Results 31 to 40 of about 50,982 (245)

CCR5 status and metastatic progression in colorectal cancer

open access: yesOncoImmunology, 2019
Multiple reports have highlighted the importance of the local immunological cellular composition (i.e. the density of effector T cells and macrophage polarization state) in predicting clinical outcome in advanced metastatic stage of colorectal cancer ...
Meggy Suarez-Carmona   +22 more
doaj   +1 more source

CCL5 might be a prognostic biomarker and associated with immuno-therapeutic efficacy in cancers: A pan-cancer analysis

open access: yesHeliyon, 2023
Purpose: Chemokine ligand 5 (CCL5), a vital member of the CC chemokine family, plays diverse roles in tumorigenesis, metastasis, and prognosis in various human tumors.
Yanchun Huang   +7 more
doaj   +1 more source

Regulation of CCL5 expression in smooth muscle cells following arterial injury. [PDF]

open access: yesPLoS ONE, 2012
Chemokines play a crucial role in inflammation and in the pathophysiology of atherosclerosis by recruiting inflammatory immune cells to the endothelium. Chemokine CCL5 has been shown to be involved in atherosclerosis progression. However, little is known
Huan Liu   +6 more
doaj   +1 more source

Research Trends and Regulation of CCL5 in Prostate Cancer

open access: yesOncoTargets and Therapy, 2021
Prostate cancer (PCa) is considered as the most common cancer of urologic neoplasms, and its development and prognosis are associated with many factors. Chemokine receptor signaling combine with advances in advanced clinicopathological characteristics have provided new insights into the molecular landscape of prostate cancer.
Renlun Huang   +4 more
openaire   +5 more sources

CCL5’s Role in Periodontal Disease: A Narrative Review

open access: yesInternational Journal of Molecular Sciences, 2023
Persistent host inflammatory and immune responses to biofilm play a critical role in the mechanisms that govern soft and hard tissue destruction in periodontal disease. Among the less explored facets of these mechanisms are chemokines, including CCL5 (C-C motif chemokine ligand 5), also known as RANTES (regulated on activation, normal T cell expressed ...
Katarzyna Barczak   +6 more
openaire   +2 more sources

A CCL5 Haplotype Is Associated with Low Seropositivity Rate of HCV Infection in People Who Inject Drugs. [PDF]

open access: yesPLoS ONE, 2016
The role of CC chemokine receptor 5 (CCR5) and its ligand CCL5 on the pathogenesis of HIV infection has been well studied but not for HCV infection. Here, we investigated whether CCL5 haplotypes influence HIV and HCV seropositivity among 373 Caucasian ...
Kristi Huik   +13 more
doaj   +1 more source

CCL5 via GPX1 activation protects hippocampal memory function after mild traumatic brain injury

open access: yesRedox Biology, 2021
Traumatic brain injury (TBI) is a prevalent head injury worldwide which increases the risk of neurodegenerative diseases. Increased reactive oxygen species (ROS) and inflammatory chemokines after TBI induces secondary effects which damage neurons ...
Man-Hau Ho   +8 more
doaj   +1 more source

Network Pharmacology and Inflammatory Microenvironment Strategy Approach to Finding the Potential Target of Siraitia grosvenorii (Luo Han Guo) for Glioblastoma

open access: yesFrontiers in Genetics, 2021
Background: Glioblastoma (GBM) is the most common and aggressive primary intracranial tumor of the central nervous system, and the prognosis of GBM remains a challenge using the standard methods of treatment—TMZ, radiation, and surgical resection ...
Juan Li   +7 more
doaj   +1 more source

What a dog transmissible tumor can teach us about cancer regression

open access: yesMolecular & Cellular Oncology, 2018
The canine transmissible venereal tumor (CTVT) is one of the few clonally transmissible cancers in nature and the only one that fully regresses following treatment with vincristine.
Ariberto Fassati
doaj   +1 more source

Chemokine Ligand 5 to Predict Optimal Cytoreduction in Ovarian Cancer

open access: yesInternational Journal of General Medicine, 2020
Yudi Mulyana Hidayat,1 Munizar,1 Ali Budi Harsono,1 Gatot Nyarumenteng Adhipurnawan Winarno,1 Hasanuddin,2 Siti Salima1 1Department of Obstetrics and Gynecology, Faculty of Medicine, Universitas Padjadjaran, Bandung, Indonesia; 2Department of Obstetrics ...
Hidayat YM   +5 more
doaj  

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