Evolution of HIV-1 coreceptor usage through interactions with distinct CCR5 and CXCR4 domains [PDF]
Zhao-hai Lu+12 more
openalex +1 more source
Inflammation and mechanical force‐induced bone remodeling
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon+6 more
wiley +1 more source
CXCR-4 Is Expressed by Primary Macrophages and Supports CCR5-Independent Infection by Dual-Tropic but Not T-Tropic Isolates of Human Immunodeficiency Virus Type 1 [PDF]
Yanjie Yi+4 more
openalex +1 more source
Host factors and early treatments to restrict paediatric HIV infection and early disease progression [PDF]
open6noA body of evidence indicates that a threshold level of the virus is required to establish systemic and persistent HIV infection in the host and that this level depends on virus-host interactions.
De Rossi, Anita+5 more
core +1 more source
Noninvasive fetal antigen genotyping: Results from a survey on the status of clinical implementation
Abstract Background and Objectives Noninvasive fetal antigen genotyping can assist the management of immunized pregnant women, and fetal RHD genotyping can be used as a screening assay to guide restricted use of Rh prophylaxis. Based on a survey, we present an overview of the implementation of noninvasive fetal antigen genotyping into clinical practice.
Frederik Banch Clausen+54 more
wiley +1 more source
Enhanced Expression, Native Purification, and Characterization of CCR5, a Principal HIV-1 Coreceptor [PDF]
Tajib A. Mirzabekov+7 more
openalex +1 more source
Chemokine Receptor Profiles as Predictors of Survival and Early Progression in Follicular Lymphoma
Abstract Objective: Classical follicular lymphoma (FL) is a heterogeneous malignancy. Early progression within 24 months (POD24) is linked to poor outcomes. However, precise risk stratification remains unclear. We aimed to explore chemokine receptor (CR) expression profiles as potential markers of disease biology and outcome in FL. Methods: We analyzed
Antonella Zupo+19 more
wiley +1 more source
HIV-1 infection through the CCR5 receptor is blocked by receptor dimerization [PDF]
Antonio J. Vila‐Coro+6 more
openalex +3 more sources
No Evidence for an Effect of the CCR5 Δ32/+ and CCR2b 64I/+ Mutations on Human Immunodeficiency Virus (HIV)‐1 Disease Progression among HIV‐1–Infected Injecting Drug Users [PDF]
Janke Schinkel+5 more
openalex +1 more source
Pre-incubation of cell-free HIV-1 group M isolates with non-nucleoside reverse transcriptase inhibitors blocks subsequent viral replication in co-cultures of dendritic cells and T cells. [PDF]
In order to study the inhibitory effect of various reverse transcriptase inhibitors (RTIs) on cell-free HIV, we adapted a recently described in vitro system, based on co-cultures of dendritic cells and resting CD4 T cells, modelling early target cells ...
Andries, Koen+8 more
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