Results 151 to 160 of about 22,512 (231)

The CCL17-CCR4 Axis Is Critical for Mutant STAT6-Mediated Microenvironmental Remodeling and Therapeutic Resistance in Relapsed/Refractory Diffuse Large B-Cell Lymphoma. [PDF]

open access: yesCancer Immunol Res
Abraham MJ   +13 more
europepmc   +1 more source

The CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity

open access: yesThe CCR4–NOT Deadenylase Complex Maintains Adipocyte Identity
Shortening of poly(A) tails triggers mRNA degradation; hence, mRNA deadenylation regulates many biological events. In the present study, we generated mice lacking the Cnot1 gene, which encodes an essential scaffold subunit of the CCR4–NOT deadenylase complex in adipose tissues (Cnot1-AKO mice) and we examined the role of CCR4–NOT in adipocyte function.
openaire  

Integrated genetic analyses identified T-cell neoplasms other than adult T-cell leukemia/lymphoma in HTLV-1 carriers. [PDF]

open access: yesBlood Adv
Naito Y   +19 more
europepmc   +1 more source

Peripheral Blood Skin-Homing T Cells Define Immunological Endotypes in Atopic Dermatitis: A Case-Control Study in a Mexican Population. [PDF]

open access: yesHealth Sci Rep
Luis Carlos ZP   +6 more
europepmc   +1 more source

Haploinsufficiency of Cnot3 Aggravates Acid-Induced Acute Lung Injury Likely Through Transcriptional and Post-Transcriptional Upregulation of Pro-Inflammatory Genes

open access: yesJournal of Inflammation Research
Tomokazu Yamaguchi,1,2,* Ryo Ozawa,2,3,* Takafumi Minato,2 Midori Hoshizaki,4 Yutaro Kammura,1,5 Kazuma Okawara,1,6 Yousef A Khalil,1 Masafumi Nakamura,6 Ken Yamaura,5 Masayuki Fukuda,3 Yumiko Imai,4 Keiji Kuba1,2 1Department of Pharmacology ...
Yamaguchi T   +11 more
doaj  

Human pumilio proteins use fuzzy multivalent hydrophobic interactions to recruit the CCR4-NOT deadenylase complex to repress mRNAs. [PDF]

open access: yesJ Biol Chem
Dunshee EB   +12 more
europepmc   +1 more source

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