Results 51 to 60 of about 59,717 (249)

Ccl5 Mediates Proper Wiring of Feedforward and Lateral Inhibition Pathways in the Inner Retina

open access: yesFrontiers in Neuroscience, 2018
The β-chemokine Ccl5 and its receptors are constitutively expressed in neurons of the murine inner retina. Here, we examined the functional and structural significance of this constitutive Ccl5 signaling on retinal development.
D’Anne S. Duncan   +10 more
doaj   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

Near‐Infrared Light‐Activated Polydopamine Nanoparticles Conjugated With Transferrin Peptides for Enhanced Brain Accumulation

open access: yesAdvanced Healthcare Materials, EarlyView.
This study demonstrates that Tf‐PDA NPs combine a receptor‐mediated targeting with mild photothermal activation to enhance nanoparticle accumulation in the brain. NIR‐activated Tf‐PDA NPs increase BBB permeability to NPs in vitro and in vivo without inducing cytotoxicity or adverse immune responses.
Rafaela Ferrão   +5 more
wiley   +1 more source

CCL5 expression in OTSCC patient samples.

open access: yes, 2013
CCL5 is mainly expressed by inflammatory cells in TME and some cancer cells in patient samples as shown by immunostaining with Pab CCL5, but only sparse CAFs are positive for CCL5 (A, B).
Marilena Vered (474920)   +14 more
core   +1 more source

Research Trends and Regulation of CCL5 in Prostate Cancer

open access: yes, 2021
Prostate cancer (PCa) is considered as the most common cancer of urologic neoplasms, and its development and prognosis are associated with many factors.
Xiang, Songtao   +9 more
core   +1 more source

Dual Role of Tamoxifen in Enhancing STING and CEACAM1 Expression to Prime a Favorable Tumor Microenvironment for Anti‐TIM3 Immunotherapy

open access: yesAdvanced Science, EarlyView.
Anti‐PD‐1/PD‐L1 blockade has revolutionized cancer immunotherapy, but is ineffective against endocrine‐treated (i.e., Tamoxifen), relapsed ER+ breast cancer (BC) patients. This study provides insight into the sub‐optimal response of ER+BCs to anti‐PD‐1/PD‐L1 blockade – highlighting the induction of STING and the CEACAM1/TIM3 axis after chronic ...
Marvin Angelo E Aberin   +20 more
wiley   +1 more source

T-Lymphocyte Gene-Regulated CCL5 and Its Association with Extrahepatic Metastasis in Hepatocellular Carcinoma

open access: yes, 2023
Guoping Dong,1,2 Fangying Fan,1,2 Yao He,3 Yanchun Luo,1 Jie Yu,1,2 Ping Liang1,2 1Department of Interventional Ultrasound, Fifth Medical Center of Chinese PLA General Hospital, Beijing, 100853, People’s Republic of China; 2Chinese PLA Medical School ...
Fan F   +5 more
core  

Molecular pathways involved in metabolic control of CCL5 in adipocytes [PDF]

open access: yes, 2014
2012 - 2013Obesity is a chronic disorder characterized by a tonic low-grade activation of the innate immune system that affects steady-state measures of metabolic homeostasis over time.
Passaretti, Federica
core   +1 more source

Study on expression levels of chemokine CCL5 in peripheral blood of patients with alopecia areata

open access: yesPifu-xingbing zhenliaoxue zazhi
[Objective] To explore the role of C-C motif chemokine ligand 5(CCL5) in the pathogenesis of alopecia areata, by detecting the expression levels of C-C motif chemokine ligand 5 (CCL5) in peripheral blood mononuclear cells (PBMCs) and serum of patients ...
TAN Yudan   +5 more
doaj   +1 more source

Tumor bud-derived CCL5 recruits fibroblasts and promotes colorectal cancer progression via CCR5-SLC25A24 signaling

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
Background Tumor budding is included in the routine diagnosis of colorectal cancer (CRC) and is considered a tumor prognostic factor independent of TNM staging.
Ling-Fang Gao   +7 more
doaj   +1 more source

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