Results 101 to 110 of about 63,484 (304)

The Effect of Leunca Fruit (Solanum nigrum Linn) Infusion in Inhibiting the Increase of Serum Glutamate Pyruvate Transaminase Level in CCL4 Induced Hepatitis Wistar Rats

Althea Medical Journal, 2019
Background: Hepatitis may cause liver cell damage due to the oxidation processes and can be inhibited by antioxidant components. Antioxidant acts as hepatoprotector by slowing down the oxidation process.
Kuswinarti Kuswinarti, Syifa Karmani, Coriejati Rita   +2 more
doaj   +1 more source

Alveolar bone resorption via the CCL4 and CCL7-CCR5 axis in a mouse model of periodontitis [PDF]

明海大学博士（歯学 ...
ヤマネ, ユウスケ, 山根, 佑介, YAMANE, Yusuke   +2 more
core  

Anti-apoptotic and antioxidant effect of leptin on CCl4-induced acute liver injury in rats

, 2011
The aim of this study is to investigate the effect of leptin in rats on carbon tetrachloride (CCl4) induced acute liver damage using immunohistochemical methods for apoptosis and biochemical parameters.
Nilüfer Erkasap, Canan Baydemir, Serbetci, Kerim, Baydemir, Canan, Serdar Erkasap, Tülay Köken, Koken, Tulay, Onur Uysal, Erkasap, Nilufer, Erkasap, Serdar, Kerim Şerbetçi, Uysal, Onur   +11 more
core   +1 more source

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

Advanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan, Andi Ma, Yiqiong Zhang, Minghao Zhang, Yifeng Lin, Xiaoling Zhang, Hongjun Li, Weidong Han   +7 more
wiley   +1 more source

scH16S‐Seq Maps Klebsiella pneumoniae‐Associated Myeloid States and Reveals a CD38–NAD Immunometabolic Axis That Impairs Lysosomal Acidification in Sepsis

Advanced Science, EarlyView.
Single‐cell host–bacterial 16S co‐sequencing (scH16S‐seq) integrates cell‐associated bacterial 16S‐derived signals with host transcriptomes to resolve bacterial signal‐enriched myeloid states in Klebsiella pneumoniae sepsis. Complementary pharmacological and genetic analyses define a CD38–NAD immunometabolic axis connecting mitochondrial bioenergetic ...
Yangguang Li, Yilong Yu, Fang Qin, Shenxing Li, Xuanheng Li, Peizhao Liu, Juanhan Liu, Haiqing Liu, Songqi Jing, Jianghao Zou, Sicheng Li, Jiayang Li, Tao Zheng, Yun Zhao, Jianan Ren, Xiuwen Wu   +15 more
wiley   +1 more source

Crocin (active constituent of saffron) improves CCl4-induced liver damage by modulating oxidative stress in rats

, 2019
Background: CCl4 is a widely used xenobiotic for the purpose of causing liver damage in experimental studies. In this study, we aimed to reveal the effects of crocin on liver injury caused by CCl4 via free radical scavenging properties.
Gul, Semir, Gul, Mehmet, Cosgun, Binnaz Elif, Erdemli, Mehmet Erman, Bag, Harika Gozukara, Erdemli, Zeynep, Altinoz, Eyup   +6 more
core   +3 more sources

The liver‐brain axis: A multidimensional regulatory network implicated in Alzheimer's disease pathogenesis and clinical implications

Animal Models and Experimental Medicine, EarlyView.
Schematic diagram of the core pathways of the liver‐brain axis in regulating AD. The liver regulates cerebral Aβ deposition, tau phosphorylation, and neuroinflammation through pathways such as metabolic detoxification (urea cycle, ketone body metabolism, glutathione antioxidant system), molecular secretion (APOE, CRP, FGF21, IGF‐1), and Aβ clearance ...
Ning Zhang, Wei Chen, Meng Wang
wiley   +1 more source

Evaluation of Hepatoprotective Activity of the Crude Extract and Solvent Fractions of Clutia abyssinica (Euphorbiaceae) Leaf Against CCl4-Induced Hepatotoxicity in Mice

Journal of Experimental Pharmacology, 2020
Birhanu Geta Meharie, Gedefaw Getnet Amare, Yaschilal Muche Belayneh Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, EthiopiaCorrespondence: Birhanu Geta MeharieDepartment of Pharmacy, College of Medicine and ...
Meharie BG, Amare GG, Belayneh YM
doaj  

Pemberian Ekstrak Chlorella vulgaris terhadap Aktivitas Sgot Tikus Putih (Rattus norvegicus) yang diinduksi CCl4 [PDF]

, 2017
Chlorella vulgaris adalah mikroalga hijau, uniseluler berbentuk bulat atau elips berdiameter 2-10 µm kaya akan klorofil dan zat-zat yang berpotensi sebagai antioksidan seperti β-karoten, mineral, dan vitamin.
UTAMI, Yovi
core  

Effects of saikosaponin-d on enhanced CCl4-hepatotoxicity by phenobarbitone

, 1985
The effects of saikosaponin-d extracted from the roots of Bupleurum falcatum L. on increased toxicity of CCl4 and increased activities of microsomal enzymes induced by phenobarbitone have been examined.
Hiroyoshi Konishi, Hiroko Abe, Shizuo Odashima, Machiko Orita, Shigeru Arichi   +4 more
core   +1 more source