Results 31 to 40 of about 59,717 (249)

CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury

Redox Biology, 2021
Traumatic brain injury (TBI) is a prevalent head injury worldwide which increases the risk of neurodegenerative diseases. Increased reactive oxygen species (ROS) and inflammatory chemokines after TBI induces secondary effects which damage neurons ...
Man-Hau Ho, Chia-Hung Yen, Tsung-Hsun Hsieh, Tzu-Jen Kao, Jing-Yuan Chiu, Yung-Hsiao Chiang, Barry J. Hoffer, Wen-Chang Chang, Szu-Yi Chou   +8 more
doaj   +1 more source

Functional role of CCL5/RANTES for HCC progression during chronic liver disease [PDF]

, 2016
Background & Aims: During liver inflammation, triggering fibrogenesis and carcinogenesis immune cells play a pivotal role. In the present study we investigated the role of CCL5 in human and in murine models of chronic liver inflammation leading to ...
Cubero, Francisco Javier, Reissing, Johanna, Mohs, Antje, Proudfoot, Amanda, Youssef, Sameh A., de Bruin, Alain, Youssef, Sameh A, Cubero Palero, Francisco Javier, Wolfgang Zimmermann, Henning, Javier Cubero, Francisco, Zimmermann, Henning Wolfgang, Trautwein, Christian, Kuttkat, Nadine, Sonntag, Roland   +13 more
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What a dog transmissible tumor can teach us about cancer regression

Molecular & Cellular Oncology, 2018
The canine transmissible venereal tumor (CTVT) is one of the few clonally transmissible cancers in nature and the only one that fully regresses following treatment with vincristine.
Ariberto Fassati
doaj   +1 more source

Network Pharmacology and Inflammatory Microenvironment Strategy Approach to Finding the Potential Target of Siraitia grosvenorii (Luo Han Guo) for Glioblastoma

Frontiers in Genetics, 2021
Background: Glioblastoma (GBM) is the most common and aggressive primary intracranial tumor of the central nervous system, and the prognosis of GBM remains a challenge using the standard methods of treatment—TMZ, radiation, and surgical resection ...
Juan Li, De Bi, Xin Zhang, Yunpeng Cao, Kun Lv, Kun Lv, Lan Jiang, Lan Jiang   +7 more
doaj   +1 more source

Chemokine Ligand 5 to Predict Optimal Cytoreduction in Ovarian Cancer

International Journal of General Medicine, 2020
Yudi Mulyana Hidayat,1 Munizar,1 Ali Budi Harsono,1 Gatot Nyarumenteng Adhipurnawan Winarno,1 Hasanuddin,2 Siti Salima1 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Obstetrics ...
Hidayat YM, Munizar, Harsono AB, Winarno GNA, Hasanuddin, Salima S   +5 more
doaj  

CCL5 mediates breast cancer metastasis and prognosis through CCR5/Treg cells

Frontiers in Oncology, 2022
Background and aimsCCL5 is considered to contribute to the biological function of a variety of cancer types, but its specific mechanism is still unclear.
Juanjuan Qiu, Juanjuan Qiu, Li Xu, Xiaohong Zeng, Hao Wu, Hao Wu, Faqing Liang, Qing Lv, Zhenggui Du   +8 more
doaj   +1 more source

CCL5/RANTES is important for inducing osteogenesis of human mesenchymal stem cells and is regulated by dexamethasone

, 2017
In this study, we examine the effect of chemokine (C-C motif) ligand 5 (CCL5)/Regulated on Activation Normal T cell Expressed and Secreted (RANTES), a pro-inflammatory cytokine on osteogenic differentiation of human mesenchymal stem cells (hMSCs).
Liu, Yu-Chuan;Kao, Yu-Ting;Huang, Wei-Kai;Lin, Kun-Yi;Wu, Shinn-Chih;Hsu, Shu-Ching;Schuyler, Scott C.;Li, Long-Yuan;Lu, Frank Leigh;Lu, Jean, 呂立   +1 more
core   +1 more source

CCL5’s Role in Periodontal Disease: A Narrative Review

, 2023
Persistent host inflammatory and immune responses to biofilm play a critical role in the mechanisms that govern soft and hard tissue destruction in periodontal disease.
Diana Cenariu, Katarzyna Barczak, Ryta Łagocka, Agnieszka Droździk, Willi Andrei Uriciuc, Irena Baranowska-Bosiacka, Mateusz Bosiacki   +6 more
core   +1 more source

The Expression and Function of CCL5 in Early Atherosclerosis [PDF]

, 2017
Atherosclerosis is a chronic cardiovascular disease initiated by the accumulation of lipid-loaded macrophages within the artery wall. Chemokines can have several potential functions in atherosclerosis.
Tai, Kelly
core   +2 more sources

CCL5 (RANTES)-Induced Activation of Spinal Astrocytes can contribute to Neuroinflammation and the Maintenance of Chronic Inflammatory Pain.

, 2022
This thesis research is based on the work initiated by the previous findings of our laboratory (Gajtkó A. et al. 2020) which showed that the chemokine CCL5 is overexpressed in the spinal dorsal horn at the peak of CFA-induced inflammatory pain.
Dabberha, Ali
core