Results 81 to 90 of about 54,562 (253)
Regulation of CCR5 expression in human placenta: insights from a study of mother-to-child transmission of HIV in Malawi. [PDF]
PLoS ONE, 2010 Human promoter polymorphisms in the chemokine co-receptor 5 gene (CCR5) have been noted for association with mother-to-child transmission of HIV (HIV MTCT) as well as reduced receptor expression in vitro, but have not been clearly associated with CCR5 ...
Bonnie R Joubert +4 more
doaj +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.A novel graphene‐based broad‐spectrum infrared (BSIR) device is developed for the noninvasive treatment of ulcerative colitis (UC). BSIR irradiation effectively alleviates colonic inflammation and accelerates mucosal recovery by inducing the systemic relocation of T lymphocytes to the spleen.
Siyu Chen +15 more
wiley +1 more source
Glycans are involved in RANTES binding to CCR5 positive as well as to CCR5 negative cells
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2001 We show that cell surface glycans, sialic acid and mannose-containing species, are involved beside glycosaminoglycans (GAGs), heparan sulfate and chondroitin sulfate in the binding of full length (1--68) RANTES not only to CCR5 positive human primary lymphocytes or macrophages but also to CCR5 negative monocytic U937 cells.
Mbemba, Elisabeth +4 more
openaire +2 more sources
, 2014 A-C. Cell surface expression of CCR5 on sorted CCR5-/CR1 (A), CCR5-/CR2 (B) and CCR5-/CR3 (C) TZM.bl cells as compared to mock-transduced TZM.bl cells. D-F.
Chaobaihui Ye (679490) +5 more
core +1 more source
Surface CCR5 conformation localization within U87.CD4.CCR5-GFP cells.
, 2014 Representative images from (A-D) U87.CD4.CCR5-GFP or (E-H) 293-Affinofile cells stained with the indicated CCR5 MAbs (red). CCR5 MAb 45531 exhibited a more punctate staining pattern than other MAbs.
Thomas J. Hope (108657) +2 more
core +1 more source
Bioinformatically analyzed relationships between specific human genes associated with HIV attachment
Инфекция и иммунитетIntroduction. Assessing interaction between the human immunodeficiency virus (HIV) and human factors is crucial for understanding the disease pathogenesis. HIV triggers an immune response that involves numerous cellular and molecular processes related to
Vladimir S. Davydenko +5 more
doaj +1 more source
CCR5 is a suppressor for cortical plasticity and hippocampal learning and memory
eLife, 2016 Although the role of CCR5 in immunity and in HIV infection has been studied widely, its role in neuronal plasticity, learning and memory is not understood.
Miou Zhou +12 more
doaj +1 more source
Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy
Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley +1 more source
CCR5 gene disruption by RNA-guided Cas9 endonuclease in transduced CEM ss-CCR5 cells.
, 2014 A. Cell surface expression of CCR5 on CEMss-CCR5 cells co-transduced with lentiviral vectors expressing Cas9-HA-NLS and one of sgRNA (CR2 or GF1) as compared to mock-transduced CEMss-CCR5 cells. B.
Chaobaihui Ye (679490) +5 more
core +1 more source
CCR5 structural plasticity shapes HIV-1 phenotypic properties.
PLoS Pathogens, 2018 CCR5 plays immune functions and is the coreceptor for R5 HIV-1 strains. It exists in diverse conformations and oligomerization states. We interrogated the significance of the CCR5 structural diversity on HIV-1 infection.
Philippe Colin +17 more
doaj +1 more source