Results 251 to 260 of about 100,458 (303)

Chemokine-defined macrophage niches establish spatial organization of tumor immunity. [PDF]

open access: yesNat Immunol
Ghosh S   +8 more
europepmc   +1 more source

The long noncoding RNA <i>lnc-FAM164A1</i>-ACLY axis promotes pro-inflammatory responses in human primary macrophages: a systems approach. [PDF]

open access: yesFront Immunol
Wang JG   +18 more
europepmc   +1 more source

Stimulation of CCL2 (MCP-1) and CCL2 mRNA by substance P in LAD2 human mast cells

open access: yesTranslational Research, 2009
Chemokines are cytokines with chemotactic properties on inflammatory cells and other cell types. Chemokine (C-C motif) ligand 2 (CCL2), which is also called monocyte chemotactic protein 1 (MCP-1), is a potent chemotactic molecule that attracts lymphocytes, monocytes, mast cells, and memory T cells, but not neutrophils.
Castellani ML   +12 more
openaire   +7 more sources
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CCL2 (monocyte chemoattractant protein-1) and cancer

Seminars in Cancer Biology, 2004
Genetic analyses of cancer in humans indicate that chemokines and their receptors are unlikely to play direct roles in pathogenesis. However, these molecules have pleiotropic effects that impact on cancer pathobiology in animal models, and there is evidence that they may do the same in humans. Given their protean properties, chemokines could have tumor-
Barrett J Rollins
exaly   +3 more sources

CCL2 in the Tumor Microenvironment

2021
The C-C motif chemokine ligand 2 (CCL2) is a crucial mediator of immune cell recruitment during microbial infections and tissue damage. CCL2 is also frequently overexpressed in cancer cells and other cells in the tumor microenvironment, and a large body of evidence indicates that high CCL2 levels are associated with more aggressive malignancies, a ...
O'Connor, T., Heikenwälder, M.
openaire   +3 more sources

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