Microarray Analysis Reveals Increased Transcriptional Repression and Reduced Metabolic Activity but Not Major Changes in the Core Apoptotic Machinery during Maturation of Sympathetic Neurons [PDF]
, 2016 Postnatal maturation of the neurons whose main phenotype and basic synaptic contacts are already established includes neuronal growth, refinement of synaptic contacts, final steps of differentiation, programmed cell death period (PCD) etc.
Jaan ePalgi +4 more
core +1 more source
Simulations of tropospheric joint distributions in the UW θ‐σ model and CCM2 [PDF]
Geophysical Research Letters, 1997 Results are presented for experiments which examine the ability of the University of Wisconsin (UW) hybrid isentropic‐sigma (θ‐σ) and sigma (σ) coordinate models and the NCAR Community Climate Model 2 (CCM2) to transport and conserve the joint distributions of potential temperature (θ) or equivalent potential temperature (θe) and a source‐free inert ...
Tom H. Zapotocny +6 more
openaire +1 more source
Quality Assessment of Hydrogeomorphological Features Derived from Digital Terrain Models [PDF]
, 2008 Digital terrain models (DTM) provide a model for representing the continuous earth elevation surface that can contain errors introduced by the main phases of generation and modelling. Uncertainty of the model is rarely considered by users.
POGGIO Laura, SOILLE Pierre
core
The atmospheric ‘cold blob’ over Fennoscandia from October 2023 to January 2024
Weather, Volume 80, Issue 1, Page 10-16, January 2025.Between October 2023 and January 2024, a persistent region of cold air prevailed over Fennoscandia. While these 4 months were the warmest on record globally, they were all colder than normal in Fennoscandia, in stark contrast to the surrounding mid‐ and high latitudes of the Northern Hemisphere.
Mika Rantanen +3 more
wiley +1 more source
Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease [PDF]
, 2016 Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we observed higher expression of Yap1/Ctgf axis in dysplastic nodules and HCC chemically-induced in F344 rats, genetically susceptible to hepatocarcinogenesis ...
Avila, Matias A. +13 more
core +2 more sources
Inherited cavernous malformations of the central nervous system: clinical and genetic features in 19 Swiss families [PDF]
, 2018 Cavernous malformations (CCMs) are benign, well-circumscribed, and mulberry-like vascular malformations that may be found in the central nervous system in up to 0.5% of the population. Cavernous malformations can be sporadic or inherited.
Andermann, F. +11 more
core
Supercontinuum pulse shaping in the few-cycle regime [PDF]
, 2013 The synthesis of nearly arbitrary supercontinuum pulse forms is demonstrated with sub-pulse structures that maintain a temporal resolution in the few-cycle regime.
Gause, Oliver +3 more
core +1 more source
Immunity, Inflammation and Disease, Volume 12, Issue 9, September 2024.The present study proposed a series of DNA damage response (DDR) DNA methylation‐based subtypes of melanomas with distinct prognosis, transcriptional function profiles of DDR and immunity, and immunotherapy response. Those novel epigenetic DDR classification schemes for melanomas not only provide ideal models for illustrating the interrelationship ...
Min Wang +5 more
wiley +1 more source
Impact of absorbing aerosols on the simulation of climate over the Indian region in an atmospheric general circulation model [PDF]
, 2004 The impact of anthropogenic absorbing aerosols (such as soot) on the climate over the Indian region has been studied using the NCMRWF general circulation model.
A. Chakraborty +3 more
core +3 more sources
Structural and biochemical characterization of the C‐terminal region of the human RTEL1 helicase
Protein Science, Volume 33, Issue 9, September 2024.Abstract RTEL1 is an essential DNA helicase which plays an important role in various aspects of genome stability, from telomere metabolism to DNA replication, repair and recombination. RTEL1 has been implicated in a number of genetic diseases and cancer development, including glioma, breast, lung and gastrointestinal tumors. RTEL1 is a FeS helicase but,
Giuseppe Cortone +9 more
wiley +1 more source