Results 141 to 150 of about 22,512 (231)

Structural and biochemical characterization of eukaryotic mRNA decapping activators [PDF]

, 2014
In eukaryotes, mRNA turnover starts with the truncation of 3′ poly(A) tail and proceeds with either 3′-to-5′ degradation by the exosome complex or with decapping followed by 5′-to-3′ degradation by Xrn1.
Sharif, Humayun
core  

CAF1-knockout mice are more susceptive to lipopolysaccharide-induced acute lung injury

Journal of Inflammation Research, 2016
Jia-Xin Shi,1 Jia-Shu Li,1 Rong Hu,1 Xiao-Min Li,2 Hong Wang3 1Department of Respiratory Medicine, Lianyungang First People’s Hospital, Affiliated Hospital of Xuzhou Medical University, Affiliated Hospital of the Clinical Medical School of Nanjing ...
Shi JX, Li JS, Hu R, Li XM, Wang H
doaj  

RNA-binding protein Roq modulates the Drosophila STING antiviral immune response

Cell Investigation
The STING (stimulator of interferon genes) signaling pathway plays a pivotal role in the immune defense against viral infections in a wide range of vertebrates and invertebrates. However, the regulatory picture of this pathway is still incomplete. Herein,
Xianrui Zheng, Yiheng Jin, Chuchu Zhang, Yangyang Zhu, Huimin Guo, Renjie Duan, Yihua Xiao, Baoyi Hu, Yulong Yang, Erwen Ding, Weini Li, Muhammad Abdul Rehman Saeed, Qingshuang Cai, Shanming Ji   +13 more
doaj   +1 more source

CCR4-NOT Transcription Complex Subunit 3 [PDF]

, 2020
openaire   +1 more source

Ένζυμα μεταβολισμού RNA ως μοριακοί δείκτες καρκίνου [PDF]

, 2011
Τοτόμη, Αθηνά Γ.
core   +1 more source

Composition and function of Ccr4-Not protein complexes

, 2010
Ccr4-Not protein complexes are evolutionarily conserved and have important functions in mRNA regulatory processes. Strict regulation of mRNA’s is important for cells since they form the central connection between the genetic information in the nucleus and active protein production in the cytoplasm.
openaire   +1 more source

Transcription regulation by the human Ccr4-Not proteins

, 2004
Transcription by RNA polymerase II is a highly regulated process. Multiple protein complexes are involved in the regulation of mRNA synthesis. The Ccr4-Not complex regulates transcription at a global level and, most likely, requires other proteins to associate with promoters. The complex is evolutionary conserved from yeast to human.
openaire   +1 more source

RNA-binding proteins in mouse male germline stem cells: a mammalian perspective [PDF]

, 2016

core   +1 more source

CCR4 expression defines a targetable subset of T-cell acute lymphoblastic leukemia. [PDF]

Blood Adv
Xu J, McCoy M, Martinez Z, Sussman JH, Gao D, Vincent T, Wang H, Ma C, Elghawy O, Chen GM, Yang AG, Pölönen P, Natan K, Shraim R, Newman H, Hofmann TJ, Scoma S, DiNofia AM, Hunger SP, Yang JJ, Mullighan CG, Bernt KM, Hexner EO, Grupp SA, Watanabe K, June CH, Tan K, Teachey DT, Diorio C.   +28 more
europepmc   +1 more source

CAR T cells targeting CCR4 selectively deplete human Tregs ex vivo and in vivo. [PDF]

Blood Adv
Tilsed CM, Fong KP, Shi X, Akimova T, Wang L, Noguera-Ortega E, Krouse R, Bermudez A, Singhal S, Young R, Eruslanov E, Watanabe K, Hancock WW, June CH, Albelda SM.   +14 more
europepmc   +1 more source