanolone, an intravenous formulation of the neurosteroid allopregnanolone and the first FDA-approved treatment for PPD, produces rapid and sustained antidepressant effects.
Irina Balan +7 more
doaj +2 more sources
Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis
Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI +6 more
doaj +4 more sources
Qifuyin against CCL11-Induced cognitive impairment by inhibiting microglial senescence via CCR3 signaling [PDF]
Background The chemokine CCL11 is negatively correlated with cognitive function and is able to cause dysfunctions of synaptic plasticity. This research investigate whether CCL11 induce microglia senescence to damage synaptic plasticity and the protective
Sheng Tian +7 more
doaj +2 more sources
Introduction. Eosinophils play an important role in development ofallergic diseases. Recent studies indicate their many relevant functionsin the development of allergic inflammation related to both an effectorand immunomodulatory role. The recognition of
Agnieszka Nawrocka +3 more
doaj +1 more source
Peripheral vascular disease (PVD) is an emerging public health burden with a high rate of disability and mortality. Gasdermin D (GSDMD) has been reported to exert pyroptosis and play a critical role in the pathophysiology of many cardiovascular diseases.
Yiwen Wang +11 more
doaj +2 more sources
Evolution of CCL11: genetic characterization in lagomorphs and evidence of positive and purifying selection in mammals [PDF]
The interactions between chemokines and their receptors are crucial for differentiation and activation of inflammatory cells. CC chemokine ligand 11 (CCL11) binds to CCR3 and to CCR5 that in leporids underwent gene conversion with CCR2. Here, we genetically characterized CCL11 in lagomorphs (leporids and pikas).
Fabiana Neves +2 more
exaly +3 more sources

